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Overview
The Precancer Genomics Lab is dedicated to understanding cancer at its earliest stages, even before it fully develops. The lab's research explores the intricate genomic landscape of precancerous cells and their microenvironment, seeking to identify vulnerabilities and unlock strategies for cancer interception and, ultimately, a future with less cancer.
What is Precancer Genomics?
Pre-cancer genomics research focuses on the genetic changes that occur in cells before they develop into full-blown cancer. It aims to understand the molecular and cellular processes that lead to the transformation of normal cells into precancerous and then cancerous states.
This research helps in identifying potential targets for early detection, prevention, and treatment of cancer.
Learn more on PubMed >
What are the Key Aspects of Precancer Genomics Research?
- Identifying specific mutations, copy number alterations, and other genomic changes that distinguish them from normal cells.
- Understanding the evolution of precancerous lesions over time, examining how the molecular changes evolve as they progress towards invasive cancer.
- Exploring how the surrounding environment (microenvironment) of precancerous cells influences their growth, survival, and progression.
- Developing methods for early detection and cancer prevention.
- Identifying potential drug targets and therapeutic interventions that could block or reverse the progression to cancer.
What are the Potential Outcomes of Precancer Genomics Research?
- Early detection of cancer
- Personalized cancer prevention strategies
- Targeted treatments for cancer
- Improved survival and quality of life for patients with cancer