The UMB Biobank is equipped with advanced instrumentation that supports high‑quality biospecimen processing, long‑term storage, and data‑driven research. Our infrastructure is designed to uphold the highest standards of sample integrity, automation, and traceability.
Below is an overview of our core instrumentation and capabilities.
Automated Storage & Temperature‑Controlled Infrastructure
Hamilton Biorepository (BIOS) Automated Freezer System
Our state‑of‑the‑art Hamilton BIOS platform provides high‑capacity, ultra‑low‑temperature storage at –80°C, accommodating over 900,000 biospecimens. The robotic retrieval system minimizes freeze–thaw cycles and supports secure, efficient sample handling. Integrated barcode scanning ensures accurate chain‑of‑custody and real‑time inventory updates.
Cryogenic Vapor‑Phase Liquid Nitrogen (LN₂) Storage
For biospecimens requiring deep cryogenic preservation, the Biobank maintains vapor‑phase LN₂ storage systems (< –150°C). These units support the long‑term stability of PBMCs, viable cells, and sensitive derivatives while minimizing contamination risk associated with liquid immersion. Continuous monitoring and alarmed safety systems preserve specimen integrity in accordance with ISBER-aligned standards for quality management and storage practices.
High‑Throughput Nucleic Acid Extraction & Liquid Handling
Microlab chemagic STAR Liquid Handling System
✓ High-throughput DNA extraction
✓ Sample aliquoting
✓ Automated assay setup workflows using retrieved samples
Chemagic 360 Extraction System
The chemagic 360 provides robust magnetic‑bead–based DNA extraction with optimized protocols for blood, PBMCs, and other sample types.
