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A study looking at 177 trauma patients (predominately skiing injuries) treated with oral trans mucosal fentanyl (600 and 800 mcg dosing) found a statistically and clinically significant reduction in pain. This therapy could be an adjunct to patients who require pain relief but IV access is delayed for various reasons.
References
Pietsch, U., Fischer, H., Rüst, C.A. et al. Oral transmucosal fentanyl citrate analgesia in prehospital trauma care: an observational cohort study. Scand J Trauma Resusc Emerg Med 31, 2 (2023). https://doi.org/10.1186/s13049-023-01066-0