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201-220 of 310 results by Robert Flint

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Title: Modified Brian Injury Guidelines and Transfers

Category: Trauma

Keywords: BIG, transfer, head trauma, brain injury (PubMed Search)

Posted: 6/9/2024 by Robert Flint, MD (Updated: 7/21/2026)

This study used the modified Brain injury Guidelines retrospectively to assess whether the guidelines would have saved transfers to their level one facility safely.  They concluded the guidelines would have effectively prevented unnecessary  mBIG 1 and mBIG2 transfers with no patient harm.

TABLE 1 - Modified Brain Injury Guidelines Radiologic Stratification, as per Kahn et al.

  mBIG 1 mBIG 2 mBIG 3
Skull fracture No Non-displaced Displaced
SDH ?4 mm 4–7.9 mm ?8 mm
EDH No No Yes
SAH ?3 sulci and <1 mm Single hemisphere or 1–3 mm Bihemisphere or >3 mm
IVH No No Yes
IPH ?4 mm 4–7.9 mm ?8 mm or multiple

EDH, epidural hematoma; IPH, intraparenchymal hemorrhage; IVH, intraventricular hemorrhage; SAH, subarachnoid hemorrhage.

Show References

Shen, Aricia MD; Mizraki, Nathaniel MD; Maya, Marcel MD; Torbati, Sam MD; Lahiri, Shouri MD; Chu, Ray MD; Margulies, Daniel R. MD; Barmparas, Galinos MD. Reducing low-value interhospital transfers for mild traumatic brain injury. Journal of Trauma and Acute Care Surgery 96(6):p 944-948, June 2024. | DOI: 10.1097/TA.0000000000004291



Title: Oral anticoagulants and head injury

Category: Trauma

Posted: 6/1/2024 by Robert Flint, MD (Updated: 6/1/2024)

In this Scandinavian study looking at 2,362 head injury patients on oral anticoagulants, the authors found only 5 cases of delayed hemorrhage and none of the five  underwent neurosurgery.  The authors concluded:

“In patients with head trauma, on oral anticoagulation, the incidence of clinically relevant delayed intracranial hemorrhage was found to be less than one in a thousand, with detection occurring four days or later after initial presentation.”

It would appear based on this study and others that it is safe to discharge these patients with a normal head CT and giving strict return precautions for headache, nausea, vomiting or other changes.

Show References

André, L., Björkelund, A., Ekelund, U. et al. The prevalence of clinically relevant delayed intracranial hemorrhage in head trauma patients treated with oral anticoagulants is very low: a retrospective cohort register study. Scand J Trauma Resusc Emerg Med 32, 42 (2024). https://doi.org/10.1186/s13049-024-01214-0



Title: Importance of Frailty Screening in ED patients

Category: Geriatrics

Keywords: Geriatrics, frailty, screening (PubMed Search)

Posted: 5/27/2024 by Robert Flint, MD

This Delphi study and companion editorial highlight current thought on frailty screen in emergency department patients. Key takeaways are:

  1. Those with a high degree of frailty may have different care goals and needs than those with lower frailty. 
    2. Screening should include functional status in the past 2-4 weeks. 
    3. Screening should include functional ability, cognition, mobility, medication use and social situation. 
    4. Screening is practical and can be completed quickly. 
    5. Screening should occur in the first 4 hours of an ED visit. 
    6. ED protocols designed for streamlined, single problem focused visits won’t work well for those with a high degree of frailty.

Emergency departments should be instituting procedures that incorporate screening older patients for frailty. These references are a good starting point.

