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Faculty and Staff Publications


(144 articles: 01/01/2015 – 12/31/2015)

Skovira JW, Kabadi SV, Wu J, Zhao Z, DuBose J, Rosenthal RE, Fiskum G, Faden AI. Simulated Aeromedical Evacuation Exacerbates Experimental Brain Injury. J Neurotrauma. 2015 Nov 23. [Epub ahead of print] PMID: 26593382 [PubMed - as supplied by publisher]

Wu J, Sabirzhanov B, Stoica BA, Lipinski MM, Zhao Z, Zhao S, Ward N, Yang D, Faden AI. Ablation of the transcription factors E2F1-2 limits neuroinflammation and associated neurological deficits after contusive spinal cord injury. Cell Cycle. 2015 Dec 2;14(23):3698-712. doi: 10.1080/15384101.2015.1104436. PMID: 26505089 [PubMed - in process]

Kumar A, Alvarez-Croda DM, Stoica BA, Faden AI, Loane DJ. Microglial/Macrophage Polarization Dynamics following Traumatic Brain Injury. J Neurotrauma. 2015 Dec 29. [Epub ahead of print] PMID: 26486881 [PubMed - as supplied by publisher]

Sabirzhanov B, Stoica BA, Zhao Z, Loane DJ, Wu J, Dorsey SG, Faden AI. miR-711 upregulation induces neuronal cell death after traumatic brain injury. Cell Death Differ. 2015 Oct 16. doi: 10.1038/cdd.2015.132. [Epub ahead of print] PMID: 26470728 [PubMed - as supplied by publisher]

Kabadi SV, Stoica BA, Zimmer DB, Afanador L, Duffy KB, Loane DJ, Faden AI. S100B inhibition reduces behavioral and pathologic changes in experimental traumatic brain injury. J Cereb Blood Flow Metab. 2015 Dec;35(12):2010-20. doi: 10.1038/jcbfm.2015.165. Epub 2015 Jul 8. PMID: 26154869 [PubMed - in process]

Faden AI, Wu J, Stoica BA, Loane DJ. Progressive inflammation-mediated neurodegeneration after traumatic brain or spinal cord injury. Br J Pharmacol. 2015 May 4. doi: 10.1111/bph.13179. [Epub ahead of print] PMID: 25939377 [PubMed - as supplied by publisher]

Lakkaraju SK, Mbatia H, Hanscom M, Zhao Z, Wu J, Stoica B, MacKerell AD Jr, Faden AI, Xue F. Cyclopropyl-containing positive allosteric modulators of metabotropic glutamate receptor subtype 5. Bioorg Med Chem Lett. 2015 Jun 1;25(11):2275-9. doi: 10.1016/j.bmcl.2015.04.042. Epub 2015 Apr 20. PMID: 25937015 [PubMed - in process]

Stocchetti N, Taccone FS, Citerio G, Pepe PE, Le Roux PD, Oddo M, Polderman KH, Stevens RD, Barsan W, Maas AI, Meyfroidt G, Bell MJ, Silbergleit R, Vespa PM, Faden AI, Helbok R, Tisherman S, Zanier ER, Valenzuela T, Wendon J, Menon DK, Vincent JL. Neuroprotection in acute brain injury: an up-to-date review. Crit Care. 2015 Apr 21;19:186. doi: 10.1186/s13054-015-0887-8. PMID: 25896893 [PubMed - in process]

Lipinski MM, Wu J, Faden AI, Sarkar C. Function and Mechanisms of Autophagy in Brain and Spinal Cord Trauma. Antioxid Redox Signal. 2015 Aug 20;23(6):565-77. doi: 10.1089/ars.2015.6306. Epub 2015 Apr 28. PMID: 25808205 [PubMed - in process]

He X, Lakkaraju SK, Hanscom M, Zhao Z, Wu J, Stoica B, MacKerell AD Jr, Faden AI, Xue F. Acyl-2-aminobenzimidazoles: a novel class of neuroprotective agents targeting mGluR5. Bioorg Med Chem. 2015 May 1;23(9):2211-20. doi: 10.1016/j.bmc.2015.02.054. Epub 2015 Mar 6. PMID: 25801156 [PubMed - in process]

Loane DJ, Stoica BA, Faden AI. Neuroprotection for traumatic brain injury. Handb Clin Neurol. 2015;127:343-66. doi: 10.1016/B978-0-444-52892-6.00022-2. PMID: 25702227 [PubMed - in process]

Liu S, Sarkar C, Dinizo M, Faden AI, Koh EY, Lipinski MM, Wu J. Disrupted autophagy after spinal cord injury is associated with ER stress and neuronal cell death. Cell Death Dis. 2015 Jan 8;6:e1582. doi: 10.1038/cddis.2014.527. PMID: 25569099 [PubMed - indexed for MEDLINE]  

Faden AI, Loane DJ. Chronic neurodegeneration after traumatic brain injury: Alzheimer disease, chronic traumatic encephalopathy, or persistent neuroinflammation? Neurotherapeutics. 2015 Jan;12(1):143-50. doi: 10.1007/s13311-014-0319-5. Review. PMID: 25421001 [PubMed - in process]  

Zhao Z, Sabirzhanov B, Wu J, Faden AI, Stoica BA. Voluntary Exercise Preconditioning Activates Multiple Antiapoptotic Mechanisms and Improves Neurological Recovery after Experimental Traumatic Brain Injury. J Neurotrauma. 2015 Sep 1;32(17):1347-60. doi: 10.1089/neu.2014.3739. Epub 2015 May 7. PMID: 25419789 [PubMed - in process]

Skopin MD, Kabadi SV, Viechweg SS, Mong JA, Faden AI. Chronic decrease in wakefulness and disruption of sleep-wake behavior after experimental traumatic brain injury. J Neurotrauma. 2015 Mar 1;32(5):289-96. doi: 10.1089/neu.2014.3664. Epub 2014 Dec 17. PMID: 25242371 [PubMed - indexed for MEDLINE]

Grissom CK, Hirshberg EL, Dickerson JB, Brown SM, Lanspa MJ, Liu KD, Schoenfeld D, Tidswell M, Hite RD, Rock P, Miller RR 3rd, Morris AH; National Heart Lung and Blood Institute Acute Respiratory Distress Syndrome Clinical Trials Network. Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome*. Crit Care Med. 2015 Feb;43(2):288-95. doi: 10.1097/CCM.0000000000000715. PMID: 25599463 [PubMed - indexed for MEDLINE]

Harris AD, Fleming B, Bromberg JS, Rock P, Nkonge G, Emerick M, Harris-Williams M, Thom KA. Surgical site infection after renal transplantation. Infect Control Hosp Epidemiol. 2015 Apr;36(4):417-23. doi: 10.1017/ice.2014.77. PMID: 25782896 [PubMed - in process]

Mazzeffi M, Kassa W, Gammie J, Tanaka K, Roman P, Zhan M, Griffith B, Rock P. Preoperative Aspirin Use and Lung Injury After Aortic Valve Replacement Surgery: A Retrospective Cohort Study. Anesth Analg. 2015 Aug;121(2):271-7. doi: 10.1213/ANE.0000000000000793. PMID: 25993389 [PubMed - indexed for MEDLINE]

Bradley M, Bonds B, Dreizin D, Colton K, Shanmuganathan K, Scalea TM, Stein DM. Indirect signs of blunt duodenal injury on computed tomography: Is non-operative management safe? Injury. 2016 Jan;47(1):53-8. doi: 10.1016/j.injury.2015.10.003. Epub 2015 Oct 13. PMID: 26510408 [PubMed - in process]

Dezman ZD, Comer AC, Smith GS, Narayan M, Scalea TM, Hirshon JM. Failure to clear elevated lactate predicts 24-hour mortality in trauma patients. J Trauma Acute Care Surg. 2015 Oct;79(4):580-5. doi: 10.1097/TA.0000000000000810. PMID: 26402531 [PubMed - indexed for MEDLINE]

Murthi SB, Scalea TM. Defining the space between life and death: Fatal critical illness. J Trauma Acute Care Surg. 2015 Sep;79(3):493-4. doi: 10.1097/TA.0000000000000734. No abstract available. PMID: 26307886 [PubMed - indexed for MEDLINE]

Zarzaur BL, Kozar R, Myers JG, Claridge JA, Scalea TM, Neideen TA, Maung AA, Alarcon L, Corcos A, Kerwin A, Coimbra R. The splenic injury outcomes trial: An American Association for the Surgery of Trauma multi-institutional study. J Trauma Acute Care Surg. 2015 Sep;79(3):335-42. doi: 10.1097/TA.0000000000000782. PMID: 26307863 [PubMed - indexed for MEDLINE]

Scalea JR, Bromberg J, Bartlett ST, Scalea TM. Mechanistic similarities between trauma, atherosclerosis, and other inflammatory processes. J Crit Care. 2015 Dec;30(6):1344-8. doi: 10.1016/j.jcrc.2015.07.024. Epub 2015 Jul 29. PMID: 26304513 [PubMed - in process]

Bruns BR, Tesoriero R, Narayan M, Klyushnenkova EN, Chen H, Scalea TM, Diaz JJ. Emergency General Surgery: Defining Burden of Disease in the State of Maryland. Am Surg. 2015 Aug;81(8):829-34. PMID: 26215249 [PubMed - indexed for MEDLINE]

Brenner M, Scalea TM, Stein DM. Lethal now or lethal later: The natural history of Grade 4 blunt cerebrovascular injury. Lauerman MH, Feeney T, Sliker CW, Saksobhavivat N, Bruns BR, Laser A, Tesoriero R, J Trauma Acute Care Surg. 2015 Jun;78(6):1071-4; discussion 1074-5. doi: 10.1097/TA.0000000000000654. PMID: 26151505 [PubMed - indexed for MEDLINE]

Bonds BW, Yang S, Hu PF, Kalpakis K, Stansbury LG, Scalea TM, Stein DM. Predicting secondary insults after severe traumatic brain injury. J Trauma Acute Care Surg. 2015 Jul;79(1):85-90; discussion 90. doi: 10.1097/TA.0000000000000698. PMID: 26091319 [PubMed - indexed for MEDLINE]

Dreizin D, Menaker J, Scalea TM. Extracorporeal membranous oxygenation (ECMO) in polytrauma: what the radiologist needs to know. Emerg Radiol. 2015 Oct;22(5):565-76. doi: 10.1007/s10140-015-1324-7. Epub 2015 Jun 6. PMID: 26047606 [PubMed - in process]

Bruns BR, DuBose J, Pasley J, Kheirbek T, Chouliaras K, Riggle A, Frank MK, Phelan HA, Holena D, Inaba K, Diaz J, Scalea TM. Loop versus end colostomy reversal: has anything changed? Eur J Trauma Emerg Surg. 2015 Oct;41(5):539-43. doi: 10.1007/s00068-014-0444-1. Epub 2014 Sep 4. PMID: 26037983 [PubMed - in process]

