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Question
64 year-old male with no past medical history presents complaining of chronic weight-loss and diffuse chest pain; CXR is shown below. What's the diagnosis, and what other disease(s) may present this way?
Answer
Answer: Sclerotic bone (osteoblastic) metastasis secondary to prostate cancer. The patient's CXR from 2 years prior is shown below for comparison.
Other malignancies associated with osteoblastic metastasis:
- Breast cancer
- Colon cancer (mucinous adenocarcinoma)
- Lymphoma
- Carcinoid
- Neuroblastoma
- Prostate cancer (#1 cause)
References
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