Show References

  1. Elizabeth Moloney, Mark R O’Donovan, Christopher R Carpenter, Fabio Salvi, Elsa Dent, Simon Mooijaart, Emiel O Hoogendijk, Jean Woo, John Morley, Ruth E Hubbard, Matteo Cesari, Emer Ahern, Roman Romero-Ortuno, Rosa Mcnamara, Anne O’Keefe, Ann Healy, Pieter Heeren, Darren Mcloughlin, Conor Deasy, Louise Martin, Audrey Anne Brousseau, Duygu Sezgin, Paul Bernard, Kara Mcloughlin, Jiraporn Sri-On, Don Melady, Lucinda Edge, Ide O’Shaughnessy, Jill Van Damme, Magnolia Cardona, Jennifer Kirby, Lauren Southerland, Andrew Costa, Douglas Sinclair, Cathy Maxwell, Marie Doyle, Ebony Lewis, Grace Corcoran, Debra Eagles, Frances Dockery, Simon Conroy, Suzanne Timmons, Rónán O’Caoimh, Core requirements of frailty screening in the emergency department: an international Delphi consensus study, Age and Ageing, Volume 53, Issue 2, February 2024, afae013, https://doi.org/10.1093/ageing/afae013
  2. James David van Oppen, Mason Suzanne, Frailty screening in the Emergency Department: why does it matter?, Age and Ageing, Volume 53, Issue 4, April 2024, afae056, https://doi.org/10.1093/ageing/afae056


Title: Lefort Fracture Review

Category: Trauma

Keywords: Lefort, facial, trauma, fracture (PubMed Search)

Posted: 5/26/2024 by Robert Flint, MD (Updated: 7/21/2026)

On exam, assess for facial instability and airway patency. CT scan is the imaging of choice. The higher the number, the more complex the fracture, the more unstable and the more difficult the airway managment will be. Look for open lacerations or blood in the sinuses and treat with antibiotics if these are found. Consult ENT or plastics urgently for further management. 
The reference is a nice review of these fractures    

Show References

https://medicine.uiowa.edu/iowaprotocols/facial-fracture-management-handbook-lefort-fractures



Title: Medications that cause orthostatic hypotension

Category: Cardiology

Posted: 5/24/2024 by Robert Flint, MD (Updated: 7/21/2026)

Show References

X British Geriatric Society 5/24/24



Title: Does IV contrast help identify injuries in blunt abdominal trauma patients?

Category: Ultrasound

Keywords: Abdomen, ultrasound, trauma, contrast (PubMed Search)

Posted: 5/23/2024 by Robert Flint, MD (Updated: 7/21/2026)

This very small study looked at the utility of using IV contrast media to enhance abdominal sonography in identifying injuries in blunt abdominal trauma patients. The comparison was CT scanning of the abdomen to identify injuries. The study concluded:

“With the addition of contrast and careful inspection of solid organs, abdominal sonography with contrast performed by the emergency physician improves the ability to rule out traumatic findings on abdominal CT. CEUS performed by emergency physicians may miss injuries, especially in the absence of free fluid, in cases of low-grade injuries, simultaneous injuries, or poor-quality examinations.”

To me, this is a limited study and the technique is not ready for wide spread use but further study is warranted.

Show References

Contrast-enhanced point of care ultrasound for the evaluation of stable blunt abdominal trauma by the emergency physician: A prospective diagnostic study

Viviane Donner MD, Julian Thaler MD, Wolf E Hautz Prof. Dr.Med, MME, Thomas Christian Sauter Prof. Dr.Med, MME, Daniel Ott MD, Karsten Klingberg MD, Aristomenis K Exadaktylos Prof.Dr.Med, Beat Lehmann MD

First published: 19 April 2024

Journal of the American College of Emergency Physicians OpenVolume 5, Issue 2

https://doi.org/10.1002/emp2.13123



Title: Vasopressors in hemorrhagic shock

Category: Trauma

Keywords: vasopressor, hemorrhage, shock, trauma (PubMed Search)

Posted: 5/19/2024 by Robert Flint, MD (Updated: 7/21/2026)

In this podcast, the concept of vasopressor use in hemorrhagic shock is discussed.  Key take away points:

  1. US and UK literature is much less supportive of vasopressor use in hemorrhagic shock than continental European literature.
  2. Concept is while filling the tank with blood, getting some squeeze in the venous system to keep it circulating.
  3. If a young trauma patient has cool extremities, they are already vasogenic and unlikely to benefit from vasopressors. Warm extremities mean they may benefit from vasopressors.
  4. Norepinephrine is the drug of  choice. Aim for a maintenance dose of 3-5 mcg/min and no need to titrate because you are not looking for arterial constriction, just venous tone.
  5. Low dose Vasopressin drip may be beneficial as well, however more literature is needed. 
  6. Blood is still the answer in these patients! Vasopressors are an adjunct to creating a balanced resuscitation.