Harris DG, Koo G, McCrone MP, Weltz AS, Chiu WC, Sarkar R, Scalea TM, Diaz JJ, Lissauer ME, Crawford RS. Acute Kidney Injury in Critically Ill Vascular Surgery Patients is Common and Associated with Increased Mortality. Front Surg. 2015 Mar 9;2:8. doi: 10.3389/fsurg.2015.00008. eCollection 2015. PMID: 25806372 [PubMed]

Fox N, Schwartz D, Salazar JH, Haut ER, Dahm P, Black JH, Brakenridge SC, Como JJ, Hendershot K, King DR, Maung AA, Moorman ML, Nagy K, Petrey LB, Tesoriero R, Scalea TM, Fabian TC. Evaluation and management of blunt traumatic aortic injury: a practice management guideline from the Eastern Association for the Surgery of Trauma. J Trauma Nurs. 2015 Mar-Apr;22(2):99-110. doi: 10.1097/JTN.0000000000000118. PMID: 25768967 [PubMed - in process]

Murthi SB, Markandaya M, Fang R, Hong CM, Galvagno SM, Lissuaer M, Stansbury LG, Scalea TM. Focused comprehensive, quantitative, functionally based echocardiographic evaluation in the critical care unit is feasible and impacts care. Mil Med. 2015 Mar;180(3 Suppl):74-9. doi: 10.7205/MILMED-D-14-00374. PMID: 25747636 [PubMed - in process]

Holcomb JB, Tilley BC, Baraniuk S, Fox EE, Wade CE, Podbielski JM, del Junco DJ, Brasel KJ, Bulger EM, Callcut RA, Cohen MJ, Cotton BA, Fabian TC, Inaba K, Kerby JD, Muskat P, O'Keeffe T, Rizoli S, Robinson BR, Scalea TM, Schreiber MA, Stein DM, Weinberg JA, Callum JL, Hess JR, Matijevic N, Miller CN, Pittet JF, Hoyt DB, Pearson GD, Leroux B, van Belle G; PROPPR Study Group. Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial. JAMA. 2015 Feb 3;313(5):471-82. doi: 10.1001/jama.2015.12. PMID: 25647203 [PubMed - indexed for MEDLINE]

Brenner M, Hoehn M, Stein DM, Rasmussen TE, Scalea TM. Central pressurized cadaver model (CPCM) for resuscitative endovascular balloon occlusion of the aorta (REBOA) training and device testing. J Trauma Acute Care Surg. 2015 Jan;78(1):197-200. doi: 10.1097/TA.0000000000000484. No abstract available. PMID: 25539222 [PubMed - indexed for MEDLINE]

Fox N, Schwartz D, Salazar JH, Haut ER, Dahm P, Black JH, Brakenridge SC, Como JJ, Hendershot K, King DR, Maung AA, Moorman ML, Nagy K, Petrey LB, Tesoriero R, Scalea TM, Fabian TC. Evaluation and management of blunt traumatic aortic injury: a practice management guideline from the Eastern Association for the Surgery of Trauma. J Trauma Acute Care Surg. 2015 Jan;78(1):136-46. doi: 10.1097/TA.0000000000000470. Erratum in: J Trauma Acute Care Surg. 2015 Feb;78(2):447. PMID: 25539215 [PubMed - indexed for MEDLINE]

Saksobhavivat N, Shanmuganathan K, Chen HH, DuBose JJ, Richard H, Khan MA, Menaker J, Mirvis SE, Scalea TM. Blunt splenic injury: use of a multidetector CT-based splenic injury grading system and clinical parameters for triage of patients at admission. Radiology. 2015 Mar;274(3):702-11. doi: 10.1148/radiol.14141060. Epub 2014 Dec 3. PMID: 25474179 [PubMed - indexed for MEDLINE]

Kalpakis K, Yang S, Hu PF, Mackenzie CF, Stansbury LG, Stein DM, Scalea TM. Permutation entropy analysis of vital signs data for outcome prediction of patients with severe traumatic brain injury. Comput Biol Med. 2015 Jan;56:167-74. doi: 10.1016/j.compbiomed.2014.11.007. Epub 2014 Nov 15. PMID: 25464358 [PubMed - indexed for MEDLINE]

Tinubu J, Scalea TM. Management of fractures in a geriatric surgical patient. Surg Clin North Am. 2015 Feb;95(1):115-28. doi: 10.1016/j.suc.2014.09.017. Epub 2014 Nov 20. Review. PMID: 25459546 [PubMed - indexed for MEDLINE]

Harris DG, Rabin J, Kufera JA, Taylor BS, Sarkar R, O'Connor JV, Scalea TM, Crawford RS. A new aortic injury score predicts early rupture more accurately than clinical assessment. J Vasc Surg. 2015 Feb;61(2):332-8. doi: 10.1016/j.jvs.2014.08.007. Epub 2014 Sep 5. PMID: 25195146 [PubMed - indexed for MEDLINE]

Harris DG, McCrone MP, Koo G, Weltz AS, Chiu WC, Scalea TM, Diaz JJ, Lissauer ME. Epidemiology and outcomes of acute kidney injury in critically ill surgical patients. J Crit Care. 2015 Feb;30(1):102-6. doi: 10.1016/j.jcrc.2014.07.028. Epub 2014 Aug 6. PMID: 25171816 [PubMed - indexed for MEDLINE]

Seamon MJ, Haut ER, Van Arendonk K, Barbosa RR, Chiu WC, Dente CJ, Fox N, Jawa RS, Khwaja K, Lee JK, Magnotti LJ, Mayglothling JA, McDonald AA, Rowell S, To KB, Falck-Ytter Y, Rhee P. An evidence-based approach to patient selection for emergency department thoracotomy: A practice management guideline from the Eastern Association for the Surgery of Trauma. J Trauma Acute Care Surg. 2015 Jul;79(1):159-73. doi: 10.1097/TA.0000000000000648. PMID: 26091330 [PubMed - indexed for MEDLINE]

Diez C, Conti B, McCunn M, Aboutanos MB, Varon AJ. CASE 6—2015: Penetrating Biventricular Cardiac Injury in a Trauma Patient: Heart Versus Machete. J Cardiothorac Vasc Anesth. 2015;29(3):797-805. doi: 10.1053/j.jvca.2015.01.017. Epub 2015 Jan 8. No abstract available. PMID: 25863730 [PubMed - in process]

Sarani B, Schulte L, Diaz JJ. Pitfalls associated with open reduction and internal fixation of fractured ribs. Injury. 2015 Dec;46(12):2335-40. doi: 10.1016/j.injury.2015.10.022. Epub 2015 Oct 21. Review. PMID: 26521992 [PubMed - in process]

O'Meara L, Ahmad SB, Glaser J, Diaz JJ, Bruns BR. Outcomes of primary fascial closure after open abdomen for nontrauma emergency general surgery patients. Am J Surg. 2015 Dec;210(6):1126-31. doi: 10.1016/j.amjsurg.2015.06.030. Epub 2015 Sep 26. PMID: 26520871 [PubMed - in process]

Sartelli M, Abu-Zidan FM, Ansaloni L, Bala M, Beltrán MA, Biffl WL, Catena F, Chiara O, Coccolini F, Coimbra R, Demetrashvili Z, Demetriades D, Diaz JJ, Di Saverio S, Fraga GP, Ghnnam W, Griffiths EA, Gupta S, Hecker A, Karamarkovic A, Kong VY, Kafka-Ritsch R, Kluger Y, Latifi R, Leppaniemi A, Lee JG, McFarlane M, Marwah S, Moore FA, Ordonez CA, Pereira GA, Plaudis H, Shelat VG, Ulrych J, Zachariah SK, Zielinski MD, Garcia MP, Moore EE. The role of the open abdomen procedure in managing severe abdominal sepsis: WSES position paper. World J Emerg Surg. 2015 Aug 12;10:35. doi: 10.1186/s13017-015-0032-7. eCollection 2015. Review. PMID: 26269709 [PubMed]

Weltz AS, Harris DG, O'Neill NA, O'Meara LB, Brenner ML, Diaz JJ. The use of resuscitative endovascular balloon occlusion of the aorta to control hemorrhagic shock during video-assisted retroperitoneal debridement or infected necrotizing pancreatitis. Int J Surg Case Rep. 2015;13:15-8. doi: 10.1016/j.ijscr.2015.05.027. Epub 2015 May 30. PMID: 26074486 [PubMed]

Narayan M, Tesoriero R, Bruns BR, Klyushnenkova EN, Chen H, Diaz JJ. Acute care surgery: defining mortality in emergency general surgery in the state of Maryland. J Am Coll Surg. 2015 Apr;220(4):762-70. doi: 10.1016/j.jamcollsurg.2014.12.051. Epub 2015 Jan 22. PMID: 25797764 [PubMed - indexed for MEDLINE]

Marcel V, Catez F, Diaz JJ. p53, a translational regulator: contribution to its tumour-suppressor activity. Oncogene. 2015 Oct 29;34(44):5513-23. doi: 10.1038/onc.2015.25. Epub 2015 Mar 2. Review. PMID: 25728674 [PubMed - in process]

Couderc C, Bollard J, Couté Y, Massoma P, Poncet G, Lepinasse F, Hervieu V, Gadot N, Sanchez JC, Scoazec JY, Diaz JJ, Roche C.Mechanisms of local invasion in enteroendocrine tumors: identification of novel candidate cytoskeleton-associated proteins in an experimental mouse model by a proteomic approach and validation in human tumors. Mol Cell Endocrinol. 2015 Jan 5;399:154-63. doi: 10.1016/j.mce.2014.09.006. Epub 2014 Sep 16. PMID: 25224486 [PubMed - indexed for MEDLINE]

Fang R, Markandaya M, DuBose JJ, Cancio LC, Shackelford S, Blackbourne LH. Early in-theater management of combat-related traumatic brain injury: A prospective, observational study to identify opportunities for performance improvement. J Trauma Acute Care Surg. 2015 Oct;79(4 Suppl 2):S181-7. doi: 10.1097/TA.0000000000000769. PMID: 26406428 [PubMed - indexed for MEDLINE]

Bonds BW, Hu P, Li Y, Yang S, Colton K, Gonchigar A, Cheriyan J, Grissom T, Fang R, Stein DM. Predictive value of hyperthermia and intracranial hypertension on neurological outcomes in patients with severe traumatic brain injury. Brain Inj. 2015 Dec;29(13-14):1642-7. doi: 10.3109/02699052.2015.1075157. Epub 2015 Oct 19. PMID: 26479461 [PubMed - in process]

Stewart IJ, Sosnov JA, Howard JT, Orman JA, Fang R, Morrow BD, Zonies DH, Bollinger M, Tuman C, Freedman BA, Chung KK.Retrospective Analysis of Long-Term Outcomes After Combat Injury: A Hidden Cost of War. Circulation. 2015 Dec 1;132(22):2126-33. doi: 10.1161/CIRCULATIONAHA.115.016950. Epub 2015 Nov 2. PMID: 26621637 [PubMed - in process]

