Heredity & Phenotype Interaction (Heart) Study (HAPI)

Principal Investigator: Dr. Alan Shuldiner

This study was designed to better understand how genes interact with common lifestyle factors like stress and diet to contribute to heart disease. It was very successful – nearly 900 Amish volunteered for this study.  Analysis of the data is ongoing in Baltimore at the University of Maryland School of Medicine.  We have already discovered a number of gene variants that influence heart disease and other medically relevant traits such as cholesterol and glucose levels.