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Jonathan Chow, MD

Academic Title:

Assistant Professor

Primary Appointment:

Anesthesiology

Administrative Title:

Critical Care Medicine Fellowship Program Director

Location:

UMMC, S11D20

Phone (Primary):

(410) 328-4946

Education and Training

Education

2004-2008: B.A., Psychology, Williams College

2008-2012: M.D., Albany Medical College

Post Graduate Training

2012-2013: Internship, University of Rochester, Strong Memorial Hospital

2013-2016: Residency, Anesthesiology, University of Maryland Medical Center

2015-2016: Chief Resident, Anesthesiology, University of Maryland Medical Center

2016-2017: Fellowship, Critical Care Anesthesiology, George Washington University Hospital

Professional Appointments

2017-Present:  Assistant Professor, Anesthesiology, University of Maryland School of Medicine

2017-2018: Associate Program Director, Critical Care Anesthesiology Fellowship

2018-Present: Program Director, Critical Care Anesthesiology Fellowship

Biosketch

Dr. Chow received his Doctor of Medicine degree from Albany Medical College in Albany, New York.  He completed his Anesthesiology residency at the University of Maryland Medical Center in 2016, and then subsequently pursued a fellowship in Critical Care Medicine at George Washington University from 2016-2017.  He is a diplomate of the American Board of Anesthesiology, has additional subspeciality certification in Critical Care Medicine, and is a Testamur of the National Board of Echocardiography for Special Competence in Basic Perioperative TEE.

In 2017, Dr. Chow joined the faculty at the University of Maryland School of Medicine as an Assistant Professor.  He currently works as an anesthesiologist and critical care physician in the Surgical Intensive Care Unit, and also specializes in liver transplant anesthesiology.  Since 2018, he has served as the Program Director for the Critical Care Anesthesiology Fellowship.

His research interests include the use of novel treatment methods for acute respiratory distress syndrome (ARDS), vasoplegic, and septic shock, as well as thromboelastography, trans-thoracic ultrasound, and damage control resuscitation.

Research/Clinical Keywords

Shock, sepsis, thromboelastography, liver transplantation, resuscitation, trans-thoracic ultrasound

Highlighted Publications

Chow JH, Khanna AK, Kethireddy S, Yamane D, Levine A, Jackson AM, McCurdy MT, Tabatabai A, Kumar G, Mazzeffi MA et al. Aspirin Use is Associated with Decreased Mechanical Ventilation, ICU Admission, and In-Hospital Mortality in Hospitalized Patients with COVID-19. Anesthesia and Analgesia. 2020.

Chow JH, Mazzeffi MA, and McCurdy MT. Angiotensin II for the Treatment of COVID-19-related Vasodilatory Shock. Anesthesia and Analgesia. 2020.

Chow JH, Mazzeffi MA, and McCurdy MT. Justification of the Safety and Efficacy of Angiotensin II for the Treatment of SARS-CoV-Induced Shock. Anesthesia and Analgesia. 2020.

Mazzeffi MA, Chow JH, and Tanaka KA. COVID-19 Associated Hypercoagulability: Manifestations, Mechanisms, and Management. Shock: Injury, Inflammation, and Sepsis: Laboratory and Clinical Approaches. 2020 (accepted, in-press).

Mazzeffi MA, Chow JH, Amoroso A, Tanaka KA. Revisiting the Protein C Pathway: An Opportunity for Adjunctive Intervention in COVID-19? Anesthesia and Analgesia. 2020.

Busse LW, Chow JH, McCurdy MT, Khanna KA.  COVID-19 and the RAAS – A Potential Role for Angiotensin II?  Critical Care. 2020.

Chow JH, Fedeles B, Richards JE, Tanaka KA, Morrison JJ, Rock P, Scalea TM, and Mazzeffi MA for the TROPIC-Trauma Investigators.  Thromboelastography Reaction-time Thresholds for Optimal Prediction of Coagulation Factor Deficiency in Trauma.  Journal of the American College of Surgeons.  2020.

Chow JH, Wallis M, Lankford AS, Chancer Z, Barth RN, Scalea JR, LaMattina JC, Mazzeffi MA, McCurdy MT.  Treatment of Renin-Angiotensin-Aldosterone System Dysfunction with Angiotensin II in High-Renin Septic Shock. Seminars in Cardiothoracic and Vascular Anesthesia. 2020.

Chow JH, Chancer Z, Mazzeffi MA, McNeil J, Sokolow MJ, Gaines TM, Reif MM, Trinh AT, Wellington IJ, Camacho JE, Brucker JJ, Tanaka KA, Ludwig S.  Impact of Pre-operative Platelet Count on Bleeding Risk and Allogeneic Transfusion in Multi-Level Spine Surgery. Spine. 2020.

