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Question
Name three differential diagnoses based on the CXR below.
Answer
The diagnosis in this case is Non-Hodgkin lymphoma, but read below for more differentials.
Mediastinal Masses
The mediastinum is subdivided into the regions shown below. Here are some differential diagnoses based on region.
Anterior / Superior Mediastinum
- Superior vena cava syndrome
- Ascending Aortic aneurysm
- Lymphoma
- Thyroid tumor
- Parathyroid tumor
- Thymic masses / tumors
- Germ-Cell tumor
- Metastatic disease
Middle Mediastinum
- Lymphadenopathy
- Metastatic Disease
- Lymphoma
- Developmental cysts
- Pericardial effusion
- Foregut duplication
- Bronchogenic cyst
- Vascular enlargement
- Aortic aneurysm
Posterior Mediastinum
- Neurogenic tumors
- Peripheral nerves
- Sympathetic ganglia
- Paraganglionic tissue
- Esophageal tumors
- Carcinoma
- Diverticula
- Diaphragmatic (Bochdalek's) hernia
Congratulations to all the graduating residents, especially our own at the University of Maryland. I wish you all the best as you start your phenomenal careers!
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