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- second most common vasculitis of childhood
- leading cause of acquired heart disease in children
- usually in children <5years old
- year-round with clusters in spring and winter
- highest incidence in children of asian decent
- clinical diagnosis requires fever for at least 5 days and a minimum of 4 of the following:
- bilateral conjunctival injection without exudate
- rash (often macular, polymorphous with no vesicles, most prominent in perineum followed by desquamation
- changes in the skin of the lips and oral cavity (red pharynx, dry fissured lips, strawberry tongue)
- changes in the extremities (edema, redness of hands and feet followed by desquamation)
- cervical lymphadenopathy
References
MedStudy Corecurriculum,
Pediatrics Board Review, 2004