Lankford AS, Chow JH, Jackson AM, Wallis M, Galvagno SM, Malinow AM, Turan OM, Menaker JA, Crimmins SD, Rector R, Kaczorowski D, Griffith B, Kon Z, Herr D, Mazzeffi MA. Clinical Outcomes of Pregnant and Postpartum Extracorporeal Membrane Oxygenation Patients. Anesthesia and Analgesia. 2020 (accepted, in-press).

Lankford A, Chow JH, Hendrickson E, Jung MS, Kodali B, Malinow A, Goetzinger K, Mazzeffi MA.  Five Year Trends in Maternal Cardiac Arrest in Maryland: 2013-2017. The Journal of Maternal-Fetal & Neonatal Medicine. 2020.

Mazzeffi, MA, Chow JH, Wu Z, and Tanaka KA. Understanding extracorporeal membrane oxygenation induced coagulopathy: many pieces to the puzzle.  Critical Care Medicine.  2020.

Chow JH, Strauss E, Mazzeffi MA. Angiotensin II and Vasoplegia in Cardiac Surgery: Paradigm Changer or Costly Contender? Journal of Cardiothoracic and Vascular Anesthesia. 2020.

Heavner MS, McCurdy MT, Mazzeffi MA, Galvagno SM, Tanaka KA, Chow JH. Angiotensin II and Vasopressin for Vasodilatory Shock: A Critical Appraisal of Catecholamine-Sparing Strategies.  Journal of Intensive Care Medicine. 2020.

Chow JH, Abuelkasem E, Sankova S, Henderson R, Mazzeffi MA, Tanaka KA. Reversal of Vasodilatory Shock: Current Perspectives on Conventional, Rescue, and Emerging Vasoactive Agents for the Treatment of Shock.  Anesthesia and Analgesia.  2020.

Wallis M, Chow JH, Winters ME, and McCurdy MT.  Angiotensin II for the Emergency Physician.  Emergency Medicine Journal.  2020.

Chow JH, Mazzeffi MA, and Tanaka KA.  Reply To: Don’t Forget to Take Your Vitamins – B12.  Anesthesia and Analgesia. 2020.

Levine AR, Chow JH, and McCurdy MT.  An Argument for Personalized Vasopressors in Septic Shock.  Critical Care Medicine. 2020.

Chow JH, Richards JE, Morrison JJ, Galvagno SM, Tanaka KA, Madurska MJ, Rock P, Scalea TM, and Mazzeffi MA. Viscoelastic Signals for Optimal Resuscitation in Trauma: Thresholds for Detecting Hypofibrinogenemia in Kaolin-Thromboelastography (VISOR study).  Anesthesia and Analgesia.  2019.

Coleman PJ, Nissen AP, Kim DE, Ainsworth CR, McCurdy MT, Mazzeffi MA, and Chow JH.  Angiotensin II in Decompensated Cirrhosis Complicated by Septic Shock.  Seminars in Cardiothoracic and Vascular Anesthesia.  2019.

Mazzeffi MA, Chow JH, Tanaka KA. Preoperative Erythropoietin in Cardiac Surgery: Evolving Standard of Care or Aggregation of Marginal Gain?  Anesthesia and Analgesia. 2019.

Evans A, McCurdy MT, Weiner M, Zaku B, and Chow JH.  Use of Angiotensin II for Post Cardiopulmonary Bypass Vasoplegic Syndrome.  Annals of Thoracic Surgery. 2018.

Chow JH, Galvagno SM, Tanaka KA, Mazzeffi MA, Chancer Z, Henderson R, McCurdy MT.  When All Else Fails: Novel Use of Angiotensin for Vasodilatory Shock.  Anesthesia and Analgesia Practice.  2018.

Chow JH, Khanna, A.  Life After Angiotensin II.  Chest Physician. 2018.

Chow JH, Lee K, Abuelkasem E, Udekwu OR, Tanaka KA.  Coagulation Management During Liver Transplantation: Use of Fibrinogen Concentrate, Recombinant Activated Factor VII, Prothrombin Complex Concentrate, and Antifibrinolytics.  Seminars in Cardiothoracic and Vascular Anesthesia.  2017.

Additional Publication Citations

Tabatabai A, Rabin J, Menaker J, Madathil R, Galvagno S, Menne A, Chow JH, Grazioli A, Herr D, Tanaka KA, Scalea T, Mazzeffi MA. Factor VIII and Functional Protein C Activity in Critically Ill Patients With COVID-19: A Case Series.  A&A Practice. 2020.

Mazzeffi MA, Petrick KM, Magder L, Greenwald BD, Darwin P, Goldberg EM, Bigeleisen P, Chow JH, Anders M, Boyd CM, Kaplowitz JS, Sun K, Terrin M, Rock P. High-Flow Nasal Cannula Oxygen in Patients Having Anesthesia for Advanced Esophagogastroduodenoscopy: HIGHFLOW-ENDO, a Randomized Clinical Trial. Anesthesia and Analgesia. 2020. 