Stewart IJ, Faulk TI, Sosnov JA, Clemens MS, Elterman J, Ross JD, Howard JT, Fang R, Zonies DH, Chung KK. Rhabdomyolysis among critically ill combat casualties: associations with acute kidney injury and mortality. J Trauma Acute Care Surg. 2015 Dec 14. [Epub ahead of print] PMID: 26670111 [PubMed - as supplied by publisher]

Mackenzie CF, Gao C, Hu PF, Anazodo A, Chen H, Dinardo T, Imle PC, Hartsky L, Stephens C, Menaker J, Fouche Y, Murdock K, Galvagno S, Alcorta R, Shackelford S; ONPOINT Study Group. Comparison of Decision-Assist and Clinical Judgment of Experts for Prediction of Lifesaving Interventions. Shock. 2015 Mar;43(3):238-43. doi: 10.1097/SHK.0000000000000288. PMID: 25394243 [PubMed - in process]

Grissom TE, Fang R. Topical hemostatic agents and dressings in the prehospital setting. Curr Opin Anaesthesiol. 2015 Apr;28(2):210-6. doi: 10.1097/ACO.0000000000000166. Review. PMID: 25674988 [PubMed - indexed for MEDLINE]

Pasley J, Miller CH, DuBose JJ, Shackelford SA, Fang R, Boswell K, Halcome C, Casey J, Cotter M, Matsuura M, Relph N, Tarmey NT, Stein DM. Intraosseous infusion rates under high pressure: a cadaveric comparison of anatomic sites. J Trauma Acute Care Surg. 2015 Feb;78(2):295-9. doi: 10.1097/TA.0000000000000516. PMID: 25757113 [PubMed - indexed for MEDLINE]

Elterman J, Zonies D, Stewart I, Fang R, Schreiber M. Rhabdomyolysis and acute kidney injury in the injured war fighter. J Trauma Acute Care Surg. 2015 Oct;79(4 Suppl 2):S171-4. doi: 10.1097/TA.0000000000000572. PMID: 26131786 [PubMed - indexed for MEDLINE]

Shackelford S, Yang S, Hu P, Miller C, Anazodo A, Galvagno S, Wang Y, Hartsky L, Fang R, Mackenzie C; ONPOINT Study Group.Predicting blood transfusion using automated analysis of pulse oximetry signals and laboratory values. J Trauma Acute Care Surg. 2015 Oct;79(4 Suppl 2):S175-80. doi: 10.1097/TA.0000000000000738. PMID: 26406427 [PubMed - indexed for MEDLINE]

Proctor JL, Scutella D, Pan Y, Vaughan J, Rosenthal RE, Puche A, Fiskum G. Hyperoxic resuscitation improves survival but worsens neurologic outcome in a rat polytrauma model of traumatic brain injury plus hemorrhagic shock. J Trauma Acute Care Surg. 2015 Oct;79(4 Suppl 2):S101-9. doi: 10.1097/TA.0000000000000742. PMID: 26406421 [PubMed - indexed for MEDLINE]

Choe M, Brusgard JL, Chumsri S, Bhandary L, Zhao XF, Lu S, Goloubeva OG, Polster BM, Fiskum GM, Girnun GD, Kim MS, Passaniti A.The RUNX2 Transcription Factor Negatively Regulates SIRT6 Expression to Alter Glucose Metabolism in Breast Cancer Cells. J Cell Biochem. 2015 Oct;116(10):2210-26. doi: 10.1002/jcb.25171. PMID: 25808624 [PubMed - in process]

Kahraman S, Siegel A, Polster BM, Fiskum G. Permeability transition pore-dependent and PARP-mediated depletion of neuronal pyridine nucleotides during anoxia and glucose deprivation. J Bioenerg Biomembr. 2015 Apr;47(1-2):53-61. doi: 10.1007/s10863-014-9588-2. Epub 2014 Oct 24. PMID: 25341378 [PubMed - indexed for MEDLINE]

Galvagno SM Jr, Sikorski R, Hirshon JM, Floccare D, Stephens C, Beecher D, Thomas S. Helicopter emergency medical services for adults with major trauma. Cochrane Database Syst Rev. 2015 Dec 15;12:CD009228. doi: 10.1002/14651858.CD009228.pub3. Review. PMID: 26671262 [PubMed - in process]

Hirshon JM, Galvagno SM Jr, Comer A, Millin MG, Floccare DJ, Alcorta RL, Lawner BJ, Margolis AM, Nable JV, Bass RR. Maryland's Helicopter Emergency Medical Services Experience From 2001 to 2011: System Improvements and Patients' Outcomes. Ann Emerg Med. 2015 Sep 18. pii: S0196-0644(15)01093-8. doi: 10.1016/j.annemergmed.2015.07.503. [Epub ahead of print] PMID: 26433494 [PubMed - as supplied by publisher]

Shackelford SA, Fowler M, Schultz K, Summers A, Galvagno SM, Gross KR, Mabry RL, Bailey JA, Kotwal RS, Butler FK. Prehospital pain medication use by U.S. Forces in Afghanistan. Mil Med. 2015 Mar;180(3):304-9. doi: 10.7205/MILMED-D-14-00257. PMID: 25735021 [PubMed - in process]

Galvagno SM Jr, Hu P, Yang S, Gao C, Hanna D, Shackelford S, Mackenzie C. Accuracy of continuous noninvasive hemoglobin monitoring for the prediction of blood transfusions in trauma patients. J Clin Monit Comput. 2015 Dec;29(6):815-21. doi: 10.1007/s10877-015-9671-1. Epub 2015 Mar 10. PMID: 25753142 [PubMed - in process]

Novak DJ, Bai Y, Cooke RK, Marques MB, Fontaine MJ, Gottschall JL, Carey PM, Scanlan RM, Fiebig EW, Shulman IA, Nelson JM, Flax S, Duncan V, Daniel-Johnson JA, Callum JL, Holcomb JB, Fox EE, Baraniuk S, Tilley BC, Schreiber MA, Inaba K, Rizoli S, Podbielski JM, Cotton BA, Hess JR; PROPPR Study Group. Making thawed universal donor plasma available rapidly for massively bleeding trauma patients: experience from the Pragmatic, Randomized Optimal Platelets and Plasma Ratios (PROPPR) trial. Transfusion. 2015 Jun;55(6):1331-9. doi: 10.1111/trf.13098. Epub 2015 Mar 30. PMID: 25823522 [PubMed - indexed for MEDLINE]

Widener MJ, Ginsberg Z, Schleith D, Floccare DJ, Hirshon JM, Galvagno S. Ground and Helicopter Emergency Medical Services Time Tradeoffs Assessed with Geographic Information. Aerosp Med Hum Perform. 2015 Jul;86(7):620-7. doi: 10.3357/AMHP.4173.2015. PMID: 26102142 [PubMed - indexed for MEDLINE]

McCunn M, Dutton RP, Dagal A, Varon AJ, Kaslow O, Kucik CJ, Hagberg CA, McIsaac JH 3rd, Pittet JF, Dunbar PJ, Grissom T, Vavilala MS. Trauma, Critical Care, and Emergency Care Anesthesiology: A New Paradigm for the "Acute Care" Anesthesiologist?Anesth Analg. 2015 Dec;121(6):1668-73. doi: 10.1213/ANE.0000000000000782. No abstract available. PMID: 26579665 [PubMed - in process]

Kotloff RM, Blosser S, Fulda GJ, Malinoski D, Ahya VN, Angel L, Byrnes MC, DeVita MA, Grissom TE, Halpern SD, Nakagawa TA, Stock PG, Sudan DL, Wood KE, Anillo SJ, Bleck TP, Eidbo EE, Fowler RA, Glazier AK, Gries C, Hasz R, Herr D, Khan A, Landsberg D, Lebovitz DJ, Levine DJ, Mathur M, Naik P, Niemann CU, Nunley DR, O'Connor KJ, Pelletier SJ, Rahman O, Ranjan D, Salim A, Sawyer RG, Shafer T, Sonneti D, Spiro P, Valapour M, Vikraman-Sushama D, Whelan TP; Society of Critical Care Medicine/American College of Chest Physicians/Association of Organ Procurement Organizations Donor Management Task Force. Management of the Potential Organ Donor in the ICU: Society of Critical Care Medicine/American College of Chest Physicians/Association of Organ Procurement Organizations Consensus Statement. Crit Care Med. 2015 Jun;43(6):1291-325. doi: 10.1097/CCM.0000000000000958. PMID: 25978154 [PubMed - indexed for MEDLINE]

Lawner BJ, Hirshon JM, Comer AC, Nable JV, Kelly J, Alcorta RL, Pimentel L, Tupe CL, Vanhoy MA, Browne BJ. The impact of a freestanding ED on a regional emergency medical services system. Am J Emerg Med. 2015 Nov 18. pii: S0735-6757(15)01020-7. doi: 10.1016/j.ajem.2015.11.042. [Epub ahead of print] PMID: 26686934 [PubMed - as supplied by publisher]

Anderson D, Pimentel L, Golden B, Wasil E, Hirshon JM. Drivers of ED efficiency: a statistical and cluster analysis of volume, staffing, and operations. Am J Emerg Med. 2015 Oct 3. pii: S0735-6757(15)00817-7. doi: 10.1016/j.ajem.2015.09.034. [Epub ahead of print] PMID: 26508583 [PubMed - as supplied by publisher]

Albrecht JS, Hirshon JM, McCunn M, Bechtold KT, Rao V, Simoni-Wastila L, Smith GS. Increased Rates of Mild Traumatic Brain Injury Among Older Adults in US Emergency Departments, 2009-2010. J Head Trauma Rehabil. 2015 Oct 16. [Epub ahead of print] PMID: 26479396 [PubMed - as supplied by publisher]

Elboray S, Elawdy MY, Dewedar S, Elezz NA, El-Setouhy M, Smith GS, Hirshon JM. Knowledge, attitudes, and practices of family physicians and nurses regarding unintentional injuries among children under 15 years in Cairo, Egypt. Int J Inj Contr Saf Promot. 2015 Jul 15:1-8. [Epub ahead of print] PMID: 26176681 [PubMed - as supplied by publisher]

El-Shinawi M, McCunn M, Sisley AC, El-Setouhy M, Hirshon JM. Developing sustainable trauma care education in Egypt: sequential trauma education program, steps to success. J Surg Educ. 2015 Jul-Aug;72(4):e29-32. doi: 10.1016/j.jsurg.2014.12.001. Epub 2015 Jan 16. PMID: 25600355 [PubMed - in process]

Galey J, Bharadwaj S, Crimmins S, Hong CM, Malinow AM. Anesthetic Implications of an Obstetric Patient with Blue Rubber Bleb Nevus Syndrome. A A Case Rep. 2015 Nov 17. [Epub ahead of print] PMID: 26579613 [PubMed - as supplied by publisher]

