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Rocuronium is fast becoming the agent of choice for RSI in the Emergency Department. Here is a head to head comparison of the two drugs to understand why:
| Rocuronium | Succinycholine | |
| Dose | 1-1.2mg/kg | 1mg/kg |
| Onset | 1-1.5min | 1min |
| Duration | 7-12min | 30-40min |
| Histamine Release | No | Minimal Yes |
| CVS Effect | Tachycardia rare | Severe Brady rare |
| Other Adverse Effect | No fasciculations, No ICP effect, No Rhabdo | Fasciculations, increase ICP, rhabdo, movement of displaced Fxs |