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Nadia A. Sam-Agudu, MD

Academic Title:

Associate Professor

Primary Appointment:

Pediatrics

Additional Title:

Senior Technical Advisor, Pediatric HIV, Institute of Human Virology, and International Senior Technical Advisor, Pediatric and Adolescent HIV, Institute of Human Virology Nigeria

Location:

IHV, 454N

Phone (Primary):

410-706-1941

Fax:

410-706-1944

Education and Training

2005-2008 - Fellowship, Pediatric Infectious Diseases, University of Minnesota, Minneapolis.

2002-2005 - Residency in Pediatrics, University of Minnesota, Minneapolis.

1998-2002 - Medical School, Mayo Medical School, Rochester, Minnesota.

1995-1998 - B.A. with distinction, Interdisciplinary/African Studies, University of Virginia, Charlottesville, Virginia.

Biosketch

My interest and career path in infectious diseases are inextricably linked with my goal to improve the health status of children living in resource-limited settings. To date, international research and global health experiences in Ghana, Nigeria, Uganda, South Africa, and Peru have exposed me to different contexts in the prevention and treatment of pediatric infectious diseases. My earliest research experiences were in basic and translational research in the immunology of severe malaria, which have now transitioned into implementation research in HIV prevention and treatment.

I have served as IHV-Maryland’s Senior Technical Advisor for Pediatric and Adolescent HIV to the Institute of Human Virology Nigeria since 2010. In so doing, I have expanded both my research and public health expertise in HIV treatment and prevention. My overarching research goal is to conduct studies that generate impactful evidence for equitable and sustainable health system and policy changes. I have found Implementation Science methods to be well-suited to achieving this goal, especially in the resource-limited settings I am working in.

My implementation science and public health projects also provide excellent global-local educational opportunities for motivated students and trainees. These learners are exposed to the health system from the perspective of the populations of interest, and are also able to experience, first-hand, the implementation of research-in-context projects.

The underlying principle for all of my work is the establishment and maintenance of healthy lives for vulnerable children, in spite of the prevailing challenging conditions. My supportive working environments at the University of Maryland and abroad have enabled me to continue working on this principle.

Research/Clinical Keywords

Implementation science, global health, HIV, pediatrics, adolescent, infectious diseases, Africa.

Highlighted Publications

  1. Sam-Agudu NA, Ramadhani HO, Isah C, Erekaha S, Fan-Osuala C, Anaba U, Adejuyigbe EA, Charurat M. The Impact of Structured Mentor Mother Programs on Presentation for Early Infant Diagnosis Testing in Rural North-Central Nigeria: A Prospective Paired Cohort Study. J Acquir Immune Defic Syndr. 2017 Jun 1;75 Suppl 2:S182-S189. doi: 10.1097/QAI.0000000000001345. PubMed PMID: 28498188.
  2.  Sam-Agudu NA, Ramadhani HO, Isah C, Anaba U, Erekaha S, Fan-Osuala C, Galadanci H, Charurat M. The Impact of Structured Mentor Mother Programs on 6-Month Postpartum Retention and Viral Suppression among HIV-Positive Women in Rural Nigeria: A Prospective Paired Cohort Study. J Acquir Immune Defic Syndr. 2017 Jun 1;75 Suppl 2:S173-S181. doi: 10.1097/QAI.0000000000001346. PubMed PMID:  28498187. 
  3. Sam-Agudu NA, Paintsil E, Aliyu MH, Kwara A, Ogunsola F, Afrane YA, Onoka C, Awandare GA, Amponsah G, Cornelius LJ, Mendy G, Sturke R, Ghansah A, Siberry GK,  Ezeanolue EE. Building Sustainable Local Capacity for Global Health Research in West Africa. Ann Glob Health. 2016 Nov - Dec;82(6):1010-1025. doi: 10.1016/j.aogh.2016.10.011. PubMed PMID: 28314488.
  4. Sam-Agudu NA, Folayan MO, Ezeanolue EE. Seeking wider access to HIV testing for adolescents in sub-Saharan Africa. Pediatr Res. 2016 Jun;79(6):838-45. doi: 10.1038/pr.2016.28. Epub 2016 Feb 16. Review. PubMed PMID: 26882367.
  5. Sam-Agudu NA, Greene J, Opoka RO, Kazura JW, Boivin MJ, Zimmerman PA, Riedesel MA, Schimmenti LA, John CC.  TLR9 polymorphisms are associated with altered IFN-γ levels in children with cerebral malaria.  American Journal of Tropical Medicine and Hygiene 2010; 82(4): 548-555

Additional Publication Citations

Complete List of Published Work in MyBibliography: http://www.ncbi.nlm.nih.gov/m/pubmed/?term=Sam-Agudu

Research Interests

Using implementation science approaches to provide evidence for sustainable strategies for the prevention and control of pediatric infectious diseases of public health significance. Diseases of particular interest are malaria, HIV, and tuberculosis.

Clinical Specialty Details

I am fellowship-trained in clinical pediatric infectious diseases. My particular interests lie in children with community-acquired infections with severe/atypical presentations, and in children with congenital or acquired immune deficiencies including those undergoing treatments for malignancy.

Awards and Affiliations

2007 - Honorable Mention Young Investigator Award, American Society of Tropical Medicine and Hygiene (ASTMH)

Grants and Contracts

2016 - 2021   Ezeanolue, E, and Sam-Agudu N, multiple PIs. Eunice Kennedy Shriver National Institute of Child Health & Human Development, National Institutes of Health, 1R01HD089871-01. Adolescent Coordinated Transition (ACT) to Improve Health Outcomes among Nigerian HIV+ Youth. This implementation research study tests the effectiveness of a graduated transition period and organized support groups on retention, viral suppression, and mental health among Nigerian adolescents living with HIV who are transitioned from pediatric to adult care.

2012 - 2017   Sam-Agudu N, PI: WHO & Global Affairs Canada INSPIRE Research award, RPC 531: The Impact of Mother Mentor Programs on PMTCT Service Uptake and Retention at Primary Healthcare Facilities in Nigeria. This implementation research study evaluates the impact of structured peer support on Early Infant Diagnosis presentation and retention among Mother-Infant Pairs in rural Nigeria.

2014 - 2018    Sam-Agudu N, Project Director: International Community Access to Child Health (ICATCH) Grant: Support Groups for Nigerian Adolescents Living with HIV. This project seeks to provide adolescent-friendly continuity of care and adherence support for Nigerian adolescents living with HIV in Nigeria. 

Professional Activity

 

2008 - 2010       Attending and Consultant, Pediatric Infectious Diseases, Travel and Immigrant/Refugee Medicine, Sanford Children’s Hospital and Clinic, Fargo, North Dakota.

2008 - 2010       Clinical Assistant Professor, The University of North Dakota School of Medicine and Health Sciences, Department of Pediatrics.

2010 - present    Senior Technical Advisor, Pediatric and Adolescent HIV: Institute of Human Virology (IHV) of the University of Maryland School of Medicine and IHV-Nigeria.

2014 - present    Assistant Professor, University of Maryland School of Medicine, Division of Pediatric Immunology.

 

Links of Interest

Institute of Human Virology http://www.ihv.org/

Institute of Human Virology, Nigeria http://ihvnigeria.org/ihvnweb/webnew/

All In to End Adolescent AIDS http://www.unaids.org/en/resources/campaigns/all-in