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Cynthia F. Bearer, MD, PhD, FAAP

Cobey Chair in Neonatology

Academic Title:

Professor

Primary Appointment:

Pediatrics

Administrative Title:

Division Head, Pediatric Neonatology; Associate Chair, Pediatrics

Location:

110 S. Paca Street, 8th floor

Phone (Primary):

(410) 328-6003

Fax:

(410) 328-1076

Education and Training

Degrees:

1972: B.A., Smith College, Mathematics, cum laude

1977: Ph.D., CaseWestern ReserveUniversity, Biochemistry, Dr. Kenneth Neet

1982: M.D., The Johns Hopkins University, Medicine

Internship and Residency:

1982-1983: Intern, Pediatrics, The Johns Hopkins Hospital, Baltimore, Maryland

1982-1984:Clinical Fellow in Pediatrics, The Johns Hopkins University School of Medicine

1983-1984: Resident, Pediatrics, The Johns Hopkins Hospital, Baltimore, Maryland

Fellowships:

1977-1978: Research Associate, Department of Cell Biology, BaylorCollege of Medicine, Dr. Lutz Birnbaumer

1978-1979: Postdoctoral Fellow, Department of Pharmacology, University of TexasMedicalSchool at Houston, Dr. Joseph Thompson

1984-1986: Fellow, Joint Program in Neonatology, Harvard Medical School, Dr. Alan L. Schwartz

1986-1987: Fellow, Division of Newborn Medicine, Washington University School of Medicine, Dr. Alan L. Schwartz

Postgraduate Training:

1990-1991: Postgraduate training, Occupational and Environmental Medicine, University of California San Francisco, Dr. Joseph LaDou

1992: Executive Leadership in Medicine, Levinson Institute, Harvard University

Biosketch

Cynthia F. Bearer, MD, PhD is the Mary Gray Cobey Professor of Neonatology with tenure, Chief of Neonatology and Associate Chair for Research, Department of Pediatrics, University of Maryland School of Medicine. She is the Editor-in-Chief of Pediatric Research.

Dr. Bearer completed a BA with honors in mathematics from Smith College; a Ph.D. in biochemistry from Case Western Reserve University; and an M.D. from The Johns Hopkins University School of Medicine. She became an Assistant Professor of Pediatrics at Case Western Reserve University in 1994 where she was promoted to Professor of Pediatrics with tenure. In 2008 she moved to University of Maryland School of Medicine to become the Mary Gray Cobey Professor of Neonatology. In 2009 she became Chief, Division of Neonatology and in 2012 Associate Chair for Research.

She has published extensively on fetal and pediatric environmental health. Her research has received funding from NIH, CDC and U.S. EPA. She has established fatty acid ethyl esters as a biomarker for both in utero exposure to ethanol, and impact on neurocognitive outcomes. She holds a patent on this technology. Her laboratory is studying the impact of common solvents including ethanol on the development of the cerebellum using both cellular and animal models. She is currently funded by the NIH/NICHD to study the impact of bilirubin and hypoxic ischemic injury on lipid rafts. She is a frequently invited speaker nationally and internationally.

She has published extensively in the scientific literature: 8 book chapters, and 70 peer reviewed articles.  Dr. Bearer is Editor-in-Chief of the journal, Pediatric Research. She is a member of the American Pediatrics Society and the Society for Pediatric Research. She has served on the Committee to Evaluate Children’s Health of the National Academy of Science. She is past President of the Fetal Alcohol Syndrome Study Group. She has served on the Scientific Advisory Board for the U.S. EPA. She is a Smith College Gold Medalist.

Highlighted Publications

Milstone AM, Bamford P, Aucott S, Tang N, White KR,  Bearer CF.  Chlorhexidine inhibits L1 cell adhesion molecule mediated neurite outgrowth in vitroPediatr Res 2014 Jan;75(1-1):8-13. PMID: 24126818

Tang N, Bamford P, Jones J, He M, Kane MA, Mooney SM, Bearer CF.  Choline partially prevents the impact of ethanol on the lipid raft dependent functions of L1 cell adhesion molecule.  Alcohol Clin Exp Res 2014 Nov;38(11):2722-30. PMID: 25421509

Min MO, Singer LT, Minnes S, Wu M, Bearer CF.Association of fatty acid ethyl esters in meconium and cognitive development during childhood and adolescence. J Pediatr. 2015 Apr;166(4):1042-7. doi: 10.1016/j.jpeds.2014.12.008. Epub 2015 Jan 13. PMID:25596105

Bearer CF, Wellmann KA, Tang N, He M, Mooney SM.  Choline ameliorates deficits in balance caused by acute developmental ethanol exposure.  Cerebellum 2015 Aug;14(4):413-20. doi: 10.1007/s12311-015-0691-7.

