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Kenichi Tanaka, MD

Academic Title:

Professor

Primary Appointment:

Anesthesiology

Administrative Title:

Division Head, Cardiothoracic Anesthesiology

Location:

UMMC, S8D

Phone (Primary):

(410) 328-0205

Fax:

(410) 328-3092

Biosketch

Dr. Tanaka has received his doctor of medicine degree from Keio University in Tokyo, Japan. He has completed the Anesthesiology residency at University of Pittsburgh Medical Center (1995-1998). He subsequently pursued a clinical fellowship at the Department of Anesthesiology, Emory University School of Medicine (1998-2000). He also obtained the Masters in the Science of Clinical Research from the Graduate School of Emory University (2006). He is a diplomate of the American Board of Anesthesiology (1999).

In 2014, Dr. Tanaka joined the faculty at the University of Maryland School of Medicine (UM SoM) as a professor, and director of Cardiovascular Anesthesiology at University of Maryland Medical Center (UMMC).

Dr. Tanaka currently serves on the editorial boards of British Journal of Anaesthesia (Associate Editor), Anesthesia & Analgesia (Senior Editor), and Journal of Cardiothoracic Vascular Anesthesia. 

Highlighted Publications

  1. Mazzeffi M, Chow JH, Tanaka K. Preoperative Erythropoietin in Cardiac Surgery: Evolving Standard of Care or Aggregation of Marginal Gain?  Anesth Analg. e110-e111. PMID: 31425250. 2019.
  2. Gleason TG, Argenziano M, Bavaria JE, Kane LC, Coselli JS, Engelman RM, Tanaka KA, Awad A, Sekela ME, Zwischenberger JB. Hemoadsorption to Reduce Plasma-Free Hemoglobin During Cardiac Surgery: Results of REFRESH I Pilot Study. Semin Thorac Cardiovasc Surg. pii: S1043-0679(19)30062-0. doi: 10.1053/ j.semtcvs.2019.05.006. 3-11. PMID: 31085219. 2019.
  3. Azran M, Tanaka KA. Interaction between Ticagrelor and CYP3A4 Inhibitor: Importance of P2Y12 Function Testing to Assess Platelet Recovery Before Surgery. J Cardiothorac Vasc Anesth. https://doi.org/10.1053/j.jvca.2019.05.004. 2019.
  4. Strauss E, Tanaka K, Mazzeffi M. HAS-BLED-A Canary in Cardiac Surgery Bleeding? J Cardiothorac Vasc Anesth. 33(6), 1607-1609. PMID: 30928287. 2019.
  5. Abuelkasem E, Mazzeffi MA, Henderson R, Wipfli C, Monroe A, Strauss ER, Chow JH, Tanaka KA. Clinical Impact of Protamine Titration-based Heparin Neutralization in Patients Undergoing Coronary Bypass Grafting Surgery. J Cardiothorac Vasc Anesth. 33(8):2153-2160. DOI: 10.1053/j.jvca.2019.01.026. PMID: 30737123. 2019.
  6. Bolliger D, Tanaka KA. Platelet Count and Function-Can We Kill Two Birds With an Ultrasound Wave? J Cardiothorac Vasc Anesth. 33(6):1599-1600. doi: 10.1053/j.jvca.2019.02.038. Epub 2019 Mar 4. PMID: 30928280. 2019.
  7. Strauss E, Tanaka K, Mazzeffi M. HAS-BLED-A Canary in Cardiac Surgery Bleeding? J Cardiothorac Vasc Anesth. 33(6):1607-1609. doi: 10.1053/ j.jvca.2019.02.046. Epub 2019 Mar 5. PMID: 30928287. 2019.
  8. Tanaka KA, Bharadwaj S, Hasan S, Judd M, Abuelkasem E, Henderson RA, Chow JH, Williams B, Mazzeffi MA, Crimmins SD, Malinow AM. Elevated Fibrinogen, von Willebrand factor, and Factor VIII Confer Resistance to Dilutional Coagulopathy and Activated Protein C in Normal Pregnant Women. Br J Anaesth. 122(6), 751-759. doi: 10.1016/j.bja.2019.02.012. PMID: 30916034. 2019.
  9. Henderson RA, Mazzeffi MA, Strauss ER, Williams B, Wipfli C, Dawood M, Taylor BS, Tanaka KA. Impact of Intraoperative High-volume Autologous Blood Collection on Allogeneic Transfusion During and After Cardiac Surgery: A Propensity Score-matched Analysis. Transfusion. 59(6):2023-2029. doi: 10.1111/trf.15253. Epub 2019 Mar 18. PMID: 30882929. 2019.
