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Title: Infections That Cause Temperature-Pulse Dissociation

Category: Infectious Disease

Keywords: Infections, Temperature (PubMed Search)

Posted: 12/29/2008 by Rob Rogers, MD (Updated: 7/21/2026)

This pearl is dedicated to Dr. Michael Rolnick....

 

Infections That Cause Temperature-PulseDissociation

Certain infections may cause temperature-pulse dissociation (relative bradycardia in association with fever).

Remember that normally there will be an increase in pulse rate by 10 bpm for every 1 degree increase in temperature. So, if a patient has a temperature of 103 F, expect them to be tachycardic.

Any intracellular organism has the potential to cause a relative bradycardia (Faget's sign)

Infections that cause dissociation:

  • Salmonella typhi
  • C burnetii (agent of Q fever)
  • Chlamydia infections
  • Dengue fever

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