Publications
Selected Recent Laboratory Publications
Briscoe V and Davis SN. "Hypoglycemia in Type 1 Diabetes", Type 1 Diabetes in Adults: Principles and Practice. Ed. Serge Jabbour, Elizabeth A. Stephens. Assoc. Ed. Irl B. Hirsch, Satish Garg, Barry J. Goldstein, Matthew C. Riddle. 2007; (Chapter 11): 195-211.
Sandoval DA, Gong B and Davis SN. Antecedent Short-Term Central Nervous System Administration of Estrogen and Progesterone Alters Counterregulatory Responses to Hypoglycemia in Conscious Male Rats. American Journal of Physiology: Endocrinology and Metabolism. 2007; 6:E1511-6.
Sandoval D, Gong B and Davis SN. Forebrain and hindbrain effects of ethanol on counterregulatory responses to hypoglycemia in conscious rats. Metabolism. 2007; 12:1623-1628.
Shibao C, Gamboa A, Diedrich A, Ertl AC, Chen K, Byrne D, Garley G, Paranjape S, Davis SN and Biaggioni I. Autonomic contribution to blood pressure and metabolism in obesity. Hypertension. 2007; 49:27-33.
Briscoe V, Tate D, Davis SN. Type 1 diabetes : Exercise and hypoglycemia. Journal of Applied Physiology, Nutrition and Metabolism. 2007; 32:576-582.
Gustavson S, Sandoval D, Ertl AC, Bao S, Raj S, Davis SN. Stimulation of both type I and type II corticosteroid receptors blunts counterregulatory responses to subsequent hypoglycemia in healthy humans. American Journal of Physiology: Endocrinology and Metabolism, 2008; 294: E506-E512.
Ertl AC, Mann S, Richardson A, Briscoe VJ, Blair HB, Tate DB and Davis SN. Effects of oral carbohydrate on autonomic nervous system counterregulatory responses during hyper-insulinemic hypoglycemia and euglycemia. American Journal of Physiology: Endocrinology-Metabolism, 2008; 295(3):E618-E625.
Briscoe VJ, Ertl AC, Tate DB and Davis SN. Effects of selective serotonin reuptake inhibitors on counterregulatory responses to hypoglycemia in healthy man. Diabetes, 2008; 57(9):2453-2460. PMCID: PMC2518497
Briscoe VJ, Ertl AC, Tate DB, and Davis SN. Effects of the selective serotonin reuptake inhibitor, fluoxetine, on counterregulatory responses to hypoglycemia in individuals with T1DM. Diabetes, 2008; 57(12):3315-3322. PMCID: PMC2584138
Perkins JM, Davis SN. The renin-angiotensin-aldosterone system: a pivotal role in insulin sensitivity and glycemic control. Curr Opin Endocrinol Diabetes Obes. 15:147-52, 2008.
Perkins JM, Davis SN. Endocannabinoid system overactivity and the metabolic syndrome: prospects for treatment. Curr Diab Rep. 8:12-9, 2008.
Davis SN, Mann S, Briscoe VJ, Ertl AC, Tate DB. The effects of intensive therapy and antecedent hypoglycemia on counterregulatory responses to hypoglycemia in type 2 diabetes. Diabetes58: 701-709, 2009. PMCID: PMC2646069
Bao S, Briscoe VJ, Tate DB, Davis SN. Effects of different antecedent increases of plasma cortisol on counterregulatory responses during subsequent exercise in type 1 diabetes. Diabetes. 58(9):2100-8, 2009. PMCID: PMC2731524
Younk L, Tate D, Davis SN. Physical activity in adolescents with type 1 diabetes: is more better for glycemic control? Pediatr Diabetes. 2009 Jun;10(4):231-3. PMID: 19493246
Davis SN. Hypoglycemia: A New Approach to an Old Problem, News and Views Article: Managing Hypoglycemia in Adults: An Endocrine Society Clinical Practice Guideline to the Evaluation and Management of Adult Hypoglycemic Disorders. Cryer, P.E., Axelrod, L., Grossman, A., Heller, S.R., Montari, V.M., Seaquist, E.R., and Service, J.F. Nature Reviews Endocrinology. 5(5):243-245, 2009.
Davis SN. The counterregulatory response in action, how the first defense against hypoglycemia works. Hypoglycemia in Type 2 Diabetes: Current Controversies and Changing Practice - International Congress and Symposium Series-273, The Royal Society of Medicine Press, Ltd. 2010.
Hedrington M, Farmerie S, Ertl A, Tate D, Davis SN. The Effects of Antecedent GABAA Activation with Alprazolam on Counterregulatory Responses to Hypoglycemia in Healthy Man. Diabetes. 59(1). 2010.
Gogitidze N, Hedrington MS, Briscoe VJ, Tate DB and Davis SN. The effects of hypoglycemia on atherothrombotic balance in type 1 DM and healthy man. Diabetes Care. 2010 Jul;33(7):1529-35.
Gogitidze N, Tate DB, Turner AG, Perkins JM, Briscoe VJ, Gilliam JW and Davis SN. Effects of hypoglycemia on endothelial function and atherothrombotic balance in healthy man. Diabetes 58: A168-169, 2009.
Wang Z, Hedrington MS, Gogitidze Joy N, Briscoe VJ, Richardson MA, Younk L, Nicholson W, Tate DB, Davis SN. Dose-response effects of insulin glargine in type 2 diabetes. Diabetes Care. 2010 Jul;33(7):1555-60
Hedrington M, Briscoe, VJ, Tate DB, Younk LM, Davis SN. The effects of antecedent GABA A receptor activation on counterregulatory responses to exercise in healthy man. Diabetes 59:A319, 2010.
