Cardiothoracic Anesthesiology

• Patrick Odonkor, MB,ChB, Associate Professor and Division Chief 
• Seema Deshpande, MBBS, Associate Professor and Fellowship Director
• Susan Sankova, MD, Assistant Professor and Associate Fellowship Director
• Richard T. Booth, MD, Assistant Professor
• Ross O. Carpenter,  MD, Assistant Professor
• Ashanpreet Grewal, MD, Assistant Professor
• Reney Henderson, MD, Assistant Professor
• Kimberly N. Hollander, MD, Assistant Professor
• Samhati Mondal, MBBS, Associate Professor
• Erik R. Strauss, MD, Associate Professor
• Brittney Williams, MD, Associate Professor

• Inna Shats, MA, BS, RDCS, FASE, Chief Sonographer - EMAIL
• Bobby Ezzati, RCS - EMAIL
• Kristen Jordan, RDCS - EMAIL
• Sarah Krejak, RDCS - EMAIL
• Glenda March - EMAIL

Education: Our faculty members actively in teach residents, fellows, and medical students in and out of ORs. Anesthesiology residents are exposed to a wide variety of anesthetic techniques along with TEE, and blood conservation techniques.  Participation in Cardiothoracic Fellowship provides further specialization in cardiothoracic anesthesiology by providing extensive TEE training, patient blood management, and research opportunities. Dr Odonkor currently serves as an ABA Oral Board Examiner, ABA MOCA minute question writer and member of the Standardized Oral Examination Committee at the ABA.

Research: Cardiothoracic Division members actively conduct their own research, participate in multi-center clinical trials, and support cardiac surgeons in evaluating new surgical techniques and cardiopulmonary devices. One of the major research focuses is coagulation monitoring in complex cardiac surgery. One of the major research focuses in the Division is coagulation monitoring in complex cardiac surgery. Dr. Williams spends a significant proportion of her time in the laboratory and her research interests include cardiopulmonary bypass associated coagulopathy and sepsis induced coagulopathy. Drs. Williams, Strauss and Odonkor are actively involved in the Cardiac Xenotransplantation program at the University of Maryland School of Medicine, which has produced the longest surviving orthotopic pig heart to baboon xenotransplant. Dr. Strauss was involved in the first successful minimally invasive intraoperative TEE guided “HARPOON” assisted repair of the Mitral Valve in North America.

Service:

• Dr. Strauss was selected to serve as a member of the SCA research committee.
• Dr. Henderson was selected to serve as a member of the SCA Blood Conservation Committee. He also serves on the Faculty Senate, Diversity Advisory Committee and Admission Committee at the University of Maryland School of Medicine
• Dr. Odonkor serves as a member on the Perfusion Advisory Committee of the Maryland Board of Physicians.

Oral Presentation:

•  Henderson RA, Hematological Effects After Autologous Blood Infusion in Cardiac Surgical Patients, SABM, University of Maryland, Baltimore, Oral. 2020

Strauss ER, Li S, Henderson R, Carpenter R, Guo D, Thangaraju K, Katneni U, Buehler PW, Gobburu JV, Tanaka KA. A Pharmacokinetic and Plasmin-Generation Pharmacodynamic Assessment of a Tranexamic Acid Regimen Designed for Cardiac Surgery With Cardiopulmonary Bypass. J Cardiothorac Vasc Anesth. 36(8 Pt A), 2473-2482. PMID: 35094925. 2022

Everett L, Davis TA, Deshpande SP, Mondal S. Implementation of Bilateral Rectus Sheath Blocks in Conjunction With Transversus Thoracis Plane and Pectointercostal Fascial Blocks for Immediate Postoperative Analgesia After Cardiac Surgery. Cureus. 14(7), e26592. PMID: 35936156. 2022

Makkad B, Deshpande SP. Con: Interviews for Adult Cardiothoracic Anesthesiology Fellowship Program: In Favor of the In-Person Interview. J Cardiothorac Vasc Anesth. 36(4), 1209-1213. PMID: 34903455. 2022

Bergbower E, Park PS, Deshpande S. The Good, Bad, and Ugly of Inferior Vena Cava (IVC) Filters: Anesthetic Management for IVC Filter Retrieval in the Setting of Filter Thrombosis. Cureus. 2022 Feb 25;14(2):e22591. doi: 10.7759/cureus.22591. PMID: 35371650; PMCID: PMC8958871.

