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- Guillain-Barre’ Syndrome (GBS) is a group of immune mediated processes characterized by motor, sensory, and autonomic dysfunction of peripheral nerves.
- Classically, GBS is an acute inflammatory demyelinating polyneuropathy (AIDP) consisting of progressive, symmetric, ascending muscle weakness and paralysis, associated with diminished deep tendon reflexes.
- This rare condition, affecting 3,000 to 6,000 Americans annually (1 to 2 out of 100,00 per year), can lead to respiratory failure in severe cases, requiring vigilance in pro-actively administering mechanical ventilation as needed.