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Areck A. Ucuzian, MD, PhD

Academic Title:

Assistant Professor

Primary Appointment:

Surgery

Location:

UMMC S10B00

Phone (Primary):

410-328-5840

Fax:

410-328-0717

Education and Training

Professional Training

Fellowship - Vascular Surgery; University of Pittsburgh Medical Center; Pittsburgh, PA

Residency - General Surgery;Loyola University Medical Center; Maywood,IL

Education

Loyola University Chicago; Maywood, IL

Ph.D.; Cell Biology, Neurobiology, and Anatomy

Tufts University School of Medicine; Boston, MA

M.D.; Medicine

Cornell University, Arts and Sciences; Ithaca, NY

B.A.; Cell/Molecular Biology

Research/Clinical Keywords

Aortic Disease Carotid Artery Disease Diabetic Foot Wounds Dialysis Access Surgery Limb Preservation Venous Disease

Highlighted Publications

  1. Ucuzian AA, Bufalino DV, Pang Y, Greisler HP.  “Angiogenic Endothelial Cell Invasion into Fibrin is Stimulated by Proliferating Smooth Muscle Cell.”  Microvascular Research.  Nov 22; 90:40-7. Epub 2013 Jul 22.
  2. Gassman AA, Kuprys T, Ucuzian AA, Brey E, Matsumura A, Pang Y, Larson J, Greisler HP. “Three Dimensional 10% Cyclic Strain Reduces Bovine Aortic Endothelial Cell Angiogenic Sprout Length and Augments Tubulogenesis in Tubular Fibrin Hydrogels.” J Tissue Eng Regen Med. 2011 May; 5(5): 375-383. 
  3. Brewster LP, Ucuzian AA, Brey EM, Liwanag M, Samarel AM, Greisler HP. “FRNK Overexpression Limits the Depth and Frequency Of Vascular Smooth Muscle Cell Invasion in a Three-Dimensional Fibrin Matrix.” J Cell Physiol. 2010 Nov; 225(2): 562-568. 
  4. Ucuzian AA, Brewster LP, East AT, Pang Y, Gassman AA, Greisler HP. “Characterization of the Chemotactic and Mitogenic Response of SMCs to PDGF-BB and FGF-2 in Fibrin Hydrogels.” J Biomed Mater Res A. 2010 Sep; 94(3): 988-996.
  5. Pang Y, Wang X, Ucuzian AA, Brey EM, Burgess WH, Jones KJ, Alexander TD, Greisler HP. “Local Delivery of a Collagen-binding FGF-1 Chimera to Smooth Muscle Cells in Collagen Scaffolds for Vascular Tissue Engineering.” Biomaterials. 2010 Feb; 31(5): 878-885.
  6. Pang Y, Ucuzian AA, Matsumura A, Brey EM, Gassman AA, Husak VA, Greisler HP. “The Temporal and Spatial Dynamics of Microscale Collagen Scaffold Remodeling by Smooth Muscle Cells.” Biomaterials. 2009 Apr; 30(11): 2023-2031.

Research Interests

My current research interest involves the study of aortic aneurysm and dissection in both animal and human studies.  We are studying the role of the endocytic receptor LRP1 in mediating the processes which lead to arterial wall degeneration and thus aneurysm and dissection formation.  

Clinical Specialty Details

My clinical interests include the broad spectrum of vascular disease including open and endovascular treatments for peripheral arterial disease, venous disease, carotid disease, dialysis access, and aortic disease.  I have a special interest in coordinating multidisciplinary care for limb preservation in patients with peripheral vascular disease.

Awards and Affiliations

Heart and Vascular Surgical Services,

Vascular Surgery - Board Certified

Professional Activity

Society for Vascular Surgery, active member

American Heart Association, active member

Links of Interest

umm.edu/programs/heart-and-vascular/services/limb-preservation