Choi S, Mazzeffi MA, Henderson R, Mondal S, Morita Y, Deshpande S, Tanaka KA. The FIBTEM paradox: Do coronary artery bypass grafting patients with high baseline FIBTEM clot firmness need more allogeneic blood transfusion? Transfusion. 2022 Oct;62(10):2020-2028. doi: 10.1111/trf.17065. Epub 2022 Aug 20. PMID: 36053950.

Fabbro M, Patel PA, Henderson RA, Bolliger D, Tanaka KA, Mazzeffi MA. Coagulation and Transfusion Updates From 2021. J Cardiothorac Vasc Anesth. 36(9), 3447-3458. PMID: 35750604. 2022

Strauss ER, Quinn RW, Pasrija C, Henderson R, Holmes SD, D'Ambra MN, Gammie JS. Intraoperative echocardiographic assessment of mitral valve translocation. Eur J Cardiothorac Surg. 62(2). 62(2):ezac133. PMID: 35277715. 2022

Mazzeffi M, Henderson R, Powell E, Strauss E, Williams B, Tanaka K, Yang S, Deatrick K, Madathil R. Thrombopoietin, Soluble CD40 Ligand, and Platelet Count During Veno-arterial Extracorporeal Membrane Oxygenation. ASAIO J. 68(5), e77-e79. PMID: 34081052. 2022

Mazzeffi M, Henderson R, Krause E, Rabin J, Madathil R, Chow J, Grazioli A, Meyer M, Wu Z, Tanaka K. In Vitro Comparison of Recombinant and Plasma-Derived von Willebrand Factor Concentrate for Treatment of Acquired von Willebrand Syndrome in Adult Extracorporeal Membrane Oxygenation Patients. Anesth Analg. 134(2), 312-321. PMID: 34903705. 2022

Tanaka KA, Henderson R, Thangaraju K, Morita Y, Mazzeffi MA, Strauss E, Katneni U, Buehler PW. In vitro effects of emicizumab on activated clotting time in blood samples from cardiac surgical patients. Haemophilia. 28(1), 183-190. PMID: 34735039. 2022

Denault A, Couture EJ, De Medicis É, Shim JK, Mazzeffi M, Henderson RA, Langevin S, Dhawan R, Michaud M, Guensch DP, Berger D, Erb JM, Gebhard CE, Royse C, Levy D, Lamarche Y, Dagenais F, Deschamps A, Desjardins G, Beaubien-Souligny W. Perioperative Doppler ultrasound assessment of portal vein flow pulsatility in high-risk cardiac surgery patients: a multicentre prospective cohort study. Br J Anaesth. 2022 Nov;129(5):659-669. doi: 10.1016/j.bja.2022.07.053. Epub 2022 Sep 30. PMID: 36184294.

Smeltz AM, Coleman PJ, Mondal S. Pro: Acute Normovolemic Hemodilution Should Be Used in Infective Endocarditis Patients Coming for Primary or Redo Cardiac Surgery. J Cardiothorac Vasc Anesth. 36(8 Pt A), 2811-2814. PMID: 35431117. 2022

Mondal S, Faraday N, Gao W, Singh S, Hebber S, Hollander KN, Metkus TS, Goeddel LA, Bauer M, Bush B, Cho B, Cha S, Ibekwe SO, Mladinov D, Rolleri NS, Lester L, Steppan J, Sheinberg R, Hensley NB, Kapoor A, Dodd-o JM. Selected Transesophageal Echocardiographic Parameters of Left Ventricular Diastolic Function Predict Length of Stay Following Coronary Artery Bypass Graft—A Prospective Observational Study. J Clin Med. 11(14), 3980. PMID: 35887745. 2022

Barrera L, Mondal S. Ethical and Clinical dilemma from an incidental cardiac lipoma in a young and healthy patient. Ann Card Anesth. 25(3)(Jul-Sep 2022), 353-355. PMID: 35799567. 2022

