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Guofeng Xie, MBBS, PhD

Academic Title:

Associate Professor

Primary Appointment:



22 South Greene Street, Rm N3W62

Phone (Primary):

(410) 328-5780


(410) 328-8315

Education and Training


1990   MBBS., Peking University School of Medicine, Beijing, China.

1996   PhD, Biochemistry and Molecular Biology, Louisiana State University Health Science Center, Shreveport, LA.

Post Graduate Education and Training

1996-1999                   Postdoctoral Fellow, Life Sciences Division, Los Alamos National Laboratory, Los Alamos, NM.

1/2002-12/2004           Internship and Residency, Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, AR.

1/2005-12/2007           Fellowship, Gastroenterology, University of Maryland School of Medicine, Baltimore, MD.


I am board certified in Internal Medicine and Gastroenterology. My clinical interests are in the areas of esophageal motility disorders and impedance-pH monitoring. My basic research is focused on colon cancer and I have been funded by K08 award from NIH and by the VA Merit program.

Research/Clinical Keywords

Esophageal motility disorders; GERD; Colon cancer

Highlighted Publications

1.  Xie, G., Peng, Z and Raufman, JP. Src-mediated aryl hydrocarbon and epidermal growth factor receptor cross-talk stimulates colon cancer cell proliferation. Am J Physiol, Am J Physiol, 302:G1006-15,2012.

2.  Peng, Z., Heath, J., Drachenberg C., Raufman JP and Xie, G. Cholinergic muscarinic receptor activation augments murine intestinal epithelial cell proliferation and tumorigenesis.  BMC Cancer, 13:204, 2013.

3.  Said, A., Raufman JP and Xie, G. The role of matrix metalloproteinases in colorectal cancer. Cancers, 6:366-375,2014. 

4.  Xie, G and Raufman, JP. The role of aryl hydrocarbon receptor in colon neoplasia. 2015. Cancers, 7: 1436-1446, 2015.