Show References

https://emcrit.org/emcrit/vasopressors-for-hemorrhage/



Title: IV antibiotics prior to discharge in UTI: any benefit?

Category: Administration

Posted: 5/13/2024 by Robert Flint, MD (Updated: 7/21/2026)

This retrospective study looked at patients diagnosed with urinary tract infections receiving an IV dose of antibiotics  prior to discharge and compared ED length of stay and return visit rate. They found:

“Parenteral antibiotic administration in the ED was associated with a 60-minute increase in ED LOS compared with those who received an oral antibiotic (P < 0.001) and a 30-minute increase in ED LOS compared with no antibiotic (P < 0.001). No differences were observed in revisits to the ED at 72 hours”

Appears no benefit to the practice of IV antibiotics prior to discharge in UTI patients.

Show References

Association between antibiotic administration before discharge and emergency department length of stay for urinary tract infection: A retrospective analysis

Mohammed A. Alrashed Stephen J. Perona Mark C. Borgstrom Elias Ramirez-Moreno

JAPhA VOLUME 64, ISSUE 3, 102020, MAY 2024

Published:January 29, 2024DOI:https://doi.org/10.1016/j.japh.2024.01.016



Title: Brain Injury Associated Shock

Category: Trauma

Posted: 5/12/2024 by Robert Flint, MD (Updated: 7/21/2026)

Hemodynamic instability in trauma patients is most often associated with hemorrhagic shock, however, there is an entity known as brain injury associated shock (BIAS). BIAS is thought to be associated with catecholamine surges secondary to brain injury.  BIAS is found in both isolated head injury pts as well as multi-trauma patients. Studies have identified BIAS in 13% of adult  trauma patients and up to 40% of pediatric major trauma patients.  
We know hypotension in brain injury worsens outcome.  We should assume hemorrhagic etiology until we prove otherwise. Once we suspect BIAS and have excluded hemorrhagic etiology our strategy should switch to  blood pressure support using non-blood product management.

Show References

Partyka C, Alexiou A, Williams J, Bliss J, Miller M, Ferguson I. Brain Injury Associated Shock: An Under-Recognized and Challenging Prehospital Phenomenon. Prehospital and Disaster Medicine. Published online 2024:1-6. doi:10.1017/S1049023X24000359



Title: Blunt Cardiac Injury

Category: Trauma

Keywords: trauma, blunt, cardiac injury, shock, thoracic (PubMed Search)

Posted: 5/5/2024 by Robert Flint, MD

Blunt Cardiac Injury is a continuum from asymptomatic, not clinically relevant to catastrophic, life ending disease . Consider blunt cardiac injury in patients with significant force to the chest wall or sudden deceleration injuries (motor vehicle crashes, motorcycle crashes, falls from height etc.). This algorithm is helpful when working up patients suspected of having significant blunt cardiac injury. 

Show References

Biffl, Walter L. MD; Fawley, Jason A. MD; Mohan, Rajeev C. MD. Diagnosis and management of blunt cardiac injury: What you need to know. Journal of Trauma and Acute Care Surgery 96(5):p 685-693, May 2024. | DOI: 10.1097/TA.0000000000004216



Title: Prescribing antihypertensives decreased 30 day adverse events and re-visits

Category: Cardiology

Posted: 4/28/2024 by Robert Flint, MD

In a cohort of  93,512 ED patients discharged with a diagnosis of hypertension there were 4400 who received a prescription for antihypertensives. The group receiving a prescription had fewer 30 day revisits and adverse events such as MI, CHF, etc. 