Perkins JM, Gogitidze N, Richardson A, Briscoe VJ, Gilliam J, Tate DB and Davis SN. Effects of acute hyperglycemia and hyperinsulinemia on endothelial function and atherothrombotic balance in type 2 diabetes (T2DM). Diabetes 59:A216, 2010.
Turner A, Davis I, Ertl A, Tate D, Davis S. The effects of insulin on islet cell hormone secretion in healthy man. Diabetes 59:A658, 2010.
Younk LM, Mikeladze M, Tate D, Davis SN. Exercise-related hypoglycemia in diabetes mellitus. Expert Rev Endocrinol Metab. 2011 Jan 1;6(1):93-108. PMID: 21339838
Younk LM, Davis SN. Hypoglycemia and vascular disease. Clin Chem. 2011 Feb;57(2):258-60. PMID: 20974800
Davis SN. Hypoglycemia. Harrison’s Principles of Internal Medicine. 18th Ed. Dan L. Longo, Anthony S. Fauci, Dennis L. Kasper, Stephen L. Hauser, J. Larry Jameson, Joseph Loscalzo. (Chapter 347).
Lamos EM, Younk L, Davis SN. Canagliflozin, an inhibitor of sodium glucose co-transporter 2, for the treatment of type 2 diabetes mellitus. Expert Opinion on Drug Metabolism and Toxicology. 2013; 9(6):763-75.
Davis SN, Tate D, Hedrington MS. Mechanisms of hypoglycemia and exercise-associated autonomic dysfunction. Transactions of the American Clinical and Climatological Association. 2014, 125:281-292. PMCID: PMC4112662
Lamos EM, Younk LM, Davis SN. Empagliflozin, a sodium glucose co-transporter 2 inhibitor, in the treatment of type 1 diabetes. Expert Opinion On Investigational Drugs. 2014; 23(6):875-82.
Younk LM, Lamos EM, Davis, SN. Cardiovascular Effects of Insulin. Expert Opinion on Drug Safety. 2014; 13(7):955-66.
Hedrington MS, Davis, SN. Discontinued drugs in 2013: Diabetes. Expert Opinion on Investigational Drugs. 2014; 23(12); 1703-11.
Hedrington MS and Davis SN. Ipragliflozin, a sodium-glucose cotransporter 2 inhibitor, in the treatment of type 2 diabetes. Expert Opin Drug Metab Toxicol. 2015; 11(4):613-23.
Hedrington MS, Davis SN. Sexual dimorphism in glucose and lipid metabolism during fasting, hypoglycemia and exercise. Front Endocrinol (Lausanne). 2015; 6:61.
Hedrington MS, Davis SN. The role of empagliflozin in the management of type 2 diabetes by patient profile. Ther Clin Risk Manag. 2015; 11:739-49.
Joy NG, Tate DB, Younk LM, Davis SN. Effects of acute and antecedent hypoglycemia on endothelial function and markers of atherothrombotic balance in healthy man. Diabetes. 2015, 64(7):2571-80.
Joy N, Tate D, Davis S. Counterregulatory Responses to Hypoglycemia Differ between Glimepiride and Glyburide in non-Diabetic Individuals.
Metabolism 2015, 64:729-737.
Hedrington M, Tate D, Younk L, Davis S. Effects of Antecedent GABA A receptor Activation on Counterregulatory Responses to Exercise in Healthy Man. Diabetes. 2015 Sep;64(9):3253-61. doi: 10.2337/db15-0212. Epub 2015 Apr 21.
Perkins J, Joy NG, Tate DB, Davis SN. Acute effects of hyperinsulinemia and hyperglycemia on vascular inflammatory biomarkers and endothelial function in overweight and obese humans. Am J Physiol Endocrinol Metab. 2015, 309(2):E168-76.
Davis IC, Randell J, Davis SN. Immunotherapies currently in development for the treatment of type 1 diabetes. Expert Opinion on Investigational Drugs. 2015; 24(10):1331-41.
Lamos EM, Younk LM, Davis SN. Concentrated Insulins: The New Basal Insulins. Therapeutics and Clinical Risk Management. 2016; 12:389-400.
Lamos EM, Younk LM, Tate DB, Davis SN. Pharmacokinetics and Pharmacodynamics of Insulin Glargine-Insulin Glulisine Basal-Bolus and Twice-Daily Premixed Analog Insulin in Type 1 Diabetes Mellitus Patients during Three Standardized Meals. Journal of Clinical & Translational Endocrinology. 2016 Volume 3; 14-20.
Hedrington MS, Mikeladze M, Tate DB, Younk LM, Davis, IC, Davis SN. Effect of Antecedent GABA A Receptor Activation on Counterregulatory Responses to Exercise in Individuals with Type 1 Diabetes. Diabetes. 2016 pii: db160207. [Epub ahead of print]
Joy N, Mikeladze M, Tate DB, Davis SN. Effects of Equivalent Sympathetic Activation during Hypoglycemia on Endothelial Function and Pro-Atherothrombotic Balance in Healthy Individuals and Obese Standard Treated Type 2 Diabetes. Metabolism. Under Revision. 2016.
Joy N, Perkins, J, Mikeladze M, Tate DB, Younk L, Davis SN. Comparative effects of acute Hypoglycemia and Hyperglycemia on Pro-Atherothrombotic Biomarkers and Endothelial Function in Non-Diabetic Humans. Journal of Diabetes and Its Complications. Under Revision 2016.