Mass Spectrometry Center
ABOUT THE CENTER:
The Mass Spectrometry Center is an Organized Research Center emphasizing collaborative research.
The MSC Vision is to accelerate discovery by providing investigators, on campus and beyond, access to cutting-edge technologies in mass spectrometry.
The MSC Mission is to lead or integrate into research teams with the goal of conducting high quality analytical science, publishing novel research, and obtaining sustainable funding pertaining to biological, medical, and pharmaceutical science including drug discovery and drug development.
The Mass Spectrometry Center is located in Pharmacy Hall North (PHN) and provides state-of-the-art expertise, methodology, and instrumentation to the School of Pharmacy, surrounding UMB research community and beyond. The Mass Spectrometry Center also provides researchers the opportunity to perform and access sophisticated experiments by working closely in a true collaborative effort between faculty, students, and staff scientists.
Expertise and Experience:
The expertise and experience of the Center staff span a broad range of biomedical research, from basic biology and medicine to technology development and translational research, including, but not limited to:
- Chemical Biology
- Pharmaceutical Biology
- Cancer Biology
- Microbial Biology
- Infectious Disease
- Metabolic Disease
- Chronic Pain Research
- Quantitative Biosciences
- Drug Discovery and Drug Development
- Translational and Regulatory Sciences
- Nanotechnology
- Instrumentation
- Bioinformatics and Technology Development
The Center also supports collaborative efforts with researchers worldwide on various topics.
Services / Areas of Analysis / Capabilities:
The Mass Spectrometry Center offers analysis expertise and applications spanning various fields. More details can be found on the Mass Spectrometry Center website.
- Metabolomics
- Lipidomics
- Proteomics
- Quantitative Analysis of Metal Ions in Biological Systems/Materials
- Metallomics
- LC-MS/MS assay development
- Drug analysis and PK/PD
- Bioanalysis for clinical studies
- Chemical compound identification and structure elucidation
- Biomarker identification and characterization
- Mass Spectrometry Imaging (MSI)
- Hydrogen Deuterium Exchange Mass Spectrometry (HDX)
- Fast Photochemical Oxidation of Proteins (FPOP)
- Bioinformatics and Cheminformatics
We continue to develop new opportunities to assist internal investigators, as well as external academic and industrial partners. Analysis and rate inquires should be sent to massspec@rx.umaryland.edu.
All projects require a consultation to define project goals and options for analysis. Email massspec@rx.umaryland.edu to set up an appointment for a consultation about your project.
Note About Citations: Please acknowledge the Mass Spectrometry Center in publications or grant proposals as follows, "This work is supported in part by the University of Maryland Baltimore, School of Pharmacy Mass Spectrometry Center (SOP1841-IQB2014)."
Instruments:
For more information on instruments visit the Mass Spectrometry Center website.
The Mass Spectrometry Center at the University of Maryland School of Pharmacy maintains 20 state-of-the-art instruments:
- AB Sciex 6500+ QTRAP Hybrid Tandem Quadrupole - Linear Ion Trap Mass Spectrometer
- Advion expression-L Compact Mass Spectrometer
- Agilent 6560 IMS-QTOF mass spectrometer with 1290 UPLC
- Agilent 7700 Inductively Coupled Plasma Mass Spectrometer
- Bruker AmaZon X Ion Trap Mass Spectrometer
- Bruker SolariX ESI/MALDI-12T-ICR Mass Spectrometer
- Bruker UltrafleXtreme MALDI TOF/TOF Mass Spectrometer
- Thermo Q-Exactive HF Quadrupole Mass Spectrometer
- Thermo TSQ Altis Tandem Quadrupole Mass Spectrometer
- Thermo TSQ Altis Tandem Quadrupole Mass Spectrometer
- Thermo LTQ Orbitrap Fusion Lumos Athena Tribrid Mass Spectrometer
- Thermo LTQ Orbitrap Fusion Lumos Apollo Tribrid Mass Spectrometer
- Waters ACQUITY TQ-XS Tandem Quadrupole Mass Spectrometer
- Waters ACQUITY TQ-XS Tandem Quadrupole Mass Spectrometer
- Waters SYNAPT G2si HDMS Q-TOF Mass Spectrometer
- Waters SYNAPT G2S HDMS Q-TOF Mass Spectrometer
- Waters TQ-S Triple Quadrupole Mass Spectrometer
- Waters UPLCs - Various Configurations
- Waters Select Series Cyclic IMS
- Agilent 8900 tandem quadrupole ICP-MS