Previous study’s have found it is safe to prescribe antihypertensives from the ED. 

 This study is limited by the fact it is not a randomized control trial and there are many variables as to why the select patients received prescriptions  

The authors conclude: “Prescription antihypertensive therapy for discharged ED patients is associated with a 30-day decrease in severe adverse events and ED revisit rate.”

Show References

Antihypertensive prescription is associated with improved 30-day outcomes for discharged hypertensive emergency department patients

Brett R. Todd MD, Yuying Xing PhD, Lili Zhao PhD, An Nguyen MD, Robert Swor DO, Lauren Eberhardt, Amit Bahl MD

Journal of the American College of Emergency Physicians OpenVolume 5, Issue 2 e13138

https://doi.org/10.1002/emp2.13138



Title: Goals of care aren’t being discussed prior to trauma transfers

Category: Trauma

Posted: 4/24/2024 by Robert Flint, MD (Updated: 7/21/2026)

A small study retrospectively looking at recorded calls to a level 1 trauma center transfer line specifically looking at patients who died or were discharged to hospice without surgical intervention found only 10% had goals of care discussed prior to transfer. Most were brain hemorrhage patients. 
As a transferring facility, clearly outlining goals of care and addressing futility of care can have a major impact on trauma transfers and the cost and family burden associated with transfers.

Show References

Goals of care are rarely discussed prior to potentially futile trauma transfer: Is it okay to say “No”?

Trenga-Schein, Nellie BA; Zonies, David MD, MPH, MBA, FACS, FCCM, FACHE; Cook, Mackenzie MD, FACS

Journal of Trauma and Acute Care Surgery 96(4):p 583-588, April 2024. | DOI: 10.1097/TA.0000000000004215



Title: Pediatric Important Abdominal Injury Decision Tool

Category: Trauma

Posted: 4/21/2024 by Robert Flint, MD

PECARN  has a decision tool to identify blunt trauma patients under age 18 who are low probability for important intra-abdominal injuries. The questions to ask are:

  1.  Evidence of abdominal wall trauma/seatbelt sign
  2. GCS <14 with abdominal trauma
  3. Abdominal tenderness
  4. >1 of thoracic wall trauma, vomiting, complaint of abdominal pain, decreased breath sounds

Answering no to all yields  <0.1% chance of intra-abdominal trauma requiring intervention.  (See MedCalc link for other calculations)

A prospective validation study in the Lancet yielded 100% sensitivity and negative predictive value in 7542 patients under age 18  

This tool can likely be used to guide imaging choices in pediatric blunt abdominal trauma patients

Show References

  1. Holmes JF, Yen K, Ugalde IT, Ishimine P, Chaudhari PP, Atigapramoj N, Badawy M, McCarten-Gibbs KA, Nielsen D, Sage AC, Tatro G, Upperman JS, Adelson PD, Tancredi DJ, Kuppermann N. PECARN prediction rules for CT imaging of children presenting to the emergency department with blunt abdominal or minor head trauma: a multicentre prospective validation study. Lancet Child Adolesc Health. 2024 May;8(5):339-347. doi: 10.1016/S2352-4642(24)00029-4. PMID: 38609287.
  2. https://www.mdcalc.com/calc/3971/pecarn-pediatric-intra-abdominal-injury-iai-algorithm


Title: Implementation of airway guidelines improved TBI survival

Category: Trauma

Posted: 4/14/2024 by Robert Flint, MD (Updated: 7/21/2026)

This study looked at survival pre and post implementation of an airway guideline for prehospital traumatic brain injury (TBI) patients who received positive pressure airway interventions.  The guideline “focused on the avoidance and aggressive treatment of hypotension and 3 airway-related goals: (1) prevention or treatment of hypoxia through early, high-flow oxygen administration; (2) airway interventions to optimize oxygenation or ventilation when high-flow oxygen was insufficient; and (3) prevention of hyperventilation or hypocapnia by using ventilation adjuncts (ie, rate timers, flow-controlled ventilation bags, end-tidal carbon dioxide monitoring).”

