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These infections remain difficult to diagnose early and early diagnosis is key to limiting morbidity and mortality.
“The classic clinical signs and symptoms are rarely all present especially in early disease. Crepitus or gas in the soft tissues, while specific, is only present in approximately 10% of patients. More often, the presenting symptoms are nonspecific: fever, pain, induration, and edema. Pain out of proportion to examination is a more specific finding that may assist in differentiation of NSTI from cellulitis.”
References
Current diagnosis and management of necrotizing soft tissue infections: What you need to know
Bisgaard, Erika K. MD; Bulger, Eileen M. MD
Journal of Trauma and Acute Care Surgery 97(5):p 678-686, November 2024. | DOI: 10.1097/TA.0000000000004351