Kim DH, Jung JH, Son SH, Kim CY, Hong CM, Oh JR, Jeong SY, Lee SW, Lee J, Ahn BC. Prognostic Significance of Intratumoral Metabolic Heterogeneity on 18F-FDG PET/CT in Pathological N0 Non-Small Cell Lung Cancer. Clin Nucl Med. 2015 Sep;40(9):708-14. doi: 10.1097/RLU.0000000000000867. PMID: 26098287 [PubMed - in process]

Sun X, Crawford R, Liu C, Luo T, Hu B. Development-dependent regulation of molecular chaperones after hypoxia-ischemia.Neurobiol Dis. 2015 Oct;82:123-31. doi: 10.1016/j.nbd.2015.06.001. Epub 2015 Jun 9. PMID: 26070787 [PubMed - in process]

Park Y, Liu C, Luo T, Dietrich WD, Bramlett H, Hu B. Chaperone-Mediated Autophagy after Traumatic Brain Injury. J Neurotrauma. 2015 Oct 1;32(19):1449-57. doi: 10.1089/neu.2014.3694. Epub 2015 Jun 30. PMID: 25891649 [PubMed - in process]

Luo T, Roman P, Liu C, Sun X, Park Y, Hu B. Upregulation of the GEF-H1 pathway after transient cerebral ischemia. Exp Neurol. 2015 Jan;263:306-13. doi: 10.1016/j.expneurol.2014.10.016. Epub 2014 Oct 29. PMID: 25447939 [PubMed - indexed for MEDLINE]  

Rock C, Thom KA, Harris AD, Li S, Morgan D, Milstone AL, Caffo B, Joshi M, Leekha S. A Multicenter Longitudinal Study of Hospital-Onset Bacteremia: Time for a New Quality Outcome Measure? Infect Control Hosp Epidemiol. 2015 Oct 23:1-6. [Epub ahead of print] PMID: 26493213 [PubMed - as supplied by publisher]

Vranis N, Paryavi E, Christian M, Joshi M, Pensy RA. Septic Arthritis and Osteomyelitis Caused by Pasteurella multocida. Am J Orthop (Belle Mead NJ). 2015 Jul;44(7):E239-41. PMID: 26161771 [PubMed - in process]

Torbert JT, Joshi M, Moraff A, Matuszewski PE, Holmes A, Pollak AN, OʼToole RV. Current bacterial speciation and antibiotic resistance in deep infections after operative fixation of fractures. J Orthop Trauma. 2015 Jan;29(1):7-17. doi: 10.1097/BOT.0000000000000158. PMID: 24854665 [PubMed - indexed for MEDLINE]

Long AN, Owens K, Schlappal AE, Kristian T, Fishman PS, Schuh RA. Effect of nicotinamide mononucleotide on brain mitochondrial respiratory deficits in an Alzheimer's disease-relevant murine model. BMC Neurol. 2015 Mar 1;15:19. doi: 10.1186/s12883-015-0272-x. PMID: 25884176 [PubMed - in process]  

Owens K, Park JH, Gourley S, Jones H, Kristian T. Mitochondrial dynamics: cell-type and hippocampal region specific changes following global cerebral ischemia. J Bioenerg Biomembr. 2015 Apr;47(1-2):13-31. doi: 10.1007/s10863-014-9575-7. Epub 2014 Sep 24. PMID: 25248415 [PubMed - indexed for MEDLINE]

Awad O, Sarkar C, Panicker LM, Miller D, Zeng X, Sgambato JA, Lipinski MM, Feldman RA. Altered TFEB-mediated lysosomal biogenesis in Gaucher disease iPSC-derived neuronal cells. Hum Mol Genet. 2015 Oct 15;24(20):5775-88. doi: 10.1093/hmg/ddv297. Epub 2015 Jul 28. PMID: 26220978 [PubMed - in process]

Lipinski MM, Wu J. Modification of autophagy-lysosomal pathway as a neuroprotective treatment for spinal cord injury. Neural Regen Res. 2015 Jun;10(6):892-3. doi: 10.4103/1673-5374.158344. No abstract available. PMID: 26199601 [PubMed]  

Zhang T, Dong K, Liang W, Xu D, Xia H, Geng J, Najafov A, Liu M, Li Y, Han X, Xiao J, Jin Z, Peng T, Gao Y, Cai Y, Qi C, Zhang Q, Sun A, Lipinski M, Zhu H, Xiong Y, Pandolfi PP, Li H, Yu Q, Yuan J. G-protein-coupled receptors regulate autophagy by ZBTB16-mediated ubiquitination and proteasomal degradation of Atg14L. Elife. 2015 Mar 30;4:e06734. doi: 10.7554/eLife.06734. PMID: 25821988 [PubMed - in process]

Loane DJ, Kumar A. Microglia in the TBI brain: The good, the bad, and the dysregulated. Exp Neurol. 2016 Jan;275 Pt 3:316-27. doi: 10.1016/j.expneurol.2015.08.018. Epub 2015 Sep 3. Review. PMID: 26342753 [PubMed - in process]

Mackenzie CF, Garofalo E, Shackelford S, Shalin V, Pugh K, Chen H, Puche A, Pasley J, Sarani B, Henry S, Bowyer M. Using an Individual Procedure Score Before and After the Advanced Surgical Skills Exposure for Trauma Course Training to Benchmark a Hemorrhage-Control Performance Metric. J Surg Educ. 2015 Nov-Dec;72(6):1278-89. doi: 10.1016/j.jsurg.2015.06.009. Epub 2015 Jul 23. PMID: 26211969 [PubMed - in process]

Mackenzie C, Klee G. Guide to Selecting the Right Ear Muff. Occup Health Saf. 2015 Jun;84(6):20, 22, 24. No abstract available. PMID: 26155686 [PubMed - indexed for MEDLINE]

Shackelford S, Garofalo E, Shalin V, Pugh K, Chen H, Pasley J, Sarani B, Henry S, Bowyer M, Mackenzie CF. Development and validation of trauma surgical skills metrics: Preliminary assessment of performance after training. J Trauma Acute Care Surg. 2015 Jul;79(1):105-10. doi: 10.1097/TA.0000000000000685. PMID: 26091322 [PubMed - indexed for MEDLINE]

Simon MC, Strassburger K, Nowotny B, Kolb H, Nowotny P, Burkart V, Zivehe F, Hwang JH, Stehle P, Pacini G, Hartmann B, Holst JJ, MacKenzie C, Bindels LB, Martinez I, Walter J, Henrich B, Schloot NC, Roden M. Intake of Lactobacillus reuteri improves incretin and insulin secretion in glucose-tolerant humans: a proof of concept. Diabetes Care. 2015 Oct;38(10):1827-34. doi: 10.2337/dc14-2690. Epub 2015 Jun 17. PMID: 26084343 [PubMed - in process]

Bowyer MW, Shackelford SA, Garofalo E, Pugh K, Mackenzie CF. Perception does not equal reality for resident vascular trauma skills. J Surg Res. 2015 Oct;198(2):280-8. doi: 10.1016/j.jss.2015.03.082. Epub 2015 Apr 1. PMID: 25918003 [PubMed - indexed for MEDLINE]

Wendel AF, Kolbe-Busch S, Ressina S, Schulze-Röbbecke R, Kindgen-Milles D, Lorenz C, Pfeffer K, MacKenzie CR. Detection and termination of an extended low-frequency hospital outbreak of GIM-1-producing Pseudomonas aeruginosa ST111 in Germany.Am J Infect Control. 2015 Jun;43(6):635-9. doi: 10.1016/j.ajic.2015.02.024. Epub 2015 Apr 11. PMID: 25868648 [PubMed - in process]

Steindor M, Nkwouano V, Mayatepek E, Mackenzie CR, Schramm D, Jacobsen M. Rapid detection and immune characterization of Mycobacterium abscessus infection in cystic fibrosis patients. PLoS One. 2015 Mar 5;10(3):e0119737. doi: 10.1371/journal.pone.0119737. eCollection 2015. PMID: 25742660 [PubMed - in process]  

Njoku M, St Peter D, Mackenzie CF. Haemoglobin-based oxygen carriers: indications and future applications. Br J Hosp Med (Lond). 2015 Feb;76(2):78-83. doi: 10.12968/hmed.2015.76.2.78. Review. PMID: 25671471 [PubMed - indexed for MEDLINE]

Wendel AF, MacKenzie CR. Characterization of a novel metallo-β-lactamase variant, GIM-2, from a clinical isolate of Enterobacter cloacae in Germany. Antimicrob Agents Chemother. 2015 Mar;59(3):1824-5. doi: 10.1128/AAC.05062-14. Epub 2014 Dec 29. No abstract available. PMID: 25547359 [PubMed - indexed for MEDLINE]  

Anazodo AN, Murthi SB, Frank MK, Hu PF, Hartsky L, Imle PC, Stephens CT, Menaker J, Miller C, Dinardo T, Pasley J, Mackenzie CF.Assessing trauma care provider judgement in the prediction of need for life-saving interventions. Injury. 2015 May;46(5):791-7. doi: 10.1016/j.injury.2014.10.063. Epub 2014 Nov 18. PMID: 25541418 [PubMed - in process]

Mackenzie CF, Pitman AN, Hodgson RE, Sussman MJ, Levien LJ, Jahr JS, Greenburg AG. Are Hemoglobin-Based Oxygen Carriers Being Withheld Because of Regulatory Requirement for Equivalence to Packed Red Blood Cells? Am J Ther. 2015 Jul-Aug;22(4):e115-21. doi: 10.1097/MJT.0000000000000009. No abstract available. PMID: 25285795 [PubMed - indexed for MEDLINE]

Mazzeffi M, Greenwood J, Tanaka K, Menaker J, Rector R, Herr D, Kon Z, Lee J, Griffith B, Rajagopal K, Pham S. Bleeding, Transfusion, and Mortality on Extracorporeal Life Support: ECLS Working Groupon Thrombosis and Hemostasis. Ann Thorac Surg. 2015 Oct 3. pii: S0003-4975(15)01250-3. doi: 10.1016/j.athoracsur.2015.07.046. [Epub ahead of print] PMID: 26443879 [PubMed - as supplied by publisher]

Qasim Z, Brenner M, Menaker J, Scalea T. Resuscitative endovascular balloon occlusion of the aorta. Resuscitation. 2015 Nov;96:275-9. doi: 10.1016/j.resuscitation.2015.09.003. Epub 2015 Sep 16. Review. PMID: 26386370 [PubMed - in process]

Mazzeffi M, Kiefer J, Greenwood J, Tanaka K, Menaker J, Kon Z, Sanchez P, Pham S, Herr D. Epidemiology of gastrointestinal bleeding in adult patients on extracorporeal life support. Intensive Care Med. 2015 Nov;41(11):2015. doi: 10.1007/s00134-015-4006-8. Epub 2015 Aug 12. No abstract available. PMID: 26264245 [PubMed - in process]

