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Monosodium glutamate
- Rapid onset 30 min and lasts about 1 hour
- May accompanied with headache & chest pain.
- No associated GI sx.
- History of eating Chinese fodd. AKA "Chinese restaurant syndrome"
Metabisulfites (Na sulfite, Na/K bisfulfite, Na/K metabisulfite, etc.)
- Food preservatives found in dried fruit, wine, molasses, sauerkraut, etc.
- Bronchospasm – asthma like, headache, mild hypotension can occur
- Most significant reaction in people with asthma/allergies
- History of trying to eat "healthy"
Tyramine reaction
- Mostly among patients taking MAO inhibitors
- Source of tyramine (food): fermented, pickled product, avocado, chocolate, etc.
Niacin
- Burning warm sensation to body
- Often used for sexual enhancement, elevated cholesterol and beating drug urine screens
Trichloroethylene
- Occupational exposure – AKA “Degreaser’s flush”
- Facial flushing, head pressure, lacrimation & blurred vision may occur
- Require several weeks of exposure prior to symptoms
Scrombroids
- Occurs after a “fish meal” (e.g. dark meat fish - tuna)
- Associated with GI symptoms (nausea, vomiting, diarrhea)
- Histamine related reaction due to poor refrigeration after catching fish.
Hydroxocobalamin
- Antidote for CN poisoning
- Skin become red after administration due to its color (red)