White KMR, Sabatino JA, He M, Davis N, Tang N, Bearer CF.  Toluene disruption of the functions of L1 cell adhesion molecule at concentrations associated with occupational exposures.  Pediatr Res 2016;80:170-1.

Additional Publication Citations

Bearer CF, Neet KE. Threonine inhibition of the aspartokinase-homoserine dehydrogenase I of E. coli: Threonine binding studies. Biochemistry 1978; 17:3512-3516.

Bearer CF, Neet KE. Threonine inhibition of the aspartokinase-homoserine dehydrogenase I of E. coli: Stopped-flow kinetics and the cooperativity of inhibition of the homoserine dehydrogenase activity. Biochemistry 1978; 17:3517-3522.

Bearer CF, Neet KE. Threonine inhibition of the aspartokinase-homoserine dehydrogenase I of E. coli: A slow transient and cooperativity of inhibition of the aspartokinase activity. Biochemistry 1978; 17:3523-3530

Birnbaumer L, Bearer C, and Iyengar R. A two-state model of an enzyme with an allosteric regulatory site capable of metabolizing the regulatory ligand. Simplified mathematical treatments of transient and steady state kinetics of an activator and its competitive inhibition as applied to adenylyl cyclases. J Biol Chem 1980; 255:3552-3557.

Bearer CF, Knapp RD, Kaumann AJ, Swartz TL, and Birnbaumer L. Iodohydroxybenzylpindolol: Preparation, purification, localization of its iodine to the indole ring, and characterization as a partial agonist. Mol Pharmacol 1980; 17:328-338.

Rosenfeld GC, Strada SJ, Dial EJ, Bearer CF, and Thompson WJ. Histamine, cyclic nucleotides, and gastric parietal cell secretion. Adv Cyclic Nucleotide Res 1980; 12:255-266.

Bearer CF, Chang K, Rosenfeld GC, and Thompson WJ. Histamine stimulation of rat gastric parietal cell adenyl cyclase: Modulation by guanine nucleotides. Arch Biochem Biophys 1981; 207:325-336.

Gropper R, Brandt RA, Elias S, Bearer CF, Mayer A, Schwartz AL, and Ciechanover A. The ubiquitin-activating enzyme, El, is required for stress-induced lysosomal degradation of cellular proteins. J Biol Chem 1991; 266:3602-3610.

Bearer CF, Gould S, Emerson R, Kinnunen P, and Cook CS. Fetal alcohol syndrome and fatty acid ethyl esters. Pediatr Res 1992; 31:492-495.

Warshaver Y, Bearer CF, and Belchis D. Osteogenesis Imperfecta and Ebstein's Anomaly: A case report with autopsy findings. Pediatr Pathol 1992; 12:425-431.

Bearer CF and Phillips R. Pediatric environmental health training: Impact on pediatric residents. Am J Dis Child 1992; 147:682-684.

Bearer CF. EMF and infant incubators. Arch Environ Health 1994; 49:352-354.

Bearer CF. Environmental health hazards: how children are different from adults. Future Child. 1995 Summer-Fall;5(2):11-26.

Bearer CF. How are children different from adults? Environ Health Perspect. 1995 Sep;103 Suppl 6:7-12.

Bearer CF and Emerson RK. Fetal activity of fatty acid ethyl ester synthases. ResearchCommunications in Alcohol and Substances of Abuse 1995; 16:189-194.

Crump C, Bearer CF, Paschal DC, Rodenbaugh D, and Etzel RA. Mercury exposure in high school chemistry teachers. Arch Environ Contam Toxicol 1996; 31:206-209.

Bearer CF, Emerson RK, Roitman ES, and Shackleton C. Maternal tobacco smoke exposure and persistent pulmonary hypertension of the newborn. Environ Health Perspect 1997; 105:202-206.

Horowitz RS, Dart RC, Jarvie DR, Bearer CF, and Gupta U. Placental transfer of N-acetylcysteine following human maternal acetaminophen toxicity. J Toxicol Clin Toxicol 1997; 35:447-51.

