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Mechanical Ventilation Pearls for Acute Ischemic Stroke
- Patients with an acute ischemic stroke (AIS) may require intubation for various reasons.
- Two main goals of mechanical ventilation in patients with an AIS are to maintain appropriate oxygen levels and tight control of PaCO2.
- In terms of oxygenation:
- Target normoxia
- Administer O2 if the SpO2 is < 94%
- Supplemental O2 is not recommended in non-hypoxic patients
- In terms of CO2:
- Target normocapnia
- Hypercapnia increases the risk of intracranial hypertension
- Hypocapnia can worsen cerebral perfusion
References
Robba C, et al. Mechanical ventilation in patients with acute ischemic stroke: from pathophysiology to clinical practice. Crit Care. 2019;23:388.