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Potential Causes of Neonatal Apnea and Bradycardia
• Central nervous system
Intraventricular hemorrhage, drugs maternal/fetal, seizures, hypoxic injury, herniation, neuromuscular disorders, brainstem infarction or anomalies (e.g., olivopontocerebellar atrophy), general anesthesia.
• Respiratory
Pneumonia, obstructive airway lesions, upper airway collapse, atelectasis, extreme prematurity (<1,000 g), phrenic nerve paralysis, severe hyaline membrane disease, pneumothorax, hypoxia, malformations of the chest.
• Infectious
Sepsis, meningitis (bacterial, fungal, viral), RSV
• Metabolic
Hypoglycemia, hyper/hyponatrmia, hyperammonemia, decreased organic acids, hypothermia.
• Cardiovascular
Hypotension/hypovolemia, heart failure, PDA, anemia, vagal tone.