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Ketamine and RSI for pts p TBI
- Traditionally, Ketamine has been avoided for patients with traumatic brain injury; however, this may be unwarranted…
- Early after TBI, ICP is not usually elevated.
- Early after TBI there is a low blood flow state, and Ketamine can increase cerebral blood flow.
- As long as there is no obstruction to CSF flow, Ketamine will not increase ICP.
- Evidence now states that Ketamine can be neuroprotective because it blocks glutamine because of it NMDA antagonist properties.
- Ketamine also has antiepileptic properties (which improve pediatric TBI outcomes).
- End result, if a patient has TBI and there is no concern for obstruction to CSF drainage, then Ketamine can be a possible option for RSI.