UMEM Educational Pearls

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Category

Author

Title: Currently Approved LMWH for Treatment of PE

Category: Vascular

Keywords: LMWH, PE, Pulmonary Embolism (PubMed Search)

Posted: 8/11/2008 by Rob Rogers, MD (Updated: 3/3/2026)

Currently Approved LMWHs for the Treatment of Acute PE:

Enoxaparin-1 mg/kg every 12 hours subcut
Tinzaparin 175 Units/kg once daily subcut
The pentasaccharide: Fondaparinux- at a dose of 5 mg for body weight <50 kg, 7.5 mg for 50-100 kg, and 10 mg for >100 kg, once daily

Make sure to monitor platelet counts regardless of agent chosen.

Konstantinides. Acute pulmonary embolism revisited. Heart. June 2008