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The following is a differential diagnosis for unilateral headaches with typical associated features:
- Migraine headache -> throbbing pain preceded by aura; nausea; photophobia; chronicity.
- Cluster headache -> piercing eye pain; ipsilateral lacrimation and rhinorrhea; group of headaches come periodically in waves.
- Temporal arteritis -> dull ache over temporal artery; associated with arthralgia, myalgia, and anemia; typically in older populations.
- Glaucoma -> eye pain with cloudy appearing cornea; eyeball feels hard; pupillary dilitation may worsen pain.
- Sinusitis -> associated with sinus congestion; tenderness over sinus with or without swelling; typically only relieved with decongestants and/or antibiotics.
- Subarachnoid hemorrhage -> pain may be diffuse or unilateral; sudden onset of severe pain; may be associated with a stiff neck.