Mazzeffi MA, Taneja M, Porter S, Chow JH, Jackson B, Fontaine M, Frank S, Tanaka KA. Anemia, sex, and race as predictors of morbidity and mortality after knee arthroplasty surgery. Transfusion. 2020.

Mazzeffi MA, Judd M Rabin J, Tabatabai A, Menaker JA, Menne A, Chow JH, Shah A, Henderson R, Herr D, Tanaka TA. Tissue Factor Pathway Inhibitor Levels During Veno-Arterial Extracorporeal Membrane Oxygenation in Adults. ASAIO Journal. 2020 (accepted, in-press).

Richards JE, Fedeles B, Chow JH, Morrison JJ, Renner C, Trinh AT, Schlee C, Koerner AK, Grissom TE, Betzold R, Scalea TM, Kozar RA. Is Tranexamic Acid Associated with Mortality or Multiple Organ Failure Following Severe Injury.  Shock. 2020.

Mazzeffi MA, Strauss, E, Meyer M, Hasan S, Judd M, Abuelkasem E, Chow JH, Nandwani V, McCarthy P, and Tanaka K. Coagulation factor levels and underlying thrombin generation patterns in adult extracorporeal membrane oxygenation patients.  Anesthesia and Analgesia. 2019.

Tanaka KA, Bharadwaj S, Hasan S, Judd M, Abuelkasem E, Henderson RA, Chow JH, Williams B, Mazzeffi MA, Crimmins SD, and Malinow AM. Elevated Fibrinogen, Von Willebrand Factor, and Factor VIII Confer Resistance to Dilutional Coagulopathy and Activated Protein C in Normal Pregnant Women.  British Journal of Anesthesia.  2019.

Abuelkasem E, Mazzeffi MA, Henderson R, Wipfli C, Monroe A, Strauss ER, Chow JH, and Tanaka KA. Clinical impact of protamine titration-based heparin neutralization in patients undergoing coronary bypass grafting surgery.  Journal of Cardiothoracic and Vascular Anesthesia. 2019.

McNeil JS, Raphael J, Chow JH, Tanaka KA, Mazzeffi MA.  Antifibrinolytic drugs and allogeneic transfusion in pediatric multi-level spine surgery: a propensity score matched cohort study.  Spine.  2019.

Henderson, R, Chow JH, Tanaka KA. A Bridge to Bloodless Surgery: Use of Hemoglobin-based Oxygen Carrier for Anemia Treatment and Autologous Blood Preservation during Redo Pulmonic Valve Replacement. Journal of Cardiothoracic and Vascular Anesthesia. 2018.

Deshpande SP, Chow JH, Odonkor P, Griffith B, Carr SR.  Misadventures of a Pigtail –Accidental Insertion of a Chest Tube into the Left Atrium during Interventional Radiology Guided Placement.  Anesthesia and Analgesia Practice.  2018.

Tanaka KA, Mazzeffi MA, Chow JH.  Transfusion of Aged Red Blood Cells in Liver Transplantation - Et tu, Brute?.  Anesthesia and Analgesia.  2018.

Chow JH, Mazzeffi MA, Tanaka KA.  Teaching an Old Dog New TRICS: Re-evaluating Transfusion Triggers in High-Risk Cardiac Surgery.  Journal of Thoracic Disease.  2018.

Chow JH and Galvagno S, “Monitoring”, Pocket ICU 2nd edition, Frendl G & Urman R (eds.), Lippincott, Williams, & Wilkins, 2016.

Clinical Specialty Details

Liver Transplant Anesthesiology

Critical Care Medicine

Awards and Affiliations

2020 U.S. News and World Report "Hospital Heroes"

In the News

U.S. News and World Report - Robots Assist COVID-19 Doctors

CBS News Detroit - Daily Covid-19 Minute: Could Adding Aspirin To Your Covid-19 Treatment Plan Make All The Difference?

CBS News Baltimore - New Study Finds Taking Aspirin Significantly Lowers Risk Of Complications, Death In COVID-19 Patients

Fox News - Hospitalized coronavirus patients who take daily aspirin have lower death risk, study finds

Medium - Aspirin May Treat Severe Covid-19 Disease, and That Tells Us Something Important

Baltimore Business Review - Technological Transformation: How Covid-19 spurred a digital revolution in hospitals

The Baltimore Sun - Daily aspirin use could lower coronavirus death risk, University of Maryland medical school study finds

PatientCareOnline - Aspirin Reduces COVID-19 Mortality: Investigator's Insights

The Daily Mail - Could Aspirin be the first over the counter treatment for coronavirus? Hospitalized patients already taking the drug daily were 47% less likely to die of COVID-19

Links of Interest