Division Head, Geriatric Psychiatry; Acting Division Head, Adult Psychiatry
Director, Division of Geriatric Psychiatry, Adult Inpatient Service and Electroconvulsive Therapy Service
Education and Training
1977-1981, Miami University, BA, Philosophy
1985-1989, McGill University, MDCM
1989-1990, Johns Hopkins Bayview Medical Center, Internship
1990-1993, Johns Hopkins Hospital, Psychiatry Residency
1992, Maudsley Hospital, Old Age Psychiatry training
I am a psychiatrist who is certified in general adult psychiatry and geriatric psychiatry by the American Board of Psychiatry and Neurology. My clinical work mostly involves older adults and adult inpatients. Although I see patients with a variety of psychiatric problems, I am particularly interested in patients whose psychiatric problems are associated with medical or neurological disorders. I also consult on patients of any age who are considering electroconvulsive therapy (ECT), and I perform ECT at the University of Maryland Medical Center.
My current areas of research interest include: the mechanisms of action of ECT; brain energy metabolism in neuropsychiatric disorders, including bipolar disorder, schizophrenia, and major depression; white matter disease in neuropsychiatric disorders, and biological markers and novel treatments for neuropsychiatric disorders, including major depression, bipolar disorder and Alzheimer's disease.
old age, geriatric, electroconvulsive therapy, bioenergetics, mitochondrial disorders, white matter disease, Alzheimer's disease, dementia, neurocognitive disorders, bipolar disorder, major depression, vitamin B12
Regenold WT, Pratt M, Nekkalapu S, Shapiro PS, Kristian T, Fiskum G: Mitochondrial detachment of hexokinase 1 in mood and psychotic disorders: Implications for brain energy metabolism and neurotrophic signaling. J Psychiatr Res, 46 (1): 95-104, 2012.
Lachner C, Steinle N, Regenold WT: The Neuropsychiatry of Vitamin B12 Deficiency in the Elderly. J Neuropsychiatry Clin Neurosci, 24 (1): 5-15, 2012.
Klinedinst NJ and Regenold WT: A mitochondrial bioenergetic basis of depression. J Bioenerg Biomembr, 47(1-2):155-71, 2015.
Regenold WT, Noorani RJ, Piez D, Patel P: Nonconvulsive electrotherapy for treatment resistant unipolar and bipolar major depressive disorder: a proof-of-concept trial. Brain Stimul, 8(5):855-61, 2015.
Regenold WT, Blumenthal JB, Loreck DJ, Mordecai KL, Scarinzi G MS, Doddi SR, Adler L: Elevated plasma Aβ42 in cognitively impaired individuals taking ACE inhibitor antihypertensives. Am J Alzheimers Dis Other Demen, doi: 10.1177/1533317517707288, 2017