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Question
68 year-old man presents with a new-onset seizure. What's the diagnosis and what's in your differential diagnosis?

Answer
Ring-enhancing lesion
Differential diagnosis of a ring-enhancing lesion
| Neoplasm | Infectious | Neurologic |
| Primary brain tumor | Pyogenic Abscess | Multiple Sclerosis |
| Primary CNS lymphoma | Tuberculoma | Sarcoidosis |
| Metastatic disease | Syphilis | Vasculitis |
| Neurocysticercosis | Aneurysm | |
| Toxoplasmosis | Resolving hematoma | |
| Nocardiosis | Cerebral infarct | |
| Cyptococcocus | Post-op changes | |
| Aspergillosis |

References
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