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Lawrence W. Adler, MD

Academic Title:

Clinical Assistant Professor

Primary Appointment:

Psychiatry

Location:

22 S. Greene St., S12A08

Phone (Primary):

(410) 328-6637

Phone (Secondary):

(443) 621-6733

Fax:

(410) 328-2672

Education and Training

1971: B.S., Biochemistry, University of Maryland, College Park (Cum Laude)
1976: M.D., University of Maryland School of Medicine
1975-1976: Post-doctoral Research Associate, University of Maryland School of Medicine, Dept. of Biological Chemistry
1976-1979 Residency, Psychiatry, Sheppard-Pratt Hospital

Biosketch

Lawrence W. Adler, MD is Assistant Clinical Professor of Psychiatry (Geriatric) at the University of Maryland School of Medicine.

After earning his medical degree from the University of Maryland School Medicine in Baltimore, Dr. Adler conducted postdoctoral research in biological chemistry, publishing papers on membrane biology and active transport energetics. Dr. Adler served as a resident psychiatrist at Sheppard Pratt Hospital for three years.

Dr. Adler is board-certified in General Psychiatry and in Geriatric Psychiatry, and is a Certified Physician Investigator.

As a researcher, Dr. Adler has been an investigator and a co-investigator on over 100 clinical trials sponsored by the National Institute of Mental Health and many major pharmaceutical companies. Dr. Adler's current research efforts are focused on schizophrenia,;tardive dyskinesia, and Alzheimer's Disease and the epidemiology and neurobiology of suicide.

As an author, Dr. Adler has published papers on all aspects of psychiatry in journals such as the American Journal of Psychiatry, the British Journal of Psychiatry, the American Journal of Medical Genetics, and Archives of General Psychiatry.

Dr. Adler is a member of many societies and associations, including the Society for Neuroscience, Society for Biological Psychiatry, the International Society for CNS Clilical Trials and Methodology, the American Society of Clinical Psychopharmacology, the American Psychiatric Association, the Academy of Physicians in Pharmaceutical Research, the American Association for Geriatric Psychiatry and the College Internationale Neuro-Psychopharmacolique.

Research/Clinical Keywords

Geriatric Psychiatry Alzheimer's Disease Bioenergetics Suicide

Highlighted Publications

Pulver AE, Karayioorgou M, Wolyniec PS, Lasseter VK, Kasch L, Nestadt G, Antonarkis S, Housman D, Kazazian HH, Myers D, Adler L, Carpenter WT.  Sequential Strategy to Identify a Susceptibility Gene for Schizophrenia:  Report of Potential Linkage on Chromosome 22q12-q13.1Part 1 American Journal of Medical Genetics, 1994 March; 54: 36-43 (contributed to discussions of statistical approaches in linkage analysis and involved in diagnostic review and ascertainment)

Klein DF, Thase ME, Endicott J, Adler L., Glick I., Kalali A., Leventer S., Mattes J., Ross P., Bystristsky A.  Improving Clinical Trials:  American Society of Clinical Psychopharmacology Recommendations.  Archives of General Psychiatry, 2002 March; 59(3): 272-8

Hertzman M, Adler LW, Arlen B, Kern M. Lisinopril May Augment Antidepressant Response. Journal of Clinical Psychopharmacology, 25(2005) 618-620

Keefe RSE, Bilder RM, Harvey PD, Davis SM, Palmer BW, Gold JM, Meltzer HY, Green MF, Miller DD, Canive  JM, Adler LW, Mansschreck TC, Swartz M, Rosenheck R, Perkins DO, Walker TM, Stroup TS, McEvoy JP, Lieberman JA. Baseline Neurocognitive Deficits in the CATIE Schizophrenia Trial. Neuropsychopharmacology, advanced online publication 19 April 2006, 1-14

Adler LW, Regenold WT. Valproate-related hyperammonemia in older adult psychiatric inpatients, The Primary Companion to CNS Disorders, 2015, April; 17(2):doi:10.4088/PCC14141737

Additional Publication Citations

Hertzman M & Adler LW (2010) Clinical Trials in Psychopharmacology: A Better Brain 2nd edn. Wiley Press. West Sussex

Adler LW (2010) Genes, The Genome and Brain Tailored Drugs; In: Hertzman M & Adler LW (2010) Clinical Trials in Psychopharmacology: A Better Brain 2nd edn. Wiley Press. West Sussex pp.43-56

Adler LW. Mixed Bipolar Disorder Responsive to Lithium and Clonazepam. Journal of Clinical Psychiatry, 47 (1986) 49-50

Pulver AE, Carpenter WT#, Adler LW, McGrath, J.  Accuracy of the Diagnosis of Affective Disorders and Schizophrenia in Public Hospitals. American Journal of Psychiatry 1988 Feb; 145 (2) 218-220

Pulver AE, Brown CH. Wolyniec P, McGrath J, Adler, L, Carpenter WT, Childs B; Schizophrenia: Age at Onset, Gender, and Familial Risk. Acta Psychiatrica Scand 1990, Nov.82 (5) 344-5.

Pulver AE, Liang KY, Brown CH, Wolyniec P, McGrath, J, Adler, L, Tam D, Carpenter WT, Childs B. Risk Factors in Schizophrenia: Season of Birth, Gender, and Familial Risk. British J. Psychiatry 1992 Jan; 160: 65-71

Pulver AE, Liang KY, Wolyniec PS, McGrath J, Melton BA, Adler L, Childs B. Season of Birth of Siblings of Schizophrenic Patients.  British J. Psychiatry 1992 Jan; 160: 71-75

Samuels J, Nestadt G, Wolyniec W, Adler L, Liang K-Y, Pulver AE. Obsessive-compulsive symptoms in schizophrenia. Schizophr Res 1993 Apr; 9(2-3):139

Research Interests

  • Alzheimer's Disease
  • Schizophrenia: Neurocognitive Impairment
  • Tardive Dyskinesia
  • Alcohol Use Disorders
  • Clinical Trial Methodology

Clinical Specialty Details

  • Geriatric Psychiatry
  • Psychopharmacology
  • Treatment-Resistant Depression