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Title: Sarcopenia as a marker of frailty in trauma patients?

Category: Trauma

Keywords: Sarcopenia, trauma, ct scan (PubMed Search)

Posted: 3/9/2025 by Robert Flint, MD (Updated: 7/21/2026)

Having a readily measurable variable to identify frailty on admission for critically injured patients would help prognosticate morbidity, mortality, and discharge destination. Sarcopenia has been used to prognosticate length of stay, discharge destination, and physical function recovery in oncology and general surgery patients. Sarcopenia is defined as “age-related progressive loss of muscle mass and strength. The main symptom of the condition is muscle weakness. Sarcopenia is a type of muscle atrophy primarily caused by the natural aging process. Scientists believe being physically inactive and eating an unhealthy diet can contribute to the disease.” 1. This study looked at admission CT scan psoas muscle sarcopenia in 197 critically injured patients. The authors concluded:

“For trauma critical care patients, sarcopenia on admission CT was associated with dependent discharge destination and therefore is unfavourable. Defining sarcopenia early in a trauma patient’s critical care admission may help to identify those at risk of poor outcomes.” 2

References

1. Sarcopenia (Muscle Loss): Symptoms & Causes

2. Badminton R, Christie R, Brohi K, Cole E. Pre-injury sarcopenia and the association with discharge destination in critical care trauma patients. Trauma. 2025;27(1):57-64. doi:10.1177/14604086231214878


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