Translational Research Laboratories

Located on the 9th floor of the Medical School Teaching Facility (MSTF) building on the medical school campus in downtown Baltimore, our group brings together clinician scientists and basic scientists who share a common interest in translational neuroscience research to improve the lives of those who suffer from mental illness. Our space includes molecular and cellular biology laboratories, areas devoted to behavioral pharmacology, as well as shared procedure space for conducting neuroscience research. 

Investigators

Todd D. Gould, MD

The long-term goal of my research encompasses conducting high quality translational research that will yield outcomes with tangible benefits to patients suffering from mood disorders. My lab uses molecular, cellular, and especially behavioral approaches to study the pharmacology of psychotropic medications in rodents with a particular focus on the development of improved animal models in psychiatry, the functional consequences of mood disorder susceptibility genes, and collaborative translational studies with both basic science and clinically focused research groups. Current experiments are focused on defining the molecular mechanisms whereby lithium ions exert their therapeutic effects, studies with mice that harbor of a knockout of the mood disorder susceptibility gene CACNA1C, and investigating the behavioral and potential therapeutic profile of a novel beta-estradiol prodrug.
See Dr. Gould's Faculty Profile