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The following symptoms of phenytoin toxicity typically present initially, once plasma concentrations reach the listed levels below:
- Nystagmus (on lateral gaze, at 20 mcg/mL)
- Ataxia (at 30 mcg/mL)
- Dysarthria and lethargy (at over 40 mcg/mL)
Other associated symptoms include tremor, hyper-reflexia, nausea, and vomiting.