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Title: What's the diagnosis? Pearl submitted and written by Dr. Zachary Dezman

Category: Visual Diagnosis

Posted: 10/31/2011 by Haney Mallemat, MD (Updated: 10/31/2011)

Question

72 year-old man, one-week post right fem-pop bypass presents with painful blue and black toe. Diagnosis?


Answer

Answer: Blue-Toe Syndrome

  • Blue-toe syndrome is acute digital-ischemia, presenting as one or more cold, painful, and cyanotic toes (or other digits).
  • Multiple causes:
    • Emboli (most common)
    • Cholesterol emboli from recent endovascular procedure or atherosclerotic plaque rupture
    • Vascular aneurysm
    • Infectious (e.g., endocarditis)
    • Medications (e.g., warfarin)
    • Drugs (e.g., cocaine, methamphetamine, etc.)
  • Emergency Department evaluation should focus on determining the underlying cause to prevent limb loss.
  • Patients should have emergent vascular consult and admission for potential revascularization.

References

Hirschman, J. et al. Blue (or purple) toe syndrome. J Am Acad Dermatol.2009 Jan;60(1):1-20

O'Keeffe S, et al. Blue toe syndrome: Causes and management.Arch Intern Med. 1992 Nov;152(11):2197-202.

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