Diagnostic Radiology and Nuclear Medicine
Education and Training
- 2004 – 2007 Ph.D. Bioengineering, University of Illinois, Chicago, IL.
- 2001 – 2003 M.S. Bioengineering, University of Illinois, Chicago, IL.
- 1996 – 2000 B.Tech. Chemical Engineering, Institute of People’s Science & Technology, India
Dr. Dinesh Shukla is an Assistant Professor in the Department of Diagnostic Radiology and Nuclear Medicine. His research interests include:
- Functional Imaging (Functional MRI, PET and Magnetoencephalography for an improved understanding of brain function and connectivity utilizing their unique strengths of spatial and temporal resolution.)
- Diffusion-based Magnetic Resonance Imaging (Development and application of diffusion-based imaging technique for a better characterization of injury severity as well as neurodevelopmental disorders.)
- Pulse Sequence Programming (Development of spiral pulse sequences for high-resolution functional MRI and MR spectroscopy imaging.)
- Perfusion-based Magnetic Resonance Imaging (MR perfusion imaging to assess the potential of this technique for distinguishing malignant from benign tissue properties.)
- Magnetic Resonance Spectroscopy (To better understand the balance of excitation to inhibition in the cortex, which is controlled by the relative numbers and activities of glutamatergic and GABAergic neurons.)
- White Matter Tractography (To investigate microstructural changes in white matter fiber tracts in disease.)
- MRI-guided Focused Ultrasound (To transiently disrupt the blood brain barrier to promote antibody passage and develop therapies for neurotropic viral biothreat pathogens.)
Functional Connectivity; Diffusion Tensor Imaging; Brain Development; Neuro HIV
Bruce, H.A., Kochunov, P., Paciga, S.A., Hyde, C.L., Chen, X., Xie, Z., Zhang, B., Xi, H.S., O’Donnell P., Christopher, W., Schubert, C.T., Bellon, A., Ament, S.A., Shukla, D.K., Du, X., Rowland, L.M., O’Neill, H., Hong, L.E.: Potassium Channel Gene Associations with Joint Processing Speed and White Matter Impairments in Schizophrenia. Genes, Brain and Behavior 16:515-521,2017.
Kochunov P., Rowland L.M., Fieremans E., Veraart J., Jahanshad N., Eskandar G., Du X., Muellerklein F., Savransky A., Shukla D.K., Sampath H., Thompson P.M., Hong L.E.: Diffusion-weighted Imaging Uncovers Likely Sources of Processing-speed Deficits in Schizophrenia. Proc Natl Acad Sci (PNAS) 22: 13504-13509, 2016.
Savransky, A., Chiappelli J., Rowland L.M., Wisner, K., Kodi, P., Shi, Q., Shukla, D.K., Kochunov, P., Hong, L.E.: Fornix Structural Connectivity and Allostatic Load: Empirical Evidence from Schizophrenia Patients and Healthy Controls. Psychosomatic Medicine 79:770-776, 2017.