Landrigan PJ, Carlson JE, Bearer CF, Cranmer JS, Bullard RD, Etzel RA, Groopman J, McLachlan JA, Perera FP, Reigart JR, Robison L, Schell L, Suk WA. Children's health and the environment: a new agenda for prevention research.Environ Health Perspect. 1998 Jun;106 Suppl 3:787-94

Bearer CF.Biomarkers in pediatric environmental health: a cross-cutting issue.Environ Health Perspect. 1998 Jun;106 Suppl 3:813-6

Bearer CF, Lee S, Salvator AE, Minnes S, Swick A, Yamashita T and Singer L. Ethyl linoleate in meconium: A biomarker for prenatal ethanol exposure. Alcohol Clin Exp Res 1999; 23:487-493.

Claudio L, Bearer CF, Wallinga D. Assessment of the U.S. Environmental Protection Agency methods for identification of hazards to developing organisms. Part I: The reproductive and fertility testing guidelines. Am J Ind Med 1999; 35:543-553.

Claudio L, Bearer CF, Wallinga D. Assessment of the U.S. Environmental Protection Agency methods for identification of hazards to developing organisms. Part II: The developmental toxicity testing guidelines. Am J Ind Med 1999; 35:554-563.

Bearer CF, Swick AR, O’Riordan MA and Cheng G. Ethanol inhibits L1 mediated neurite outgrowth in postnatal day 6 cerebellar granule cells. J Biol Chem 1999; 274:13264-13270.

Bearer CF, O’Riordan MA, and Powers R. Lead exposure from blood transfusion to premature infants. J Pediatr 2000; 137:549-54.

Bearer CF. The special and unique vulnerability of children to environmental hazards. Neurotoxicology 2000: 21:925-934.

Bearer CF. L1 Cell Adhesion Molecule Signal Cascades: Targets for Ethanol Developmental Neurotoxicity. Neurotoxicology 2001;22:625-33.

Bearer CF. Mechanisms of brain injury: L1 cell adhesion molecule as a target for ethanol-induced prenatal brain injury.Semin Pediatr Neurol. 2001 Jun;8(2):100-7.

Gitterman BA, Bearer CF. A developmental approach to pediatric environmental health. Pediatr Clin North Am. 2001 Oct;48(5):1071-83.

Bearer CF. Developmental neurotoxicity. Illustration of principles.Pediatr Clin North Am. 2001 Oct;48(5):1199-213.

Bearer CF.Markers to detect drinking during pregnancy.Alcohol Res Health. 2001;25(3):210-8.

Nagy LE, Lakshman MR, Casey CA, Bearer CF. Ethanol and membrane protein trafficking: diverse mechanisms of ethanol action. Alcohol Clin Exp Res. 2002 Feb;26(2):287-93.

Bearer CF. Meconium as a biological marker of prenatal exposure. Ambul Pediatr, 2003;3:40-43.

Noland JS, Singer LT, Arendt RE, Minnes S, Short EJ, Bearer CF. Executive functioning in preschool-age children prenatally exposed to alcohol, cocaine, and marijuana. Alcohol Clin Exp Res. 2003 Apr;27(4):647-56.

Bearer CF, Linsalata N, Yomtovian R, Walsh M, Singer L. Blood transfusions: a hidden source of lead exposure. Lancet 2003;362(9380):332.

Bearer CF, Jacobson JL, Jacobson SW, Barr D, Croxford J, Molteno CD, Viljoen DL, Marais AS, Chiodo LM, Cwik AS. Validation of a new biomarker of fetal exposure to alcohol. J Pediatr 2003 Oct;143(4):463-9.

Moya J, Bearer CF, Etzel R. Children’s behavior and physiology and how it affects exposure to environmental contaminants. Pediatrics 2004;113(4 Suppl):996-1006.

Bearer CF, Santiago LM, O’Riordan MA, Buck K, Lee S, Singer LT. Fatty acid ethyl esters: Quantitative biomarkers for maternal alcohol consumption. J Pediatr 2005; 146:824-830.

Lanphear B, Bearer CF. Biomarkers in paediatric research and practice. Archives of Disease in Childhood, 2005;90:594-600.

