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Confocal Microscopy Facility

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CONTACT:

Thomas Blanpied, PhD

Thomas Blanpied, PhD

Director
Department of Physiology
Room 5-015, Bressler Research Building
tblanpied@som.umaryland.edu
410-706-4769

Joseph Ryan H. Mauban, PhD

Joseph Ryan H. Mauban, PhD

Confocal Core Manager
Room 523, Howard Hall
jmauban@umaryland.edu
410-706-6170

Shilpa Dilip Kumar

Shilpa Dilip Kumar, PhD

Assistant Professor
Room 584, Howard Hall
SDKumar@som.umaryland.edu

410-706-0859

Yajie Liang

Yajie (Kevin) Liang, MB, PhD

Assistant Professor
Department of Diagnostic Radiology and Nuclear Medicine
HSF III, Room L127 Y
yajie.liang@som.umaryland.edu

LOCATION:

Room 610, Health Sciences Facility l
685 West Baltimore Street
Baltimore, MD 21201

HOURS:

Monday through Friday
7:00am - 5:00pm

PHONE:

410-706-6170


Mission

The mission of the Confocal Microscopy Core is to provide researchers with access to state-of-the-art optical imaging technologies, expert technical support, and advanced image analysis resources that enable high-quality, reproducible biological research. The Core is committed to supporting a broad spectrum of scientific applications by offering cutting-edge microscopy platforms, and by providing comprehensive training in experimental design, sample preparation, image acquisition, image processing, and quantitative analysis to empower users to generate meaningful and publication-quality data. The Core strives to foster innovation, collaboration, and scientific rigor by assisting investigators in selecting appropriate imaging approaches, optimizing workflows, and implementing reproducible image analysis strategies. Through education, consultation, and access to advanced technologies, the Confocal Microscopy Core serves as a collaborative resource that accelerates discovery across diverse areas of biomedical and biological research.

Services

The Confocal Microscopy Core provides comprehensive imaging services and technical support to facilitate high-quality biological and biomedical research. The facility offers access to a wide range of advanced microscopy platforms, including laser scanning confocal, spinning disk, super-resolution, lightsheet, and multiphoton imaging systems, supporting applications in fixed and live-cell imaging, tissue imaging, developmental biology, neuroscience, and in vivo imaging. Core staff work closely with researchers to assist with experimental planning, selection of appropriate imaging modalities, fluorophore and labeling strategies, optimization of acquisition parameters, and implementation of advanced imaging techniques such as FRAP, FRET, photoactivation, spectral imaging, and time-lapse imaging. In addition to image acquisition support, the Core provides consultation and training in image processing, visualization, and quantitative image analysis using both commercial and open-source software platforms. The facility is dedicated to promoting rigorous, reproducible, and quantitative imaging workflows while providing training, educational workshops, and collaborative support to researchers across a broad range of disciplines.

The Core also includes a dedicated cell culture room equipped with an incubator, culture hood, and widefield fluorescence microscope to support the preparation and maintenance of cultured and live-cell samples prior to imaging experiments. In addition, the space is equipped to support the preparation of live animal samples for imaging applications.

Learn More

Equipment 

Explore the advanced imaging systems available within the Confocal Microscopy Core, including confocal, spinning disk, super-resolution, lightsheet, and multiphoton microscopes. Detailed specifications and imaging capabilities are provided for each instrument.

Applications

Discover the wide range of biological applications supported by the Core, from live-cell and tissue imaging to super-resolution, developmental biology, neuroscience, and quantitative fluorescence imaging.

Image Analysis

Learn about the image processing, visualization, and quantitative analysis tools available through the Core, including commercial and open-source software platforms for multidimensional microscopy data analysis.

Training and Core Policies

Access information on user training, instrument access requirements, scheduling procedures, data management, and facility policies designed to ensure safe and efficient use of Core resources.

Pricing

View the current hourly rates and service fees for microscope usage, training, assisted imaging sessions, and image analysis resources available through the Core.

Courses and Workshops

Explore educational opportunities offered by the Core, including hands-on bioimage analysis workshops, lecture series, and specialized training sessions in microscopy and quantitative imaging.

Learning Resources

Browse protocols and educational materials to support microscopy experiments, image acquisition, and reproducible image analysis workflows.

News and Announcements

Stay updated on new instrumentation, software availability, workshops, policy updates, maintenance schedules, and other important announcements from the Confocal Microscopy Core.

 

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