Nanofabrication and Characterization Core

Overview

The Nanofabrication and Characterization Core Labs provide state-of-the-art facilities, training and services to the UMB research community, collaborators, and industrial partners/users. These shared-user facilities provide direct access to specialized research equipment operated by expert staff with advanced degrees in science and engineering.

Strategically located within the CBOTH facilities and in downtown Baltimore, the Core Lab offers integrated solutions in nanoparticle synthesis, physico-chemical characterization, wet-chemistry support, drug release studies, stability studies, nanoparticle tracking analysis, and electrophoretic potential measurements. Our state-of-the-art capabilities will support rapid in vitro measurement of aqueous state synthetic (e.g. liposomes, gold nanoparticles) or biological nanoparticles (e.g. extracellular vesicles) through multiple physical parameters such as size, concentration, surface charge, and phenotype characteristics.

Capabilities

Services Offered

Nano-formulation/Synthesis Service

Self-assembly in aq. Media
Liposomes, micelles, LNPs
Unimolecular synthesis
Drug/CA encapsulation
Knowledge-based synthesis of nanostructured material

Nanoparticle Tracking Analysis

Zeta potential and surface charge analysis
Aggregation analysis
Chromophore detection
Viscosity measurement
Stability measurement – 60 days
Drug encapsulation, release assay – 72hr
Full blown synthesis and characterization
Full blown toxicity assays and NCL assay cascade
Time Resolved Nanoparticle Optical and Hyperspectral Microscopy
Confirming nanoparticles in food containment systems and textiles and biological systems
Evaluating nanoparticle characteristics
Characterizing functional groups on nanoparticles
Evaluating Nanorod Characteristics
Self-operated use of nanocore equipment