  10. Martucci G, Grasselli G, Tanaka K, Tuzzolino F, Panarello G, Schmidt M, Bellani G, Arcadipane A. Hemoglobin trigger and approach to red blood cell transfusions during veno-venous extracorporeal membrane oxygenation: the international TRAIN-ECMO survey. Perfusion. 34(1_suppl), 39-48. PMID: 30966906. 2019.
  11. Tanaka KA, McNeil J, Abuelkasem E. Clot Retraction: Lost in Interpretation? Anesth Analg. 128(4), e53-e54. PMID: 30768460. 2019.
  12. Mazzeffi MA, Tanaka K, Roberts A, Rector R, Menaker J, Kon Z, Deatrick KB, Kaczorowski D, Griffith B, Herr D. Bleeding, Thrombosis, and Transfusion With Two Heparin Anticoagulation Protocols in Venoarterial ECMO Patients. J Cardiothorac Vasc Anesth. 33(5), 1216-1220. PMID: 30181084. 2019.
  13. Gleason TG, Argenziano M, Bavaria JE, Kane LC, Coselli JS, Engelman RM, Tanaka KA, Awad A, Sekela ME, Zwischenberger JB. Hemoadsorption to Reduce Plasma Free Hemoglobin During Cardiac Surgery: Results of REFRESH I Pilot Study. Semin Thorac Cardiovasc Surg. pii: S1043-0679(19)30062-0. doi: 10.1053/j.semtcvs.2019.05.006. [Epub ahead of print]. PMID: 31085219. 2019.
  14. Mazzeffi M, Strauss E, Meyer M, Hasan S, Judd M, Abuelkasem E, Nandwani V, McCarthy P, Tanaka KA. Coagulation Factor Levels and Underlying Thrombin Generation Patterns in Adult Extracorporeal Membrane Oxygenation Patients. Analg Anesth. 129(3), 659-666. doi: 10.1213/ANE.0000000000004275. PMID: 31425204. 2019.
  15. Williams B, Henderson R, Reformato VS, Pham T, Taylor BS, Tanaka KA. Hemostasis Management of Patients Undergoing Emergent Cardiac Surgery After Ticagrelor Loading. Case Report. J Cardiothorac Vasc Anesth.  pii: S1053-0770(19)30581-6. doi: 10.1053/j.jvca.2019.06.028. [Epub ahead of print]. PMID: 31375405. 2019.
  16. Takeshita S, Tanaka KA, Sawa T, Sanda M, Mizobe T, Ogawa S. Whole Blood Point-of-Care Testing for Incomplete Reversal With Idarucizumab in Supratherapeutic Dabigatran. Anesth Analg. DOI:   · 10.1213/ANE.0000000000004419. [Epub ahead of print]. PMID: 31490820. 2019.
  17. McNeil J, Raphael J, Chow JH, Tanaka K, Mazzeffi MA. Antifibrinolytic Drugs and Allogeneic Transfusion In Pediatric Multi-Level Spine Surgery: A Propensity Score Matched Cohort Study. Spine. doi: 10.1097/BRS.0000000000003273. [Epub ahead of print]. PMID: 31574059. 2019.
  18. Hollander KN, Mondal S, Tanaka KA. Peer Review of Intraoperative Blood Utilization in the Cardiac Anesthesia Team - is the Grass Greener on the Other Side? Transfusion. 59(10), 3289-3290. PMID: 31595990. 2019.

Research Interests

Dr. Tanaka’s research focuses has mainly focused on coagulation management, blood-less surgery and transfusion as well as clinical outcomes in the setting of cardiovascular surgery. I have participated in both preclinical and clinical studies of novel agents that modulate coagulation, and coagulation monitoring devices. The main focus is to evaluate the dynamic balance of thrombin generation during liver transplantation, and after cardiopulmonary bypass (CPB). To this end, multi-modal approaches to coagulation assessments are utilized; viscoelastic coagulation monitoring devices, fluorogenic thrombin generation assay, flow chamber system, and computer simulation model.

Clinical Specialty Details

1: Blood Conservation in Cardiac Surgery; 2: Clinical Diagnosis and Management of Perioperative Coagulopathy

Community Service

Committee on Patient Blood Management for the Americal Society of Anesthesiologists

Lab Techniques and Equipment

1: Calibrated automated thrombin generation assay; 2: rotational thromboelastometry; 3: flow chamber system