Post implementation, survival to admission increased in all severity levels of TBI and in the most severely injured, survival to discharge improved. 

Useful for those involved in prehospital education and as a reminder for in hospital airway management  in TBI patients.

Show References

Gaither JB, Spaite DW, Bobrow BJ, et al. EMS Treatment Guidelines in Major Traumatic Brain Injury With Positive Pressure Ventilation. JAMA Surg. 2024;159(4):363–372. doi:10.1001/jamasurg.2023.7155



Title: Is a systolic blood pressure of 90 the best measure of illness in trauma patients?

Category: Trauma

Keywords: Trauma, blood pressure, shock index, predictor, mortality (PubMed Search)

Posted: 4/8/2024 by Robert Flint, MD

Traditionally, a systolic blood  pressure (SBP) of 90 has been used as a marker of severe illness in trauma patients. This study looked at a large database and found shock index (SI) and systolic blood pressure were the best predictors of early mortality in trauma patients. 
They found: 

prehospital SI 0.9 and SBP 110,

ED SI 0.9 and SBP 112,

and

in elderly 

prehospital SI 0.8 SBP 116 

ED SI 0.8 SBP 121 

were the cutoffs to predict early mortality.  
We should rethink our protocols and approach to trauma patients using a higher systolic blood pressure than 90. Also note elderly had a different number than younger trauma patients.

Show References

April MD, Fisher AD, Rizzo JA, Wright FL, Winkle JM, Schauer SG. Early Vital Sign Thresholds Associated with 24-Hour Mortality among Trauma Patients: A Trauma Quality Improvement Program (TQIP) Study. Prehosp Disaster Med. 2024 Apr 2:1-5. doi: 10.1017/S1049023X24000207. Epub ahead of print. PMID: 38563282.



Title: No evidence to support use of markers for penetrating trauma radiographs

Category: Trauma

Keywords: Marker, penetrating trauma, radiopaque (PubMed Search)

Posted: 4/7/2024 by Robert Flint, MD (Updated: 7/21/2026)

Using radiopaque markers such as paperclips to mark penetrating wounds prior to radiographs has been taught in trauma bays for decades. This article points out there is no evidence to support this practice and is purely based on expert opinion. With the heavy use of CT imaging to assess wound tracks, the use of markers on plain films appears to be of limited utility.

Show References

Sarfaraz K, Nemeth J, Bahreini M. The use of radiopaque markers is medical dogma. Acad Emerg Med. 2024 Feb;31(2):193-194. doi: 10.1111/acem.14858. Epub 2024 Feb 6. PMID: 38112251.



Title: Emergency Department visit for alcohol related events is a predictor of future adolescent and young adult mortality

Category: Toxicology

Keywords: Alcohol, mortality, predictor, trauma (PubMed Search)

Posted: 3/31/2024 by Robert Flint, MD (Updated: 7/21/2026)

This retrospective population cohort study looked at  first time ED visits for adolescents and young adults comparing those with visits related to alcohol to those not related to alcohol. Patients in the alcohol related visit group had  a threefold increased one year mortality rate.  Cause of death was trauma, poisoning by drug and alcohol. Risk factors include being male, age 20-29, history of mental health and having a visit for withdrawal.  

Adolescents and young adults presenting to an emergency department for an alcohol related complaint are high risk for one year mortality and deserve intervention and appropriate referral.

