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- Approved for CAP and Skin/Skin structure infections
- “Fifth generation” cephalosporin- implies activity against MRSA, although has broad spectrum
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Resistance is expected to be limited, with the exception of VRE, and VSE (vanco resistant or sensitive enterococcus faecalis)
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Renally excreted
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Common side effects: diarrhea, nausea, headache
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Serious side effects: anaphylaxis, renal failure, hepatitis, seizure
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Low incidence of C. difficile
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Dose : 600 mg IV (over 1 hour) q12 hours X 5-7 days