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Haseeb Zubair, PhD

Academic Title:

Assistant Professor

Primary Appointment:



670 W Baltimore Street

Phone (Primary):


Education and Training

2003-2006       B.Sc. Biochemistry, Aligarh Muslim University

2006-2008       M.Sc. Biochemistry, Aligarh Muslim University

2008-2012       Ph.D. Biochemistry, Aligarh Muslim University

2014-2020       Postdoctoral Fellow, University of South Alabama

2020-2021       Lead Researcher, 3D Genome Consortium, St. Jude Children's Research Hospital

Research/Clinical Keywords

Cancer: Molecular pathogenesis, tumor-stromal interaction, chemoresistance, Transplant: Operational Tolerance, ischemia-reperfusion injury, disease pathogenesis Overarching: single-cell/nuclei RNA sequencing, immunology, DNA methylation, epigenetics, genomics, non-invasive biomarkers

Highlighted Publications

Zubair H, Khan MA, Anand S, Srivastava SK, Singh S, Singh AP. Modulation of the tumor microenvironment by natural agents: implications for cancer prevention and therapy. Semin Cancer Biol2022 May;80:237-255doi: 10.1016/j.semcancer.2020.05.009. Epub 2020 May 26. Review. PubMed PMID: 32470379; PubMed Central PMCID: PMC7688484.
Hagiwara K, Wang Z, Zubair H, Easton J, Mulder HL, Ma X, Ness KK, Li Z, Mulrooney DA, Wilson DL, Yasui Y, Hudson MM, Robison LL, Zhang J. Accelerated clonal hematopoiesis in survivors of childhood cancer: A report for the St. Jude Lifetime Cohort Study [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 499.
Srivastava SK, Khan MA, Anand S, Zubair H, Deshmukh SK, Patel GK, Singh S, Andrews J, Wang B, Carter JE, Singh AP. MYB interacts with androgen receptor, sustains its ligand-independent activation and promotes castration resistance in prostate cancer. Br J Cancer2022 May;126(8):1205-1214doi: 10.1038/s41416-021-01641-1. Epub 2021 Nov 26. PubMed PMID: 34837075; PubMed Central PMCID: PMC9023474.

Acharya S, Anand S, Khan MA, Zubair H, Srivastava SK, Singh S, Singh AP. Biphasic transcriptional and post-transcriptional regulation of MYB by androgen signaling mediates its growth control in prostate cancer. J Biol Chem2022 Nov 18;:102725doi: 10.1016/j.jbc.2022.102725. [Epub ahead of print] PubMed PMID: 36410437.

Deshmukh SK, Srivastava SK, Zubair H, Khan MA, Singh AP, Singh S. Resistin Induces LIN28A-Mediated Let-7a Repression in Breast Cancer Cells Leading to IL-6 and STAT3 Upregulation. Cancers (Basel)2021 Sep 7;13(18)doi: 10.3390/cancers13184498. PubMed PMID: 34572725; PubMed Central PMCID: PMC8470467.

Zubair H, Patel GK, Khan MA, Azim S, Zubair A, Singh S, Srivastava SK, Singh AP. Proteomic Analysis of MYB-Regulated Secretome Identifies Functional Pathways and Biomarkers: Potential Pathobiological and Clinical Implications. J Proteome Res2020 Feb 7;19(2):794-804doi: 10.1021/acs.jproteome.9b00641. Epub 2020 Jan 27. PubMed PMID: 31928012; PubMed Central PMCID: PMC7700759.

Zubair H, Azim S, Srivastava SK, Ahmad A, Bhardwaj A, Khan MA, Patel GK, Arora S, Carter JE, Singh S, Singh AP. Glucose Metabolism Reprogrammed by Overexpression of IKK╬Á Promotes Pancreatic Tumor Growth. Cancer Res2016 Dec 15;76(24):7254-7264doi: 10.1158/0008-5472.CAN-16-1666. Epub 2016 Oct 20. PubMed PMID: 27923829; PubMed Central PMCID: PMC5161695.

Patton MC, Zubair H, Khan MA, Singh S, Singh AP. Hypoxia alters the release and size distribution of extracellular vesicles in pancreatic cancer cells to support their adaptive survival. J Cell Biochem2020 Jan;121(1):828-839doi: 10.1002/jcb.29328. Epub 2019 Aug 12. PubMed PMID: 31407387; PubMed Central PMCID: PMC6878126.


Professional Activity

2022-2025: Sterling Committee Member- Special Interest Group: Precision Medicine and Biomarkers in Liver Transplantation, International Liver Transplantation Society