Show References

Academic Emergency MedicineVolume 31, Issue 3 p. 220-229
Mortality in adolescents and young adults following a first presentation to the emergency department for alcohol

Lyndsay D. Harrison MSc, Asnake Y. Dumicho MSc, Anan Bader Eddeen MSc, Peter Tanuseputro MD, MHSc, Claire E. Kendall MD, PhD, Jess G. Fiedorowicz MD, PhD, Tea Rosic MD … See all authors

https://doi.org/10.1111/acem.14843



Title: A benzodiazepine sparing protocol for alcohol withdrawal in trauma patients

Category: Trauma

Keywords: Alcohol, withdrawal, trauma, protocol, sparing (PubMed Search)

Posted: 3/24/2024 by Robert Flint, MD (Updated: 7/21/2026)

This study compared  admitted trauma patients with alcohol withdrawal or those at risk of withdrawal before and after a  benzodiazepine sparing protocol (using clonidine and gabapentin) was initiated. They found a lower daily CIWA score and significantly less lorazepam use in the benzodiazepines sparing group. This sparing protocol appears to be safe and effective.

Show References

Eliminating the benzos: A benzodiazepine-sparing approach to preventing and treating alcohol withdrawal syndrome

McCullough, Mary Alyce MD; Miller, Preston R. III MD; Martin, Tamriage MD; Rebo, Kristin A. PharmD; Stettler, Gregory R. MD; Martin, Robert Shayn MD; Cantley, Morgan PharmD; Shilling, Elizabeth H. PhD; Hoth, James J. MD, PhD; Nunn, Andrew M. MD

Journal of Trauma and Acute Care Surgery 96(3):p 394-399, March 2024. | DOI: 10.1097/TA.0000000000004188



Title: Use of hospice for discharge in geriatric trauma patients

Category: Trauma

Keywords: Geriatric trauma, outcome, hospice (PubMed Search)

Posted: 3/17/2024 by Robert Flint, MD (Updated: 7/21/2026)

This was a database study of nearly 2 million trauma patients over age 65 who were discharged looking at all levels of trauma centers. The authors found:

“Dominance analysis showed that proportion of patients with Injury Severity Score of >15 contributed most to explaining hospice utilization rates (3.2%) followed by trauma center level (2.3%), proportion White(1.9%), proportion female (1.5%), and urban/rural setting (1.4%).”

 Level one centers had the lowest level of discharge to hospice. The authors felt: “As the population ages, accurate assessment of geriatric trauma outcomes becomes more critical. Further studies are needed to evaluate the optimal utilization of hospice in end-of-life decision making for geriatric trauma.”

Show References

Variation in hospice use among trauma centers may impact analysis of geriatric trauma outcomes: An analysis of 1,961,228 Centers for Medicare and Medicaid Services hospitalizations from 2,317 facilities

Fakhry, Samir M. MD, FACS; Shen, Yan PhD; Wyse, Ransom J. MPH; Garland, Jeneva M. PharmD; Watts, Dorraine D. PhD

Journal of Trauma and Acute Care Surgery 94(4):p 554-561, April 2023. | DOI: 10.1097/TA.0000000000003883



Title: Older patient head trauma, NEXUS data

Category: Trauma

Posted: 3/10/2024 by Robert Flint, MD (Updated: 7/21/2026)

This secondary analysis of the NEXUS head injury data found patients over 65:

-sustained more significant injuries than younger pts

-presented more frequently with occult injuries

-when they required neurosurgery intervention only 16% went home, 32% were discharged to rehab facility and 41%  died

-mechanism of injury was most commonly fall from standing

-mortality rates were highest for fall from ladder and auto vs. pedestrian injuries

The authors concluded: “Older blunt head injury patients are at high risk of sustaining serious intracranial injuries even with low-risk mechanisms of injury, such as ground-level falls. Clinical evaluation is unreliable and frequently fails to identify patients with significant injuries. Outcomes, particularly after intervention, can be poor, with high rates of long-term disability and mortality.”

Show References

William R. Mower, Thomas E. Akie, Naseem Morizadeh, Malkeet Gupta, Gregory W. Hendey, Jake L. Wilson, Lorenzo Pierre Leonid Duvergne, Phillip Ma, Pravin Krishna, Robert M. Rodriguez,
Blunt Head Injury in the Elderly: Analysis of the NEXUS II Injury Cohort,
Annals of Emergency Medicine,
2024,



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