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Title: Mycoplasma pneumoniae Induced Rash and Mucositis (MIRM)

Category: Pediatrics

Posted: 3/30/2018 by Rose Chasm, MD (Updated: 7/21/2026)

  • Stevens-Johnsons like rash and mucositis
  • Most common in children and adolescents, with a mean age of 12 years old
  • More common in males than females, 2:1
  • Prodromal symptoms of cough, fever, and malaise precede
  • Mucositis far out of proportion to body rash, 90% vs 10%
  • Mucositis is primarily oral > ocular > genital in distribution, and can be severe
  • Body rash may involve palms and soles
  • Complications: dehydration, GIB, epiglottitis, blindness, pericardial effusion
  • Testing: PCR nasal wash/BAL; agglutination assays IgM/IgG
  • Treatment: azithromycin and supportive care; occasionally steroids; rarely IVIG
  • Unlike Stevens-Johnsons, prognosis is good.

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