Strauss ER, Odonkor PN, Williams B. Porcine Orthotopic Cardiac Xenotransplantation: The Role and Perspective of Anesthesiologists. J Cardiothorac Vasc Anesth. 36(8), 2847-2850. PMID: 35537973. 2022

Smith Bergbower EA, Odonkor PN. Con: Acute Normovolemic Hemodilution Should not be used in Infective Endocarditis. J Cardiothorac Vasc Anesth. 36(8), 2815-2818. PMID: 35501262. 2022

Odonkor P, Strauss E, Williams B. Ethical considerations during a pioneering surgical procedure: porcine cardiac xenotransplantation. Br J Hosp Med. 83(6), 1-7. PMID: 35787171. 2022

Mohiuddin MM, Goerlich CE, Singh AK, ...,Strauss E, Odonkor P, ..., Griffiths BP. Progressive Genetic Modifications of Porcine Cardiac Xenografts Extend Survival to 9 Months. Xenotransplantation. 29(3), e12744. doi: 10.1111/xen.12744. PMID: 35357044. 2022

Shah A, Goerlich CE, Pasrijah C, Hirsch J, Fisher S, Odonkor P, Strauss E, Ayares D, Mohiuddin M, Griffith BP. Anatomical Differences Between Human and Pig Hearts and Their Relevance for Cardiac Xenotransplantation Surgical Technique. JACC Case Rep. 4(16), 1049-1052. PMID: 36062051. 2022

Pasrija C, Quinn R, Strauss E, Wang L, Tran D, D'Ambra MN, Gammie JS. Translocation of the Mitral Valve in an Acute Large Animal Model. J Cardiovasc Transl Res. DOI: 10.1007/s12265-022-10215-2. PMID: 35175554. 2022

Strauss ER, VanDyck K, Mazzeffi MA. Tranexamic acid for cesarean delivery: induction of a regimen for postpartum hemorrhage?. Am J Obstet Gynecol. PMID: 35998746. 2022

Strauss E, Dahmane E, Judd M, Guo D, Williams B, Meyer M, Gammie JS, Taylor B, Mazzeffi MA, Gobburu JV, Tanaka KA. A Pharmacokinetic and Pharmacodynamic Investigation of an ε-Aminocaproic acid regimen designed for the context of cardiac surgery with cardiopulmonary bypass. J Cardiothorac Vasc Anesth. 35(2), 406-417. PMID: 32811752. 2022

Book Chapter:

Odonkor, P.N., Mondal, S. (2022). Anesthesia Considerations in Global Cardiac Surgery Capacity Development in Emerging Countries. In: Kpodonu, J. (eds) Global Cardiac Surgery Capacity Development in Low an-+d Middle Income Countries. Sustainable Development Goals Series. Springer, Cham. https://doi.org/10.1007/978-3-030-83864-5_22

Lopez K, Suen A, Yang Y, Wang S, Williams B, Zhu J, Hu J, Fiskum G, Cross A, Kozar R, Miller C, Zou L, Chao W. Hypobaria Exposure Worsens Cardiac Function and Endothelial Injury in an Animal Model of Polytrauma: Implications for Aeromedical Evacuation. Shock. Published Ahead of Print. PMID: 33394971. 2021

Chen F, Zou L, Williams B, Chao W. Targeting Toll-Like Receptors in Sepsis - From Bench to Clinical Trials. Antioxid Redox Signal. DOI: 10.1089/ars.2021.0005. PMID: 33588628. 2021

Chow JH, Khanna AK, Kethireddy S, Yamane D, Levine A, Jackson AM, McCurdy MT, Tabatabai A, Kumar G, Park P, Benjenk I, Menaker J, Ahmed N, Glidewell E, Presutto E, Cain S, Haridasa N, Field W, Fowler JG, Trinh D, Johnson KN, Kaur A, Lee A, Sebastian K, Ulrich A, Peña S, Carpenter R, Sudhakar S, Uppal P, Fedeles BT, Sachs A, Dahbour L, Teeter W, Tanaka K, Galvagno SM, Herr DL, Scalea TM, Mazzeffi MA. Aspirin Use Is Associated With Decreased Mechanical Ventilation, Intensive Care Unit Admission, and In-Hospital Mortality in Hospitalized Patients With Coronavirus Disease 2019. Anesth Analg. 132(4), 930-941. PMID: 33093359. 2021