Wisner DH, Kuppermann N, Cooper A, Menaker J, Ehrlich P, Kooistra J, Mahajan P, Lee L, Cook LJ, Yen K, Lillis K, Holmes JF.Management of children with solid organ injuries after blunt torso trauma. J Trauma Acute Care Surg. 2015 Aug;79(2):206-14;quiz 332. doi: 10.1097/TA.0000000000000731. PMID: 26218687 [PubMed - indexed for MEDLINE]

DuBose JJ, Savage SA, Fabian TC, Menaker J, Scalea T, Holcomb JB, Skarupa D, Poulin N, Chourliaras K, Inaba K, Rasmussen TE; AAST PROOVIT Study Group. The American Association for the Surgery of Trauma PROspective Observational Vascular Injury Treatment (PROOVIT) registry: multicenter data on modern vascular injury diagnosis, management, and outcomes. J Trauma Acute Care Surg. 2015 Feb;78(2):215-22; discussion 222-3. doi: 10.1097/TA.0000000000000520. Erratum in: J Trauma Acute Care Surg. 2015 Mar;78(3):657. PMID: 25757104 [PubMed - indexed for MEDLINE]

Inaba K, Nosanov L, Menaker J, Bosarge P, Williams L, Turay D, Cachecho R, de Moya M, Bukur M, Carl J, Kobayashi L, Kaminski S, Beekley A, Gomez M, Skiada D; AAST TL-Spine Multicenter Study Group. Prospective derivation of a clinical decision rule for thoracolumbar spine evaluation after blunt trauma: An American Association for the Surgery of Trauma Multi-Institutional Trials Group Study. J Trauma Acute Care Surg. 2015 Mar;78(3):459-65; discussion 465-7. doi: 10.1097/TA.0000000000000560. PMID: 25710414 [PubMed - indexed for MEDLINE]

Xu S, Cherok E, Das S, Li S, Roelofs BA, Ge SX, Polster BM, Boyman L, Lederer WJ, Wang C, Karbowski M. Mitochondrial E3 ubiquitin ligase MARCH5 controls mitochondrial fission and cell sensitivity to stress-induced apoptosis through regulation of MiD49 protein. Mol Biol Cell. 2015 Nov 12. pii: mbc.E15-09-0678. [Epub ahead of print] PMID: 26564796 [PubMed - as supplied by publisher]

Nichols M, Zhang J, Polster BM, Elustondo PA, Thirumaran A, Pavlov EV, Robertson GS. Synergistic neuroprotection by epicatechin and quercetin: Activation of convergent mitochondrial signaling pathways. Neuroscience. 2015 Nov 12;308:75-94. doi: 10.1016/j.neuroscience.2015.09.012. Epub 2015 Sep 10. PMID: 26363153 [PubMed - in process]

Roelofs BA, Ge SX, Studlack PE, Polster BM. Low micromolar concentrations of the superoxide probe MitoSOX uncouple neural mitochondria and inhibit complex IV. Free Radic Biol Med. 2015 Sep;86:250-8. doi: 10.1016/j.freeradbiomed.2015.05.032. Epub 2015 Jun 6. PMID: 26057935 [PubMed - in process]

Bol GM, Vesuna F, Xie M, Zeng J, Aziz K, Gandhi N, Levine A, Irving A, Korz D, Tantravedi S, Heerma van Voss MR, Gabrielson K, Bordt EA, Polster BM, Cope L, van der Groep P, Kondaskar A, Rudek MA, Hosmane RS, van der Wall E, van Diest PJ, Tran PT, Raman V.Targeting DDX3 with a small molecule inhibitor for lung cancer therapy. EMBO Mol Med. 2015 Mar 27;7(5):648-69. doi: 10.15252/emmm.201404368. PMID: 25820276 [PubMed - in process]  

Jaber S, Polster BM. Idebenone and neuroprotection: antioxidant, pro-oxidant, or electron carrier? J Bioenerg Biomembr. 2015 Apr;47(1-2):111-8. doi: 10.1007/s10863-014-9571-y. Epub 2014 Sep 28. Review. PMID: 25262284 [PubMed - indexed for MEDLINE]

Chan RC, Xie W, Geng FL, Wang Y, Lui SS, Wang CY, Yu X, Cheung EF, Rosenthal R. Clinical Utility and Lifespan Profiling of Neurological Soft Signs in Schizophrenia Spectrum Disorders. Schizophr Bull. 2015 Dec 28. pii: sbv196. [Epub ahead of print] PMID: 26712863 [PubMed - as supplied by publisher]

Rosenthal R. Reflections on the origins of meta-analysis. Res Synth Methods. 2015 Sep;6(3):240-5. doi: 10.1002/jrsm.1135. Epub 2015 Feb 12. PMID: 26355797 [PubMed - in process]

Rosenthal RL. The 50% coronary stenosis. Am J Cardiol. 2015 Apr 15;115(8):1162-5. doi: 10.1016/j.amjcard.2015.01.553. Epub 2015 Feb 3. No abstract available. PMID: 25726382 [PubMed - indexed for MEDLINE]

Hwang DY, Dell CA, Sparks MJ, Watson TD, Langefeld CD, Comeau ME, Rosand J, Battey TW, Koch S, Perez ML, James ML, McFarlin J, Osborne JL, Woo D, Kittner SJ, Sheth KN. Clinician judgment vs formal scales for predicting intracerebral hemorrhage outcomes.Neurology. 2015 Dec 16. pii: 10.1212/WNL.0000000000002266. [Epub ahead of print] PMID: 26674335 [PubMed - as supplied by publisher]

Asuzu D, Nystrӧm K, Amin H, Schindler J, Wira C, Greer D, Chi NF, Halliday J, Sheth KN. On- versus Off-Hour Patient Cohorts at a Primary Stroke Center: Onset-to-Treatment Duration and Clinical Outcomes after IV Thrombolysis. J Stroke Cerebrovasc Dis. 2015 Nov 30. pii: S1052-3057(15)00569-8. doi: 10.1016/j.jstrokecerebrovasdis.2015.10.017. [Epub ahead of print] PMID: 26654664 [PubMed - as supplied by publisher]

Sheth KN, Martini SR, Moomaw CJ, Koch S, Elkind MS, Sung G, Kittner SJ, Frankel M, Rosand J, Langefeld CD, Comeau ME, Waddy SP, Osborne J, Woo D; ERICH Investigators. Prophylactic Antiepileptic Drug Use and Outcome in the Ethnic/Racial Variations of Intracerebral Hemorrhage Study. Stroke. 2015 Dec;46(12):3532-5. doi: 10.1161/STROKEAHA.115.010875. Epub 2015 Oct 15. PMID: 26470777 [PubMed - in process]

Sheth KN. Management of Hemispheric Infarction and Ischemic Swelling. Continuum (Minneap Minn). 2015 Oct;21(5 Neurocritical Care):1346-61. doi: 10.1212/CON.0000000000000219. PMID: 26426234 [PubMed - in process]

Asuzu D, Nyström K, Sreekrishnan A, Schindler J, Wira C, Greer D, Halliday J, Kimberly WT, Sheth KN. TURN Score Predicts 24-Hour Cerebral Edema After IV Thrombolysis. Neurocrit Care. 2015 Sep 4. [Epub ahead of print] PMID: 26341364 [PubMed - as supplied by publisher]

Simard JM, Sheth KN. Is Glibenclamide the New Cool in Cardiopulmonary Resuscitation? Crit Care Med. 2015 Sep;43(9):2040-1. doi: 10.1097/CCM.0000000000001112. No abstract available. PMID: 26274718 [PubMed - indexed for MEDLINE]

Sheth KN, Elm JJ, Beslow LA, Sze GK, Kimberly WT. Glyburide Advantage in Malignant Edema and Stroke (GAMES-RP) Trial: Rationale and Design. Neurocrit Care. 2015 Aug 13. [Epub ahead of print] PMID: 26268138 [PubMed - as supplied by publisher]

Morris NA, Merkler AE, Parker WE, Claassen J, Connolly ES, Sheth KN, Kamel H. Adverse Outcomes After Initial Non-surgical Management of Subdural Hematoma: A Population-Based Study. Neurocrit Care. 2015 Jul 10. [Epub ahead of print] PMID: 26160466 [PubMed - as supplied by publisher]

Walsh KB, Sekar P, Langefeld CD, Moomaw CJ, Elkind MS, Boehme AK, James ML, Osborne J, Sheth KN, Woo D, Adeoye O. Monocyte Count and 30-Day Case Fatality in Intracerebral Hemorrhage. Stroke. 2015 Aug;46(8):2302-4. doi: 10.1161/STROKEAHA.115.009880. Epub 2015 Jun 30. PMID: 26130090 [PubMed - indexed for MEDLINE]

Asuzu D, Nyström K, Schindler J, Wira C, Greer D, Halliday J, Sheth KN. TURN Score Predicts 90-day Outcome in Acute Ischemic Stroke Patients After IV Thrombolysis. Neurocrit Care. 2015 Oct;23(2):172-8. doi: 10.1007/s12028-015-0154-5. PMID: 26032809 [PubMed - in process]

Maciel CB, Sheth KN. Malignant MCA Stroke: an Update on Surgical Decompression and Future Directions. Curr Atheroscler Rep. 2015 Jul;17(7):40. doi: 10.1007/s11883-015-0519-4. PMID: 26017393 [PubMed - in process]

Yeung JT, Matouk CC, Bulsara KR, Sheth KN. Endovascular revascularization for basilar artery occlusion. Interv Neurol. 2015 Jan;3(1):31-40. doi: 10.1159/000368968. Review. PMID: 25999990 [PubMed]  

Cai X, Robinson J, Muehlschlegel S, White DB, Holloway RG, Sheth KN, Fraenkel L, Hwang DY. Patient Preferences and Surrogate Decision Making in Neuroscience Intensive Care Units. Neurocrit Care. 2015 Aug;23(1):131-41. doi: 10.1007/s12028-015-0149-2. PMID: 25990137 [PubMed - in process]

Asuzu D, Nyström K, Amin H, Schindler J, Wira C, Greer D, Chi NF, Halliday J, Sheth KN. TURN: A Simple Predictor of Symptomatic Intracerebral Hemorrhage After IV Thrombolysis. Neurocrit Care. 2015 Oct;23(2):166-71. doi: 10.1007/s12028-015-0131-z. PMID: 25869481 [PubMed - in process]

Fountain NB, Van Ness PC, Bennett A, Absher J, Patel AD, Sheth KN, Gloss DS, Morita DA, Stecker M. Quality improvement in neurology: Epilepsy Update Quality Measurement Set. Neurology. 2015 Apr 7;84(14):1483-7. doi: 10.1212/WNL.0000000000001448. No abstract available. PMID: 25846995 [PubMed - indexed for MEDLINE]

