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Injury is often caused by sudden dorsiflexion on a plantar flexed foot w/ the knee in extension or similarly sudden knee extension with the ankle in a dorsiflexed position.
Injury has a predilection for the poorly conditioned middle-aged athlete, with "thick calves" who are engaged in strenuous activity
Strains are treated with ice, analgesics, and compression (decreases hematoma size and facilitates healing)
Also, consider casting/splinting as dictated by injury severity, such as with a night splint or a CAM boot.
Severe strains and ruptures can be splinted in plantar flexion for 3 weeks.
References
Gallo et al. Common Leg injuries of long-distance runners:Anatomic and Biomechanical approach. Sports Health. 2012