Noland JS, Singer LT, Short EJ, Minnes S, Arendt RE, Kirchner HL, Bearer CF. Prenatal drug exposure and selective attention in preschoolers. Neurotoxicology and Teratology 2005;27:429-438.

Needleman HL, Reigart JR, Landrigan P, Sass J, Bearer C. Benefits and risks of pesticide testing on humans.Environ Health Perspect. 2005 Dec;113(12):A804-5.

Bearer CF, Stoler JM, Cook JD. Biomarkers of alcohol use in pregnancy. Alcohol Res Health, 2005;28:38-43.

Tang, N, O’Riordan MA, Farkas C, Lemmon V, Bearer CF. Ethanol inhibits L1 cell adhesion molecule activation of mitogen activated protein kinases. J Neurochem 2006; 96:1480-90.

Nock ML, O'Riordan MA, Tang N and Bearer CF. L1 cell adhesion molecule found in human CSF varies as a function of age. Experimental Neurology 2006;202:262-265.

Lindsley T, Miller MW, Littner Y, Bearer CF. Signaling pathways regulating cell motility: A role in ethanol teratogenicity? Alcohol Clin Exp Res 2006;30(8):1445-50.

Littner Y, Bearer CF. Detection of alcohol consumption during pregnancy-Current and future biomarkers. Neurosci Biobehav Rev. 2007;31(2):261-9.

Gubitosi-Klug R, Larimer CG, Bearer CF.L1 cell adhesion molecule is neuroprotective of alcohol induced cell death. Neurotoxicology, 2007;28:457-462.

Littner Y, Cudd TA, O'Riordan MA, Cwik A, Bearer CF. Elevated Fatty Acid Ethyl Esters in Meconium of Sheep Fetuses Exposed In Utero to Ethanol-A New Animal Model. Pediatr Res. 2008 Feb;63(2):164-8. Epub 2007 Dec 10.

Lai TT, Bearer CF. Iatrogenic environmental hazards in the neonatal intensive care unit. Clin Perinatol. 2008 Mar;35(1):163-81.

Peterson J, Kirchner HL, Xue W, Minnes S, Singer LT, Bearer CF. Fatty acid ethyl esters in meconium are associated with poorer neurodevelopmental outcomes to two years of age. J Pediatr. 2008 Jun;152(6):788-92. Epub 2008 Jan 10.

Bearer CF, Stefanak MA 3rd. Looking Ahead to a Tobacco Free Future (editorial). J Pediatr. 2009 Jan;154(1):4-5. Epub 2008 Nov 5.

Yeaney N, He M, Tang N, Malouf A, O'Riordan M, Lemmon V, Bearer CF. Ethanol inhibits L1 cell adhesion molecule tyrosine phosphorylation and dephosphorylation and activation of pp60src. J Neurochem 2009 Aug;110(3):779-90. Epub 2009 May 3.

Bearer C, Bailey S, Hoek J. Advancing alcohol biomarkers research. Alcohol Clin Exp Res 2010, Jun;34(6):941-5. Epub 2010 Apr 5.

Braun JM, Daniels JL, Poole C, Olshan AF, Hornung R, Bernert JT, Xia Y, Bearer C, Barr DB, Lanphear BP. A prospective cohort study of biomarkers of prenatal tobacco smoke exposure: the correlation between serum and meconium and their association with infant birth weight. Environ Health. 2010 Aug 27;9(1):53.

Gifford AE, Farkas KJ, Jackson LW, Molteno CD, Jacobson JL, Jacobson SW, Bearer CF. Assessment of benefits of a universal screen for maternal alcohol use during pregnancy. Birth Defects Res A Clin Mol Teratol 2010, Oct;88(10):838-46.

Gordon PV, Seidner SR, Davis JM, Schelonka R, Durand DJ, Segar J, Watterberg K, Gendricks-Munoz KD, Silverman, GA, Rozycki HJ, Padbury JF, Subramanian S, Rubin LP, Davidson D, Carlo W, Short BL, Richardson J, Bednarek FJ, Gross I, Nelin L, Oelberg DG, Bearer C, Finer NN, Sinkin RA, Bancalari E, Greenberg J, Ryan RM, Perlman JM, Bedrick AD, Kourembanas S, Savani RC, La Gamma, EF, Dhanireddy R, Waffern F, Campbell D, Lane R, Georgieff MK, Steinhorn RH, Edwards WH, Rowitch DH, Goldberg RN, Dirnberger DR, Arrington R, Horgan M, Konduri G, Hanna N, Burchfield D, Moore JJ, Milstein J, Pyati S, Kilbride H, Meadow W, Seri I, Kennedy KA, Bada HS, Pillers DM, Barkemeyer B, Holtzman IR, Palmer C, Cummings J, Gewolb I, Balaraman V, Aranda JV, Bhatia J, Sridhar S, Rehan V, Carlton DP, Shankaran S, Walsh M. Regarding Part IV of Recertification in Neonatology: A Consensus Perspective of 69 Academic Neonatology Section Heads, e-J Neonatol Res. 1:1, 2011.