Wilson JL, Poulin PA, Sikorski R, Nathan HJ, Taljaard M, Smyth C. Opioid use among same-day surgery patients: Prevalence, management and outcomes. Pain Res Manag. 2015 Nov-Dec;20(6):300-4. Epub 2015 Sep 10. PMID: 26357683 [PubMed - in process]  

Cap AP, Pidcoke HF, DePasquale M, Rappold JF, Glassberg E, Eliassen HS, Bjerkvig CK, Fosse TK, Kane S, Thompson P, Sikorski R, Miles E, Fisher A, Ward KR, Spinella PC, Strandenes G. Blood far forward: Time to get moving! J Trauma Acute Care Surg. 2015 Jun;78(6 Suppl 1):S2-6. doi: 10.1097/TA.0000000000000626. PMID: 26002259 [PubMed - indexed for MEDLINE]

Simmons J, Sikorski RA, Pittet JF. Tranexamic acid: from trauma to routine perioperative use. Curr Opin Anaesthesiol. 2015 Apr;28(2):191-200. doi: 10.1097/ACO.0000000000000165. Review. PMID: 25635366 [PubMed - indexed for MEDLINE]

Burns TM, Smith GA, Allen JA, Amato AA, Arnold WD, Barohn R, Benatar M, Bird SJ, Bromberg M, Chahin N, Ciafaloni E, Cohen JA, Corse A, Crum BA, David WS, Dimberg E, De Sousa EA, Donofrio PD, Dyck PJ, Engel AG, Ensrud ER, Ferrante M, Freimer M, Gable KL, Gibson S, Gilchrist JM, Goldstein JM, Gooch CL, Goodman BP, Gorelov D, Gospe SM Jr, Goyal NA, Guidon AC, Guptill JT, Gutmann L, Gutmann L, Gwathmey K, Harati Y, Harper CM Jr, Hehir MK, Hobson-Webb LD, Howard JF Jr, Jackson CE, Johnson N, Jones SM, Juel VC, Kaminski HJ, Karam C, Kennelly KD, Khella S, Khoury J, Kincaid JC, Kissel JT, Kolb N, Lacomis D, Ladha S, Larriviere D, Lewis RA, Li Y, Litchy WJ, Logigian E, Lou JS, MacGowen DJ, Maselli R, Massey JM, Mauermann ML, Mathews KD, Meriggioli MN, Miller RG, Moon JS, Mozaffar T, Nations SP, Nowak RJ, Ostrow LW, Pascuzzi RM, Peltier A, Ruzhansky K, Richman DP, Ross MA, Rubin DI, Russell JA, Sachs GM, Salajegheh MK, Saperstein DS, Scelsa S, Selcen D, Shaibani A, Sheih PB, Silvestri NJ, Singleton JR, Smith BE, So YT, Solorzano G, Sorenson EJ, Srinivasen J, Tavee J, Tawil R, Thaisetthawatkul P, Thornton C, Trivedi J, Vernino S, Wang AK, Webb TA, Weiss MD, Windebank AJ, Wolfe GI. Editorial by concerned physicians: Unintended effect of the Orphan Drug Act on the potential cost of 3,4-diaminopyridine. Muscle Nerve. 2015 Dec 10. doi: 10.1002/mus.25009. [Epub ahead of print] No abstract available. PMID: 26662952 [PubMed - as supplied by publisher]

Harvin JA, Taub EA, Cotton BA, Brocker J, Stein DM, Dilektasli E, Inaba K, Vella MA, Guillamondegui O, Kodadek LM, Haut ER, Evans CR, Weinberg JA, Goodman MD, Robinson BR, Holcomb JB. Airway management following repair of cervical tracheal injuries: A retrospective, multicenter study. J Trauma Acute Care Surg. 2015 Dec 14. [Epub ahead of print] PMID: 26670110 [PubMed - as supplied by publisher]

Stein DM, Pineda JA, Roddy V, Knight WA 4th. Emergency Neurological Life Support: Traumatic Spine Injury. Neurocrit Care. 2015 Dec;23 Suppl 2:155-64. doi: 10.1007/s12028-015-0169-y. PMID: 26438460 [PubMed - in process]

Dreizin D, Kim W, Kim JS, Boscak AR, Bodanapally UK, Munera F, Stein DM. Will the Real SCIWORA Please Stand Up? Exploring Clinicoradiologic Mismatch in Closed Spinal Cord Injuries. AJR Am J Roentgenol. 2015 Oct;205(4):853-60. doi: 10.2214/AJR.14.13374. PMID: 26397336 [PubMed - indexed for MEDLINE]

Bonds BW, Dhanda A, Wade C, Massetti J, Diaz C, Stein DM. Prognostication of Mortality and Long term Functional Outcomes Following Traumatic Brain Injury: Can We Do Better? J Neurotrauma. 2015 Jul 31. [Epub ahead of print] PMID: 26230149 [PubMed - as supplied by publisher]

Kozar RA, Arbabi S, Stein DM, Shackford SR, Barraco RD, Biffl WL, Brasel KJ, Cooper Z, Fakhry SM, Livingston D, Moore F, Luchette F.Injury in the aged: Geriatric trauma care at the crossroads. J Trauma Acute Care Surg. 2015 Jun;78(6):1197-209. doi: 10.1097/TA.0000000000000656. Review. No abstract available. PMID: 26151523 [PubMed - indexed for MEDLINE]

Laser A, Kufera JA, Bruns BR, Sliker CW, Tesoriero RB, Scalea TM, Stein DM. Initial screening test for blunt cerebrovascular injury: Validity assessment of whole-body computed tomography. Surgery. 2015 Sep;158(3):627-35. doi: 10.1016/j.surg.2015.03.063. Epub 2015 Jun 9. PMID: 26067461 [PubMed - indexed for MEDLINE]

Stein DM, Sheth KN. Management of acute spinal cord injury. Continuum (Minneap Minn). 2015 Feb;21(1 Spinal Cord Disorders):159-87. doi: 10.1212/01.CON.0000461091.09736.0c. Review. PMID: 25651224 [PubMed - indexed for MEDLINE]

Lin J, Marcolli M, Ooguri H, Stoica B. Locality of Gravitational Systems from Entanglement of Conformal Field Theories. Phys Rev Lett. 2015 Jun 5;114(22):221601. Epub 2015 Jun 2. PMID: 26196612 [PubMed]

Zhang F, Ren T, Wu J. TGF-β1 induces apoptosis of bone marrow-derived mesenchymal stem cells via regulation of mitochondrial reactive oxygen species production. Exp Ther Med. 2015 Sep;10(3):1224-1228. Epub 2015 Jun 23. PMID: 26622469 [PubMed]  

Zhang F, Ren T, Wu J, Niu J. Small concentrations of TGF-β1 promote proliferation of bone marrow-derived mesenchymal stem cells via activation of Wnt/β-catenin pathway. Indian J Exp Biol. 2015 Aug;53(8):508-13. PMID: 26349313 [PubMed - indexed for MEDLINE]

Niu J, Wu J, Li X, Zhang F. Association between endothelin-1/endothelin receptor A and inflammation in mouse kidneys following acute ischemia/reperfusion. Mol Med Rep. 2015 May;11(5):3981-7. doi: 10.3892/mmr.2014.3138. Epub 2014 Dec 30. PMID: 25572710 [PubMed - in process]


Loane, D. J., Stoica, B. A., Tchantchou, F., Kumar, A., Barrett, J. P., Akintola, T., & Faden, A. I. (2014). Novel mGluR5 Positive Allosteric Modulator Improves Functional Recovery, Attenuates Neurodegeneration, and Alters Microglial Polarization after Experimental Traumatic Brain Injury.  Neurotherapeutics, 1-13.

Kabadi SV, Faden AI. (2014). Selective CDK inhibitors: promising candidates for future clinical TBI trials. Neural Regeneration Research[accepted].

Skopin, M. D., Kabadi, S. V., Viechweg, S. S., Mong, J. A., Faden, A. I. (2014). Chronic decrease in wakefulness and disruption of sleep-wake behavior after experimental traumatic brain injury. Journal of Neurotrauma [accepted].

Lipinski, M. M., Liu, S., Sarkar, C., Dinizo, M., Faden, A. I., Koh, E., & Wu, J. (2014). Disrupted Autophagy after Spinal Cord Injury Is Associated with ER Stress and Neuronal Cell Death.  Cell Death and Disease [accepted].

Afshar M, Smith GS, Terrin ML, Barret M, Lissauer ME, Mansoor S, Jeudy J, Netzer G. "Blood Alcohol Content, Injury Severity and Acute Respiratory Distress Syndrome" J of Trauma 2014 accepted

Albrecht JS, Gruber-Baldini AL, Hirshon JM, Brown CH, Goldberg R, Rosenberg JH, Comer AC, Furuno JP. Depressive Symptoms and Hospital Readmission in Older Adults. J Am Geriatr Soc. 2014 Mar;62(3):495-9

Aungst, S., Kabadi, S.V., Thompson, S., Stoica, B., and Faden, AI. Repeated Mild Traumatic Brain Injury Causes Chronic Neuroinflammation, Changes in Hippocampal Synaptic Plasticity, and Associated Cognitive Deficits. Journal of Cerebral Blood Flow & Metabolism 2014 April [Epub ahead of print]

Burch C, Cook L, Dischinger, P.  A comparison of KABCO and AIS severity metrics using CODES linked data.  Traf Inj Prev. 2014; 15:1-4.

Clerc, P. Ge, S.X., Hwang, H., Waddell, J., Roelofs, B.A., Karbowski, M., Sesaki, H., and Polster, B.M.  (2014) Drp1 is dispensable for apoptotic cytochrome c release in primed MCF10A and fibroblast cells but affects Bcl-2 antagonist-induced respiratory changes.  Br J Pharmacol 171:1988-1999 (Invited contribution to a special issue entitled “Mitochondrial Pharmacology - Energy, Injury & Beyond”)

Colton, K., S Yang, PF Hu, HH Chen, B Bonds,  TM Scalea,  DM Stein. Intracranial pressure response after pharmacologic treatment of intracranial hypertension. J. Trauma Acute Care Surg (Accepted Feb,7, 2014)

Furuno JP, Comer AC, Johnson JK, Rosenberg JH, Moore SL, MacKenzie TD, Hall KK, Hirshon JM. Using Antibiograms to Improve Antibiotic Prescribing in Skilled Nursing Facilities. Infect Control Hosp Epidemiol. (in press)

Grissom T, Sappenfield J, Galvagno S, Cherry S, Chang C, Hu P. Performance Assessment in Airway Management Training for Nonanesthesiology Trainees: An Analysis of 4,282 Airway Procedures Performed at a Level 1 Trauma Center. J of Anesthesiology. 2014 Jan;120(1):185-95. PMID: 24201030

Galvagno SM, Dubose JJ, Grissom TE, Fang R, Smith R, Bebarta VS, Shackelford S, Scalea TM. The epidemiology of critical care air transport teams in contemporary warfare.  Military Medicine, 2014; Accepted for publication on 3 January 2014.

