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Title: Risk of Bleed with IV tPA

Category: Neurology

Keywords: tPA, stroke, intracerebral hemorrhage (PubMed Search)

Posted: 3/19/2008 by Aisha Liferidge, MD (Updated: 9/4/2026)

The risk of symptomatic intracerebral hemorrhage after use of IV tPA for acute stroke is 6% (within 36 hours of administration).

The NINDS tPA Stroke Study Group. "Intracerebral Hemorrhage after Administration of Intravenous tPA for Ischemic Stroke." Stroke. 1997; 28: 2109-18.