Tang N, Farah B, He M, Fox S, Malouf A, Littner Y, Bearer CF. Ethanol causes the redistribution of L1 cell adhesion molecule in lipid rafts. J Neurochem 2011 Nov;119(4):859-67. PMID: 21884525

Witherspoon NO, Trousdale K, Bearer CF, Miller RL. The public health and policy implications of epigenetics and pediatric health research. Environ Health Perspect 2012 Oct;120(10):a380-1. PMID: 23026401

Littner Y, Tang N, He M, Bearer CF. L1 cell adhesion molecule signaling is inhibited by ethanol in vivo. Alcohol Clin Exp Res 2013 Mar;37(3):383-9. PMID: 23050935

Milstone AM, Bamford P, Aucott S, Tang N, White KR, Bearer CF. Chlorhexidine inhibits L1 cell adhesion molecule mediated neurite outgrowth in vitro. Pediatr Res 2014 Jan;75(1-1):8-13. PMID: 24126818

Bearer CF. How Mary Ellen Avery influenced my career as an investigator. Front Pediatr. 2014 Apr 24;2:20. eCollection 2014. PMCID:PMC4006020

Tang N, Bamford P, Jones J, He M, Kane MA, Mooney SM, Bearer CF. Choline partially prevents the impact of ethanol on the lipid raft dependent functions of L1 cell adhesion molecule. Alcohol Clin Exp Res 2014 Nov;38(11):2722-30. PMID: 25421509

Gifford A, Bearer CF. Universal screening programs for gestational exposures (invited editorial), J Pediatr. 2015 Mar;166(3):522-4.

Min MO, Singer LT, Minnes S, Wu M, Bearer CF.Association of fatty acid ethyl esters in meconium and cognitive development during childhood and adolescence. J Pediatr. 2015 Apr;166(4):1042-7. doi: 10.1016/j.jpeds.2014.12.008. Epub 2015 Jan 13. PMID:25596105

Bearer CF. A short history of FAEE (invited commentary). Alcohol Clin Exp Res 2015, Mar;39(3):413-5.

Bearer CF, Wellmann KA, Tang N, He M, Mooney SM. Choline ameliorates deficits in balance caused by acute developmental ethanol exposure. Cerebellum 2015 Aug;14(4):413-20. doi: 10.1007/s12311-015-0691-7.

Carrasco M, Rao SC, Bearer CF, Sundararajan S. Neonatal gabapentin withdrawal syndrome.Pediatr Neurol. 2015 Nov;53(5):445-7.

Falck AJ, Mooney S, Kapoor SS, White KM, Bearer C, El Metwally D. Developmental Exposure to Environmental Toxicants.Pediatr Clin North Am 2015 Oct;62(5):1173-97.

Sundarajan S, Blatz A, Dearborn D, Varnes A, Bearer C, El-Metwally D. Toxic metal contamination of banked blood designated for neonatal transfusion. J Clin Toxicol20155:267. Doi:10.4172/2161-0495.1000267.

Bearer CF, Molloy EJ. Expanding Research, Relevance and Reach. Pediatr Res2016 Jan;79(1-1):2.

White KMR, Sabatino JA, He M, Davis N, Tang N, Bearer CF. Toluene disruption of the functions of L1 cell adhesion molecule at concentrations associated with occupational exposures. Pediatr Res 2016;80:170-1.

Shah SI, Brumberg HL, Bearer CF. Toward Development of Evidenced-Based Quality Parameters: What Gets Counted and Who Gets Paid? Pediatr Res 2016;80:145-50.

Johnson J, Bracken R, Tamma PD, Aucott SW, Bearer C, Milstone AM. Trends in chlorhexidine use in US Neonatal intensive care units: Results from a follow-up national survey. Infect Control Hosp Epidemiol 2016 Jun 20:1-2. [Epub ahead of print] No abstract available.