Hirshon JM, Alson RL, Blunk D, Brosnan DP, Epstein SK, Gardner AF, Lum DL, Moskovitz JB, Richardson LD, Stankus JL, Kivela PD, Wilkerson D, Price C, Bromley M, Calaway N, Geist M, Gore L, Singh C, Wheeler G. America's Emergency Care Environment, A State-by-State Report Card: 2014 Edition. Ann Emerg Med. 2014 Feb;63(2):100-243.

Hu P, Galvagno SM, Sen A, Dutton RP, Handley C, Shackelford S, Pasley JD, Mackenzie CF, and the ONPOINT Study Group. Identification of dynamic prehospital changes with continuous vital signs acquisition. Air Med J 2014; 33(1): 27-33.

Han K, MacDonald CL, Johnson AM, Barnes Y, Wierzechowski L, Zonies D, Oh J, Flaherty S, Fang R, Raichle ME, Brody DL. Disrupted modular organization of resting-state cortical functional connectivity in U.S. military personnel following concussive 'mild' blast-related traumatic brain injury. Neuroimage. 2014 Jan;84(1):76-96.

Kabadi SV, Stoica BA, Loane DJ, Luo T, Faden AI. Cell cycle inhibition limits microglial activation, astrocytosis, neuronal loss and neurological dysfunction after experimental traumatic brain injury. Journal of Cerebral Blood Flow and Metabolism. (in press).

Kabadi, S.V., Faden, A.I.  Review: Neuroprotective Strategies for Traumatic Brain Injury: Improving Clinical Translation.  International Journal of Molecular Sciences. (in press).

Knudson MM, Evans TW, Fang R, Martin KD, Dorlac WC, Gillespie DL, Cherry KJ, Rasmussen TE; American Association for the Surgery of Trauma, Military Liaison Committee; Society for Vascular Surgery; American College of Surgeon, Committee on Trauma. A concluding after-action report of the Senior Visiting Surgeon Program with the United States Military at Landstuhl Regional Medical Center, Germany. J Trauma Acute Care Surg. 2014 Mar;76(3):878-83.

Loane DJ, Kumar A, Stoica BA, Cabatbat R, Faden AI. Progressive neurodegeneration after experimental brain trauma; association with chronic microglial activation. Journal of Neuropathology and Experimental Neurology. (in press).

Liu, S., Sarkar, C., Koh, E.Y., Lipinski, M.M.* and Wu, J. Disrupted autophagy after spinal cord injury is associated with lysosomal dysfunction and neuronal cell death. – in preparation

Lissauer ME, Galvagno SM, Rock P, Narayan M, Shah P, Spencer H, Hong C, Diaz JJ. Increased intensive care unit resource needs for an academic emergency general surgery service.  Crit Care Med. Dec 11 2013 [Epub ahead of print].

MacDonald CL, Johnson AM, Wierzechowski L, Kassner E, Stewart T, Nelson EC, Werner NJ, Zonies D, Oh JS, Fang R, Brody DL. Prospectively assessed clinical outcomes in concussive blast vs. non-blast traumatic brain injury in evacuated US military personnel. JAMA Neurol. Forthcoming 2014.

MacDonald CL, Johnson AM, Nelson EC, Werner NJ, Fang R, Flaherty SF, Brody DL. Functional status following blast-plus-impact complex concussive traumatic brain injury in evacuated United States military personnel. J Neurotrauma. Forthcoming 2014.

Mackenzie, C., Wang, Y., Hu, PF, Chen, SY., Hagegeorge, G., Stansbury, LY, Shackelford, S. ONPOINT Study Group Automated prediction of early blood transfusion in trauma patients.  J Trauma Acute Care Surg  JT-D-13-02260R1  (Accepted Jan, 17, 2014)

Pajoohesh-Ganji A., Burns MPPal-Ghosh STadvalkar GHokenbury NGAnn Stepp MFaden AI. Inhibition of amyloid precursor protein secretases reduces recovery after spinal cord injury. Brain Res. 2014 Mar 11. pii: S0006-8993(14)00326-6. doi: 10.1016/j.brainres.2014.02.049. [Epub ahead of print]

Py, B.F., Desai, B.N., Jin, M., Penumaka, A., Zhu, H., Kober, M., Dietrich, A., Lipinski, M.M., Henry, T., Clapham, D.E. and Yuan, J. (2014) Caspase-11 controls interleukin-1β release through degradation of TRPC1. Cell Reports, accepted

Proctor, J.L., Fourney, W.L., Leiste, U.H., and Fiskum, G., Rat model of brain injury caused by under-vehicle blast-induced hyperacceleration. J. Trauma Acute Care Surgery (2014, in press)

Ryb GE, Dischsinger P, Auman KM, Kufera JA, Cooper C, Mackenzie C, and Kane RL.  S-100B doesn not predict outcome after mild traumatic brain injury.  Brain Injury (in press).

Stewart IJ, Fang R, Cannon JW, Zonies DH, Morrow BD, Orman JA, Oliver JD, Abbott KC, Jones JA, Chung KK. Derivation of candidates for the Combat Casualty Critical Care (C4) Database. Mil Med. 2014 Apr;179(4):370-4.

Sarkar, C., Zhao, Z., Aungst S, Sabirzhanov B, Faden AI, Lipinski MM.  Impaired autophagy flux is associated with neuronal cell death after TBI. Wu, J., Stoica, BA., Luo, T., Sabirzhanova,  B., Zhao, Z., Guanciale, K., Nayar, S,K,, Foss, C.A., Pomper, M.G., Faden, A.I. Isolated spinal cord contusion in rats induces chronic brain neuroinflammation, neurodegeneration and cognitive impairment: involvement of cell cycle activation.  (in press).

Srakar, C., Zhao, Z., Aungst, S., Sabirzhanov, B., Faden, A.I. and Lipinski, M.M.* (2014) Impaired autophagy due to lysosomal dysfunction may contribute to neuronal cell death after TBI. - in revision (Autophagy)

Stoica BA, Loane DJ, Zhao Z, Kabadi SV, Hanscom M, Byrnes KR, Faden AI. PARP-1 inhibition attenuates neuronal loss, microglia activation and neurological deficits after traumatic brain injury. Journal of Neurotrauma. 2014 Apr 15;31(8):758-72. doi: 10.1089/neu.2013.3194. Epub 2014 Jan 29.

Sun, X., Rai, R., Deschamps, J.R., MacKerell, A.D., Faden, A.I, Xue, F.  Boc-protected 1-(3-oxocycloalkyl)ureas via a one-step Curtius rearrangement: mechanism and scope.  Tetrahedron Letters.  (in press).

Sun, X. C., Raia, R., MacKerell, A. D., Faden, A.I, Xue, F.  Facile one-step synthesis of 2,5-diketopiperazines. Tetrahedron Letters, (in press). 2014.

Shackelford S, Colton K, Hess JR, Anazodo A, Dubose JJ, Stansbury L, Galvagno SM, Mackenzie CF. Early identification of uncontrolled hemorrhage after trauma: current status and future direction. J Trauma Acute Care Surg 2014; Accepted for publication on 26 December 2013.

Verster JC, Alford C, Bervoets AC, de Klerk S, Grange JA, Hogewoning A, Jones K, Kruisselbrink DL, Owen L, Piasecki TM, Raasveld SJ, Royle S, Slutske WS, Smith GS, Stephens R, Hangover Research Group TA. Hangover Research Needs: Proceedings of the 5th Alcohol Hangover Research Group Meeting. Curr Drug Abuse Rev. 2014 Jan 21;.

Zhu M, Cummings P, Zhao S, Coben JH, Smith GS. The association of graduated driver licensing with miles driven and fatal crash rates per miles driven among adolescents. Inj Prev. 2014 Feb 13;

Zarour A, El-Menyar A, Khattabi M, Tayyem R, Hamed O, Mahmood I, Abdelrahman H, Chiu W, Al-Thani H.  A Novel Practical Scoring for Early Diagnosis of Traumatic Bowel Injury Without Obvious Solid Organ Injury in Hemodynamically Stable Patients.  International Journal of Surgery.  January, 2014; 12 (4): 340-345.


Anderson D, Silberholz J, Golden M, Harrington M, Hirshon JM. An Empirical Analysis of the Effect of Residents on Emergency Department Treatment Times. IIE Transactions on Healthcare Systems Engineering 3(3):171-180 Jul 2013

Andrews PL, Scalea T, Habashi NM.  What’s in a name?  Mechanical ventilation is at the mercy of the operator.  Journal of Trauma.  74:1377, 2013.

Andrews P, Shiber J, Jaruga-Killeen E, Roy S, Sadowitz B, O'Toole R, Gatto L, Nieman G, Scalea T, Habashi N.  Early Application of Airway Pressure Release Ventilation May Reduce Mortality in High Risk Trauma Patients - A Systematic Review of Observational Trauma ARDS Literature. J Trauma 2013; In Press; manuscript # JT-D-12-01221R4.

Brenner M, Stein DM, Hu P, Kufera J, Wooford M, Scalea TM.  Early hyperoxia worsens outcomes after traumatic brain injury.  Archives Surgery.   2012 Jul 16:1-5. doi: 10.1001/archsurg.2012.1560. Epub ahead of print

Brown KM, Alcorta R, Weik TS, Lawner D, Ho S, Wright JL, Hirshon JM. The implementation and evaluation of an evidence-based statewide prehospital pain management protocol developed using the National Evidence-based Guideline Model Process for Emergency Medical Services. Prehosp Emerg Care 2014;18 Suppl 1:45-51.

Bradley M, Okoye O, Dubose J, Inaba K, Demetriades D, Scalea T, O'Connor J, Menaker J, Morales C, Shiflett T, Brown C. Risk factors for post-traumatic pneumonia in patients with retained haemothorax: Results of a prospective, observational AAST study. Injury. 2013 Feb 19. [Epub ahead of print]

Balan, I.S., Saladino, A.J., Aarabi, B., Castellani, R.J., Wade, C., Stein, D.M., Eisenberg, H.M., Chen, H.H., and Fiskum, G., Cellular alterations in human traumatic brain injury: changes in mitochondrial morphology reflect regional levels of injury severity. J Neurotrauma 30:367-381 (2013) (PMID: 23131111)

Boswell K, Menaker J. An update on spinal cord injury: Epidemiology, diagnosis and treatment for the emergency physician. Trauma Reports Jan/Feb 2013;14(1):1-12.

Clerc P, Young CA, Bordt EA, Grigore AM, Fiskum G, Polster BM. Magnesium sulfate protects against the bioenergetic consequences of chronic glutamate receptor stimulation. PLoS One 8:e79982. doi: 10.1371 (2013) (PMID: 24236167)

Colton K, Dinardo T, Hu PF, Xiong W, Hu EZ, Reed G, DuBose JJ, Stansbury LG, Mackenzie CF, Chiu WC, Miller C, Fang R, Stein DM, Scalea TM; ONPOINT Study Group. Full of sound and fury, signifying nothing: Burden of transient noncritical monitor alarms in a trauma resuscitation unit. J Trauma Nurs. 2013 Oct-Dec;20(4):184-8.

