University of Maryland School of Medicine logo
Emergency Medicine
All Departments
UMSOM Assistant
UMEM Educational Pearls
  • Home
  • Departments
  • Emergency Medicine
  • CME
  • UMEM Educational Pearls
  • CME
  • Courses and Conferences
  • Free Open Access Medical Education
  • UMEM Educational Pearls

Search

Title: Ice-Cold Crystalloids for Therapeutic Hypothermia

Category: Critical Care

Posted: 2/21/2012 by Mike Winters, MBA, MD (Updated: 7/21/2026)

Ice-Cold Crystalloid for Therapeutic Hypothermia

  • Therapeutic hypothermia (TH) is a critical component in the care of patients with ROSC from out-of-hospital cardiac arrest.
  • Despite recent guidelines, initiation of TH in the ED for appropriate patients remains less than optimal.
  • Reported barriers to the induction of TH in the ED include lack of familiarity, lack of collaboration with the ICU, access to special equipment, and the logistics of cooling.
  • A recent analysis of studies on the use of ice-cold crystalloids (ICC) found that an infusion of 40 C fluid is a safe, effective, inexpensive, and readily available method for inducing TH.
  • Importantly, no study reported any significant hemodynamic complication (i.e. CHF) from the use of ICC.
  • Lastly, once the target temperature has been reached, ICC alone cannot maintain TH.  Additional methods, such as surface cooling blankets or ice packs, should be used.

References

Arulkumaran N, Ball SJ. Use of ice-cold crystalloid for inducing mild therapeutic hypothermia following out-of-hospital cardiac arrest. Resuscitation 2012;83:151-8.


University of Maryland School of Medicine logo
  • Departments
  • Programs
  • Research Centers
  • Institutes
  • Graduate Education
  • CIBR Cores
  • Offices of the Dean
    • University of Maryland, Baltimore
    • University of Maryland Medical Center
    • Medical Alumni Association of the University of Maryland
    • Health Sciences and Human Services Library
University of Maryland School of Medicine
655 W. Baltimore Street
Baltimore, MD 21201
Contact Us

© University of Maryland School of Medicine

    • Webmaster
    • Web Accessibility
    • Site Index
    • UMB Hotline
    • Employment
    • Map