Gifford A, Bearer C. Comment on Niemela and Colleagues (2016). Alcohol Clin Exp Res 2016;40:1607-8.

Clinical Specialty Details

Practice of Neonatology including ECMO, ventilator management, pre-op cardiac management, entubation, chest tube placement, neonatal resuscitation, management of extremely premature infants, management of complex congenital malformations, management of infants with hypoxic-ischemic encephalopathy.  Developmental assessment of infants and children up to 3 years of age.

Awards and Affiliations

PROFESSIONAL SOCIETY MEMBERSHIPS

1977-present               American Association for the Advancement of Science

1987-1994                    American Federation for Clinical Research

1990-present               AmericanAcademy of Pediatrics

1992-1994                   National Council of Juvenile and Family Court Judges

1992-1999                   Teratology Society

1992-present               Physicians for Social Responsibility

1992- 1999                  Society of Occupational and Environmental Health

1993-present               Research Society on Alcoholism

1993-present               Fetal Alcohol Syndrome Study Group

1995-present               Society for Pediatric Research

1996-present               AmericanAcademy of Pediatrics, Section on Perinatal Pediatrics

1999-present               Perinatal Research Society

2000-present               Society for Neuroscience

2005-present               American Pediatric Society

HONORS AND AWARDS:

1972                            Phi Beta Kappa

1972                            Graduated cum laudeSmithCollege

1978                            Awarded NIH Postdoctoral Research Fellowship #1 F32 HL 5873-01

1979-1980                   Awarded W. Barry Wood Student Research Fellowship, The JohnsHopkinsUniversitySchool of Medicine

1980                            Awarded Cystic Fibrosis Foundation Student Traineeship, #H0022-01

1985                            Awarded Farley Fellowship, The Children's Hospital, Harvard Medical      School

1991                            Nominated for Best Teacher Award, Housestaff, Children's Hospital Oakland

2003                            Distinguished Teacher Award, Pediatric Housestaff, Tod Children's Hospital

2001-2002                   Secretary, Fetal Alcohol Syndrome Study Group

2002-2003                   Treasurer, Fetal Alcohol Syndrome Study Group

2003-2004                   President, Fetal Alcohol Syndrome Study Group

2004                            Learning Fellow, UniversityCenter for Innovation in Teaching and Education, CWRU

2004-present               Listed in “Guide to America’s Top Pediatricians”

2005                            Elected to the American Pediatrics Society

2007                            Thomas H. Pauly Excellence in Neonatology Lectureship, University of Kentucky

2008-present               Endowed, Mary Gray Cobey Professor in Neonatology, UMB, MD

2009-present               Listed in “Best Doctors in America”

2009                            Mansdorfer Lectureship, MercyHospital, Baltimore, MD

2009-present               Chair, Board of Directors, Children’s Environmental Health Network

2011-present               Elected to Super Doctors of Washington DC, Baltimore and Northern Virginia

2013                            Survey advisor, 2013 Baltimore Magazine Top Doctors

2015                            Named 2015 Smith Gold Medalist, Smith College

2016                            Selected to be Editor-in-Chief, Pediatric Research, official journal of the societies of SPR, APS and European SPR. 

Grants and Contracts

2016   Title:                             Effects of Perinatal Hypoxia-Ischemia on the Developing Cerebellum With and Without Prior Inflammation

            Position:                      Multiple Principle Investigator, 15% effort

            Source                         NIH/NICHD 1P01HD085928-01A1

            Duration:                     5 years, 08/17/16 – 7/31/21

            Total Direct Costs:      $7,718,381

2016   Title:                             The Role of Lipid Rafts in Bilirubin Neurotoxicity

            Position:                      Principle Investigator, 10% effort      Bearer (PI)

            Source:                        NIH/NICHD 1R21HD085061-01A1

            Duration:                     2 years, 04/01/16 – 03/31/18

            Total Direct Costs:      $275,000

2014    Title:                            Environmental Factors in Fetal Alcohol Spectrum Disorder

            Position:                      Co-investigator, 5% effort      Mooney (PI)

            Source:                        NIH/NIAAA R01 AA022413

            Duration:                     5 years, 05/05/14 - 4/30/19

            Total Direct Costs:      $1,250,000

2013    Title:                            Interactive Effect of Environmental Exposures and Alcohol in the Navaho Birth Cohort

