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Aldo T. Iacono, MD

Hamish S. and Christine C. Osborne Distinguished Professorship in Advanced Pulmonary Care

Academic Title:

Professor

Primary Appointment:

Medicine

Administrative Title:

Medical Director of the Lung Healing Program at the Shock Trauma Center

Location:

22 South Greene Street

Phone (Primary):

410-328-4351

Fax:

410-328-6992

Education and Training

  • Liceo Malpighi; Bologna, Italy, Pre-Medical Degree 1977-1979                                                
  • University of Bologna; Bologna, Italy,  MD 1979-1985
  • Winthrop University Hospital, Research Associate, 1986-1989
  • Caledonian Hospital Intern/Resident in Internal Medicine, 1986-1989
  • State University of New York at Downstate, Brooklyn,NY, 1989-1992
  • Stony Brook University Medical Care Medicine Center, Fellow, Pulmonary and Critical Care Medicine 1989-1992                                            

Biosketch

I have been working in the field of thoracic organ transplantation and advanced lung diseases throughout my career on a full-time uninterrupted basis since 1992. I am currently employed at the University of Maryland Medical Systems Hospital and previously at the University of Pittsburgh Medical Center. I have contributed to the clinical and scientific developments towards having both centers develop into major lung transplant programs in the US. Currently, I serve as the Medical Director of the Lung Transplant Program at the University of Maryland Medical Center. I am also a member of The Program in Lung Healing of the University Of Maryland School Of Medicine, which is located in the Maryland Shock Trauma Unit, in Baltimore, Maryland. The goal of this Program is bring together a multidisciplinary team to provide the best clinical care for patients with acute and chronic lung diseases, to carry out cutting edge research and to train future clinician-scientists in this area. Presently, the research program in lung transplantation at the University of Maryland is a multi-faceted research program and has collaborated with several major centers including Johns Hopkins University, University of Maryland School of Engineering, INOVA Medical Center in Virginia, the University of Pittsburgh and the NIH Clinical Centers and others.

My research interests have been dealing with clinical issues in advanced lung diseases and thoracic organ transplantation. I have been instrumental in the development of interventional bronchoscopic procedures, including novel diagnostic and therapeutic modalities using lasers and stents treat airway stenosis after lung transplant. Recently, I started an independent company (Aerea Corporation) with University of Maryland to develop and commercialize experimental medical devices to assist in cardio-pulmonary resuscitation of mass causality victims. Finally, in the 1990’s I carried out experimental studies on the use of aerosol delivery of cyclosporine as a method of local administration of immunosuppression to the transplanted lungs to reduce toxicities due to high systemic levels. Our team has translated this technique to clinical application in lung recipients. We have demonstrated that aerosolized cyclosporine reduces chronic rejection and improves survival in lung transplant recipients.

Research/Clinical Keywords

Pulmonary, Lung Transplant, Extracorporeal Membrane Oxygenation, ECMO, Pulmonary Fibrosis, Cystic Fibrosis, lung disease, aerosol cyclosporine

Awards and Affiliations

Hamish Osborne Distinguished Professorship January 9, 2017

  • Hamish Osborne Professorship June 4, 2015
  • Shock Trauma Hero Award April 27, 2013
  • Shock Trauma Gala, Baltimore Maryland
  • Article of the Year
    #1 2009-2011
    Awarded by International Society of Aerosol Medicine
    Holland, Netherlands
    June 28,2011

SuperDoctors

  • Pulmonary Critical Care 2010  Baltimore Washington DC and Northern Virginia
  • Pulmonary Critical Care 2011 Baltimore Washington DC and Northern Virginia
  • Pulmonary Critical Care 2012 Baltimore Washington DC and Northern Virginia
  • Pulmonary Critical Care 2013 Baltimore Washington DC and Northern Virginia
  • Patient’s Choice Award 2012
  • Marquis’ Who’s  Who in America
  • The Leading Physcians of the World Publication 2013

Grants and Contracts

05/2014-04/2019
Principal Investigator:  Aldo T. Iacono, M.D.: Effort 1%
Genomic Transplant Dynamics
NIH
Budget $381,024

2012-2016
Principal Investigator:  Aldo T. Iacono, M.D.
Aerosol Cyclosporine for chronic rejection
Agency Pari Pharmaceuticals
Budget $285,000

08/15/10-11/30/16
Principal Investigator:  Aldo T. Iacono, M.D.; Effort 1%
"Open Label Use of Inhaled Cyclosporine in Lung Transplant Recipients"
Pulmonary Fibrosis Foundation
Total:  $80,000

03/01/07-present
Principal Investigator:  Aldo T. Iacono, M.D.; Effort: 0%
"An Open Label Treatment Use of Cyclosporine Inhalation Solution (CIS) in  Lung Transplant Recipients"
APT Pharmaceuticals, Inc., # NCT00633373
Total Budget: None/compassionate use study / Ongoing study