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Fluids in Acute Liver Failure
- Acute liver failure is often complicated by intravascular volume depletion - insensible losses, vomiting, poor oral intake
- Early and adequate fluid resuscitation is mandatory
- AVOID lactated Ringer's solution - exogenous lactate load is poorly tolerated by lack of hepatic function
- AVOID dextrose containing water solutions - will lead to hyponatremia and increase the risk of cerebral edema
References
Auzinger G, Wendon J. Intensive care management of acute liver failure. Curr Opin Crit Care 2008;14:179-88.