           Position:                       Co-investigator, 2% effort      Bhakreiva (PI)

            Source:                        NIH/NIAAA  1 R15 AA022242-01

            Duration:                     3 years, 9/1/13 – 8/31/16

            Total Direct Costs:      $302,056

2013    Title:                            Center for Infant and Child Loss

            Position:                      Principal Investigator, 0% effort

            Source:                        Maryland Department of Health and Mental Hygiene

            Duration:                     3 years, 7/1/16 – 6/30/19

            Total Direct Costs:      $180,000

In the News

Advocacy

Testimony, briefings, meetings:

Testified before the U.S. House Subcommittee on Labor, Health & Human Services, Education & Related Agencies, United States House Committee on Appropriations regarding appropriations for Fiscal Year 2015, March 25, 2014

Testified before the U.S. House Subcommittee on Labor, Health & Human Services, Education and Related Agencies regarding Appropriations for Fiscal Year 2011, May 12, 2010

Testified before the United States Senate Environment and Public Works Committee at hearing on children’s environmental health, March 17, 2010

Congressional briefing on Pediatric Environmental Health, hosted by the Bishop's Conference on Environmental Health and the National Association of Evangelicals, Nov 30, 2011 

Invited participant, NIEHS strategic planning process meeting, July and October of 2011.

Statements submitted for the record, docket comments, etc.:

Provided comments on chlorhexidine use in preterm infants at the Open Public Hearing (OPH) portionof the Nonprescription Drugs Advisory Committee,  Food and Drug Administration.  September 3, 2014.

Submitted statement to the Institute of Medicine regarding the design of the National Children’s Study (NCS), October 31, 2013

Submitted docket comments on the National Institute of Environmental Health Science‘s (NIEHS’) Draft Mission Statement, Draft Vision Statement, and Draft Strategic Pillars, February 2, 2012

Submitted docket comments on Docket ID No. EPA-HQ-OPP-2010-0197, regarding nanoscale materials in registered pesticide products, August 16, 2011

Submitted docket comments on Docket ID No. EPA-HQ-OAR-2009-0234  and Docket ID No. EPA-HQ-OAR-2011-0044, regarding the U.S. Environmental Protection Agency’s (EPA) proposed national standards for mercury, arsenic and other toxic air pollutants from power plants, June 30, 2011

Submitted statement to the U.S. Senate Subcommittee on Labor, Health & Human Services, Education & Related Agencies regarding US Department of Health & Human Services Appropriations for Fiscal Year 2012, May 20, 2011

Submitted statement to the U.S. Senate Subcommittee on Interior, Environment & Related Agencies Appropriations regarding EPA Appropriations for Fiscal Year 2012, April 29, 2011

Submitted statement to the U.S. Senate Interior, Environment & Related Agencies Appropriations Subcommittee regarding Appropriations for Fiscal Year 2011, April 19, 2010

Submitted statement to the U.S. House Interior, Environment & Related Agencies Appropriations Subcommittee regarding Appropriations for Fiscal Year 2011, March 19, 2010

Submitted comments to the EPA regarding the proposed Third Edition of America’s Children and the Environment (ACE3), April 19, 2010

Submitted docket comments on Docket ID No. EPA-HQ-OAR-2010-0712, regarding EPA’s draft “Healthy Indoor Environment Protocols for Home Energy Upgrades,” December 8, 2010

Community Service

Blue Water Baltimore - stream clean up

Central Maryland Beekeepers Association

Lab Techniques and Equipment

  • Immunoblots
  • Immunoprecipitations
  • Cell culture
  • Transfections
  • Animal models
  • Membrane biochemistry

Equipment:

Bearer Lab

  • 2 tissue culture incubators,
  • 2 laminar flow hoods,
  • 1 fume hood,
  • 20oC and -70oC freezers,
  • liquid nitrogen storage
  • compound and inverted microscopes
  • table top centrifuge
  • microfuges
  • thin layer chromatography chambers
  • vertical electrophoresis cells
  • electro-transfer apparatus
  • power supplies
  • refrigerated desktop centrifuge.

Shared Equipment and Facilities, Department of Pediatrics

  • Micro- and ultra-centrifuges
  • Autoclaves
  • Ice makers
  • FluorChem HDII image analysis system
  • Zeiss photomicroscope fitted with digital camera