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Cardiovascular & Renal Physiology Research Group

Cardiomyocyte MaCellFaculty in the Department of Physiology are internationally recognized for their research into the cellular and molecular aspects of cardiovascular and kidney function. We employ an interdisciplinary approach, using molecular, cell biological, electrophysiological, transgenic, functional genomic and optical techniques to understand how the cardiovascular-renal system works. Many of our graduate students, post-doctoral fellows and faculty are focused on elucidating the mechanisms of human disease, including hypertension, heart failure, cardiac arrhythmias and inherited disorders of salt and water balance.

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  • Toni Antalis, membrane serine proteases
  • Robert Bloch, The structure and function of the membrane systems in muscle, and the effects of muscular dystrophy and other myopathies
  • Mordecai Blaustein, Mechanisms of calcium signaling
  • Steven Fisher, Regulation of gene expression in vascular smooth muscle in hypoxia and heart morphogenesis
  • John Hamyln, Endogenous ouabain and mechanisms of hypertension
  • Joseph P. Y. Kao, Molecular Mechanisms of Calcium signaling
  • W. Jon Lederer, Molecular models of cardiac dysfunction
  • Andrea L. Meredith, Regulation of sino-atrial node firing and in vivo modulation of heart rate
  • Shawn Robinson, Pathophyisology of hypertensive heart disease, heart failure
  • Alan Shuldiner, Molecular genetics of type 2 (adult) onset diabetes, obesity, and hypertension
  • Marc Simard, Cerebral circulation, stroke
  • Dudley Strickland, LDL receptor proteins in inflammation
  • Matthew Trudeau, The molecular specializations underlying ion channel function in potassium channels activated by voltage and cation channels activated by intracellular cyclic nucleotides
  • James Wade, Membrane traffic of epithelial transporters
  • W. Gil Wier, Calcium signaling in heart and vascular smooth muscle
  • Owen Woodward, Regulation of uric acid handling and secretion
  • Li Zhang, The role of leukocytes in adaptive immune responses and the development of atherosclerosis, myocardial infarction, and stroke
  • Guiling Zhao, How the IP3 receptor works in heart and smooth muscle