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Title: Sepsis Mimics

Category: Critical Care

Posted: 2/14/2017 by Mike Winters, MBA, MD (Updated: 7/21/2026)

Sepsis Mimics

  • Emergency physicians are well versed in the resuscitation of patients with sepsis and septic shock.
  • With the recent publication of the 2016 SSC Guidelines and the emphasis in meeting various quality measures, sepsis is routinely included in the differential diagnosis of critically ill patients.
  • Notwithstanding, it is important to consider other disease states that can present similarly to sepsis or septic shock.  Some of these include:
    • Anaphylaxis
    • Adrenal insufficiency
    • DKA
    • Thyroid storm
    • Toxic ingestion or withdrawal

References

Long B, Koyfman A. Clinical mimics: An emergency medicine-focused review of sepsis mimics. J Emerg Med. 2017; 52:34-42.


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