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Pathology Biorepository (UMGCC)

The University of Maryland Greenebaum Cancer Center's (UMGCC)Pathology Biorepository Shared Service (PBSS) provides access to a consistently excellent quality of banked patient samples (tissue and other preparations) while maintaining patient confidentiality. PBSS also provides pathology, histology, and histotechnology consultation services to assist clinical investigators in the procurement, analyses, and clinicopathologic correlation of human tissue specimens.

The Pathology and Biorepository Shared Service was established by UMGCC in 2006 as a developing core. PBSS has both the unique advantage of the long-standing expertise gained under the well established relationship with the NCI as well as the advantage of
exsiting expertise and archives of the Pathology Department. PBSS is the only tissue bank shared service for specimens removed at
surgery on the campus. We have an integrated relationship with the Anatomic Pathology Department, which is essential for obtaining well-characterized tissue samples as well as for pathology and histology expertise.

Frozen tissue archives of PBSS consist of more than 7,000 frozen tumor samples, 5,900 of which are paired with normal tissue from the same patient, and more than 22,000 frozen lymphocyte, red cell, plasma, and serum samples.

Olga Ioffe, MD
7-016, Bressler Research Building
655 West Baltimore Street
Baltimore Maryland, 21201

Ashley Cellini, P.A. (ASCP)
Pathologist Assistant and Project Management

Kim Tuttle, H.T. (ASCP)

Services We Offer

Tissue Procurement and Processing Services

  • Blood, bone marrow and fluid processing
  • Track surgeriesExpedite processing and banking of excess tissues and tumors, including cells and fluids
  • Program/investigator specific procurement and processing (freeze, fix, tissue culture, fractionation)
  • Quality control

Translational Research Support

  • Histology
  • Tissue processing and embedding
  • Sectioning and staining
  • Tissue Microarray construction
  • Immunohistochemistry: antibody work-up, control tissues, automated processing
  • Image analysis: quantitative IHC (ACIS Chromavision,Aperio digital IHC and TMA software)
  • Pathology consultation/interpretation
  • Linkage of archived tissue to clinical data
  • Assist with IRB issues