Sankova S, Deshpande S, Miller SP, Tanaka K. Anesthesia in the Postgenomic Era: Commercial Polymorphism Screening in a Cardiac Surgery Patient. Anesth Analg. 132(6):1781-1785. PMID: 33780384. 2021

Deshpande SP, Makkad B. Pro: Length of Adult Cardiothoracic Anesthesiology Fellowship Training Should Be Extended Beyond One Year. J Cardiothor Vasc Anesth. DOI: 10.1053/j.jvca.2021.02.002. PMID: 33653577. 2021

Grewal A, Odonkor P, Ghoreishi M, Deshpande SP. Anesthetic Considerations in Endovascular Repair of the Ascending Aorta. J Cardiothorac Vasc Anesth. S1053-0770(21), S1053-0770. PMID: 34059437. 2021

Mazzeffi M, Judd M, Rabin J, Tabatabai A, Menaker J, Menne A, Chow J, Shah A, Henderson R, Herr D, Tanaka K. Tissue Factor Pathway Inhibitor Levels During Veno-Arterial Extracorporeal Membrane Oxygenation in Adults. ASAIO J. PMID: 33606392. 2021

Pasrija C, Quinn RW, Bernstein D, Tran D, Alkhatib H, Rice M, Morales D, Shah A, Ghoreishi M, Strauss ER, Henderson R, D'Ambra MN, Gammie JS. Mitral Valve Translocation: A Novel Operation for the Treatment of Secondary Mitral Regurgitation. Ann Thorac Surg. 112(6), 1954-1961. PMID: 34419436. 2021

Patel PA, Henderson RA, Bolliger D, Erdoes G, Mazzeffi MA. The Year in Coagulation: Selected Highlights from 2020. J Cardiothorac Vasc Anesth. 35(8), 2260-2272. PMID: 33781668. 2021

Henderson RA, Judd M, Strauss ER, Gammie JS, Mazzeffi MA, Taylor BS, Tanaka KA. Hematologic evaluation of intraoperative autologous blood collection and allogeneic transfusion in cardiac surgery. Transfusion. 61(3), 788-798. PMID: 33423288. 2021

Jain V, Ghosh RK, Bandyopadhyay D, Kondapaneni M, Mondal S, Hajra A, Aronow WS, Lavie CJ. Serum Bilirubin and Coronary Artery Disease: Intricate Relationship, Pathophysiology, and Recent Evidence. Curr Probl Cardiol. 46(3), 100431. PMID: 31350011. 2021

Goerlich CE, Griffith B, Singh AK, Abdullah M, Singireddy S, Kolesnik I, Lewis B, Sentz F, Tatarov I, Hershfeld A, Zhang T, Strauss E, Odonkor P, Williams B, Tabatabai A, Bhutta A, Ayares D, Kaczorowski DJ, Mohiuddin MM. Blood Cardioplegia Induction, Perfusion Storage and Graft Dysfunction in Cardiac Xenotransplantation. Front Immunol. 12, 667093. PMID: 34177906. 2021

Mondal S, Sankova S, Lee K, Sorenson E, Kaczorowski D, Mazzeffi M. Intraoperative and Early Postoperative Management of Patients Undergoing Minimally Invasive Left Ventricular Assist Device Implantation. J Cardiothorac Vasc Anesth. 35(2), 616-630. PMID: 32505605. 2021

Gammie JS, Quinn RW, Strauss ER, Wang L, D'Ambra MN, Hung J, Bernstein DA, Tran D, Rice MK, Holmes SD, Pasrija C. Initial Clinical Experience with Mitral Valve Translocation for Secondary Mitral Regurgitation. Ann Thorac Surg. S0003-4975(21), 00051-5. PMID: 33440174. 2021

Chow JH, Strauss E, Mazzeffi MA. Angiotensin II and Vasoplegia in Cardiac Surgery: Paradigm Changer or Costly Contender?. J Cardiothorac Vasc Anesth. 35(1), 59-60. PMID: 32950345. 2021

Henderson RA. Vascular Anesthesia Procedures. Alan Kaye, eds. Hemostasis, Thrombosis, Transfusion, and Blood Conservation. Oxford University Press: Chapter 3 23p-40p. 2021