Please email us at CPDM@som.umaryland.edu for more information
Fruit Fly (Drosophila Melanogaster) Models
| Disease | Genotype | Note |
| Heart Disease | Hand-GFP | Best GFP marker for visualizing the fly heart |
| Heart Disease | Hand-Gal4 | Heart-specific Gal4 driver |
| Heart Disease | 4xHand-Gal4 | Strongest heart-specific Gal4 driver |
| Heart Disease | Hand-GFP, 4xHand-Gal4 | Strongest heart-specific Gal4 driver & heart marker |
| Heart Disease | UAS-WDR5-wt | Wildtype human WDR5 gene |
| Heart Disease | UAS-WDR5-K7Q | Congenital Heart Disease variant for WDR5 |
| Kidney Diseases | MHC-ANF-RFP | Fly nephrocyte functional marker |
| Kidney Diseases | MHC-ANF-RFP, Dot-Gal4 | Nephrocyte-specific Gal4 driver & nephrocyte functional marker |
| Kidney Diseases | UAS-COQ2-wt | Wildtype human COQ2 |
| Kidney Diseases | UAS-COQ2-S146N | Nephrotic Syndrome variant for COQ2 |
| Kidney Diseases | UAS-CD2AP-wt | Wildtype human CD2AP |
| Kidney Diseases | UAS-CD2AP-K301M | Nephrotic Syndrome variant for CD2AP |
| Kidney Diseases | UAS-NUP160-wt | Wildtype human NUP160 |
| Kidney Diseases | UAS-NUP160-E803K | Nephrotic Syndrome variant for NUP160 |
| Kidney Diseases | UAS- NUP160-R1173X | Nephrotic Syndrome variant for NUP160 |
| Blood Diseases | Hml-Gal4, UAS-GFP | Blood specific Gal4 driver plus GFP |
| Muscle Disease | Mef2-Gal4, UAS-RFP | Muscle-specific Gal4 driver plus RFP |
| Neurological Diseases | Elav-Gal4, UAS-GFP | Neuronal Gal4 driver plus GFP |
| Metabolic Diseases | FB-Gal4, UAS-GFP | Fat body-specific Gal4 driver & GFP |
| Metabolic Diseases | Tub-Gal4 | Ubiquitous Gal4 driver |
Zebrafish (Danio rerio) Models
| Disease | Genotype | Note | ||
| Heart Disease | cmlc2:GFP | Best GFP marker for visualizing the zebrafish heart | ||
| Heart Disease | rttn -/- | Model of dilated cardiomyopathy | ||
| Heart Disease | VU177 | Model of Conotruncal defects | ||
| Vascular Disease | fli:egfp | Best GFP marker for visualizing the zebrafish vasculature | ||
| Vascular Disease | vbg | Model of hemorrhagic telangiectasia type 2 | ||
| Signaling Reporter | OTM:dGFP | Reports wnt activity | ||
| Signaling Reporter | dusp6:dGFP | Reports FGF activity | ||
| Signaling Reporter | Her4:RFP | Reports Notch activity | ||
Human Induced Pluripotent Stem Cells (iPSC)
| Disease | iPSC name | Reprogramming method | Source | Sex of patient |
| Epilepsy | DEPC-29 | Sendai virus | F | |
| Epilepsy | DEPI-22 | Sendai virus | F | |
| Tuberous sclerosis complex epilepsy | TSP20-1 | Sendai virus | fibroblast | F |
| Tuberous sclerosis complex epilepsy | TSP 16-8 | episomal vector | fibroblast | M |
| Dilated cardiomyopathy | LViP-1 | episomal vector | Left ventricular cardiac fibroblast | M |
| Dilated cardiomyopathy | LViP-3 | episomal vector | Left ventricular cardiac fibroblast | M |
| Long QT type 1 | LCL-4 | episomal vector | EBV-immortalized Lymphoblastoid cell line | |
| Long QT type 1 | LCL-8 | episomal vector | EBV-immortalized Lymphoblastoid cell line |