Calvello E, Reynolds T, Hirshon JM, Buckle C, Moresky R, O’Neill J, Wallis LA. Emergency care in sub-Saharan Africa: Results of a consensus conference.  African Journal of Emergency Medicine 2013 3, 42-48.  Available at:

Colton K, Dinardo T, Hu PF, Xiong W, Hu EZ, Reed G, DuBose JJ, Stansbury LG, Mackenzie CF, Chiu WC, Miller C, Fang R, Stein DM, Scalea TM; ONPOINT Study Group.  Full of Sound and Fury, Signifying Nothing:  Burden of Transient Noncritical Monitor Alarms in a Trauma Resuscitation Unit.  Journal of Trauma Nursing.  October-December, 2013; 20 (4): 184-188.

Dischinger PC, Ryb GE, Kufera JA, and Ho MS. Declining statewide trends in motor vehicle crashes and injury-related hospital admissions.  Ann Adv Automot Med. 2013; 57: 247-257.

Dale Y, Dutton R, Hu P, Chang Y, Brown C, Chen H, Grissom T, Kufera J, Scalea T.  Effect of Video Laryngoscopy on Trauma Patient Survival: A Randomized Controlled Trial. J Trauma Acute Care Surg. 2013 Aug; 75(2):212-9  PMID: 23823612

Deshpande SP, Grigore AM. Robotic Surgery is the Preferred Technique for CABG Surgery.  Journal of Cardiothoracic and Vascular Anesthesia. 2013;27(4):602-605.

Diamantidis CJ, Fink W, Yang S, Zuckerman M, Ginsberg J, Hu P, Xiao Y, Fink J. Directed use of the Internet for health information by patients with chronic kidney disease (CKD): results from Safe Kidney Care.  J Med Internet Res. 2013 Nov 15;15(11)   PMID: 24240617

Fitzpatrick M, Alexander HR, Deshpande SP, McCormick B, Martz DG, Jr, Grigore, AM. Use of Partial Veno-Venous Cardiopulmonary Bypass in Percutaneous Hepatic Perfusion for Patients with Diffuse, Isolated Liver Metastases: A Case Series Journal of Cardiothoracic and Vascular Anesthesia. J Cardiothorac Vasc Anesth. (In press)

Galvagno SM. Comparative effectiveness of helicopter emergency medical services compared to ground emergency medical services. Critical Care 2013; 17: 169. 

Galvagno SM, Hong CM, Lissauer ME, Baker AK, Murthi SB, Herr DL, Stein DM.  Practical considerations for the dosing and adjustment of continuous renal replacement therapy in the intensive care unit.  J Crit Care 2013 Jul 24 [Epub ahead of print], DOI: pii.S0883-9441(13)00143-3.

Galvagno Jr SM, Thomas S, Stephens C, Haut E, Hirshon JM, Floccare D, Pronovost P.  Helicopter emergency medical services for adults with major trauma. Cochrane Database Syst Rev. 2013 Mar 28 [Epub ahead of print]

Hirshon JM, Risko N, Calvello EJ, Stewart de Ramirez S, Narayan M, Theodosis C, O'Neill J; Acute Care Research Collaborative at the University of Maryland Global Health Initiative. Health systems and services: the role of acute care. Bull World Health Organ. 2013 May 1;91(5):386-8. Epub 2013 Jan 31.

Harris DG, Drucker CB, Brenner ML, Narayan M, Sarkar R, Scalea TM and Crawford RS.  Patterns and management of blunt iliac arterial injuries.  Journal of Vascular Surgery.  57(5), May 2013.

Hirshon JM, Comer AC, Rosenberg JH, Johnson JK, Moore SL, MacKenzie TD, Hall KK, Furuno JP. Methodological Challenges Associated with Developing and Implementing Antibiograms in Nursing Homes in Advances in the Prevention and Control of Healthcare-Associated Infections (HAI) series by AHRQ (In press) 

Hirshon JM, Hansoti B, Hauswald M, Sethuraman K, Kerr N, Scordino D, Biros M. Ethics in Acute Care Research: A Global Perspective and Research Agenda. Acad Emerg Med 2013 Dec;20(12):1251-8. 

Hargarten S, Martin IBK, Hauswald M, Hirshon JM. Global Health and Emergency Care:  What do we need to know to address the burden of illness and injury? Acad Emerg Med 2013 Dec;20(12):1213-5

Hess JR. L:elkens C, Holcomb JB, Scalea TM.  Advances in military, filed, and austere transfusion medicine in the last decade.  Transfusion and Apheresis Science. 49:380-386, 2013.

Hu P, Galvagno SM, Sen A, Dutton RP, Handley C, Shckelford S, Pasley JD, Mackenzie CF. Identification of dynamic pre-hospital changes with continuous vital signs acquisition. Air Med J. 2014 Jan-Feb;33(1):27-33. PMID: 24373474

Holmes JF, Lillis K, Monroe D, Borgialli D, Kerrey BT, Mahajan P, Adelgais K, Ellison AM, Yen K, Atabaki S, Menaker J, Bonsu B, Quayle KS, Garcia M, Rogers A, Blumberg S, Lee L, Tunik M, Kooistra J, Kwok M, Cook LJ, Dean JM, Sokolove PE, Wisner DH, Ehrlich P, Cooper A, Dayan PS, Wootton-Gorges S, Kuppermann N; Pediatric Emergency Care Applied Research Network (PECARN). Identifying Children at Very Low Risk of Clinically Important Blunt Abdominal Injuries. Ann Emerg Med. 2013 Jan 29. [Epub ahead of print]

Huffines M, Johnson KL, Smitz Naranjo LL, Lissauer ME, Fishel MAM, Howes SM, Pannullo D, Ralls M, Smith R. Improving Family Satisfaction and Participation in Decision Making in a Surgical ICU: a Multidisciplinary Collaborative Quality Improvement Project. Critical Care Nurse, Accepted for publication January 30, 2013

Inaba K, Menaker J, Branco BC, Gooch J, Okoye OT, Herrold J, Scalea TM, DuBose J, Demetriades D.  A prospective multicenter comparison of levetiracetam versus phenytoin for early post-traumatic seizure prophylaxis. J Trauma Acute Care Surg. 2013;74:766-73.

Jain A, Menaker J. Ultrasound for Trauma. Trauma Reports. May/June 2013;14(3):1-13.

Kashani K, Al-Khafaji A, Ardiles T, Artigas A, Bagshaw SM, Bell M, Bihorac A, Birkhahn R, Cely CM, Chawla LS, Davison DL, Feldkamp T, Forni LG, Gong MN, Gunnerson KJ, Haase M, Hackett J, Honore PM, Hoste EAJ, Joannes-Boyau O, Joannidis M, Kim P, Koyner JL, Laskowitz DT, Lissauer ME, Marx G, McCullough PA, Mullaney S, Ostermann M, Rimmele T, Shapiro NI, Shaw AD, Shi J, Sprague AM, Vincent JL, Vinsonneau C, Wagner L, Walker MG, Wilkerson RG, Zacharowski K, Kellum JA. Discovery and Validation of Cell Cycle Arrest Biomarkers in Human Acute Kidney Injury. Critical Care 2013; 17:R25

Kumar A, Stoica BA, Sabirzhanov B, Burns MP, FADEN AI, Loane DJ.  Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states.  Neurobiol Aging. 2013 May;34(5):1397-411. doi: 10.1016/j.neurobiolaging.2012.11.013. Epub 2012 Dec 27.

Kristian T, Hu B. Guidelines for using mouse global cerebral ischemia models. Transl Stroke Res. 2013 Jun;4(3):343-50. doi: 10.1007/s12975-012-0236-z. Epub 2012 Dec 14. PMID: 24323301 [PubMed - in process] 

Kalakonda, .S, Nallar, S.C., Jaber, S., Keay, S.K., Rorke, E., Munivenkatappa, R., Lindner, D.J., Fiskum, G.M., Kalvakolanu, D.V., Monoallelic loss of tumor suppressor GRIM-19 promotes tumorigenesis in mice. Proc Natl Acad Sci U S A. 110:E4213-4222 (2013) (PMID: 4145455)

Kragh JF, San Antonio J, Simmons JW, Mace JE, Stinner DJ, White CE, Fang R, Aden JK, Hsu JR, Eastridge BJ, Jenkins DH, Ritchie JD, Hardin MO, Ritenour AE, Wade CE, Blackbourne LH. Compartment syndrome performance improvement project is associated with increased combat casualty survival. J Trauma Acute Care Surg. 2013 Jan;74(1):259-263.

Lakkaraju, S.; Xue, F.; Faden, A.; MacKerell, A.  Estimation of ligand efficacies of metabotropic glutamate receptors from conformational forces obtained from molecular dynamics simulations.  Journal of Chemical Information and Modeling.  2013 Jun 24;53(6):1337-49. doi: 10.1021/ci400160x. Epub 2013 May 21

Laird MD, Clerc P, Polster BM, Fiskum G. Augmentation of normal and glutamate-impaired neuronal respiratory capacity by exogenous alternative biofuels. Transl Stroke Res. 4:643-651(2013) (PMID: 24323418)

Lee HJ, Wu J, Chung J, Wrathall JR (2013). SOX2 expression is up-regulated in adult spinal cord after contusion injury in both glial progenitors and ependymal stem cells. Journal of Neuroscience Research, 91(2):196-210. PMID:23169458.

Luo T, Wu J *(co-first author),  Kabadi SV, Sabirzhanov B, Guanciale K, Hanscom M, Faden J, Cardiff K, Bengson CJ, Faden AI (2013). Propofol Limits Microglial Activation after Experimental Brain Trauma through Inhibition of Nicotinamide Adenine Dinucleotide Phosphate Oxidase. Anesthesiology, 119(6):1370- 88. PMID: 24121215.

McAninch J, Greene C, Sorkin JD, Lavoie MC, Smith GS. Higher psychological distress is associated with unintentional injuries in US adults. Inj Prev. 2013 Oct 30;

Mirvis SE, Chiu WC.  MDCT Diagnosis of Post-Traumatic Hepatic Arterio-portal Fistulas.  Emergency Radiology.  June, 2013; 20 (3) 225-233.

Markandaya M, DuBose J, Fang R, Scalea T, Eastridge B, Cancio L, Blackbourne L.  Combat-related traumatic brain injury:  A prospective study of demographics and risk for early mortality.  Military Medicine.  In Press, 2012.

Mok JM, Jackson KL, Fang, R, Freedman BA. Effect of vacuum spine board immobilization on incidence of pressure ulcers during evacuation of military casualties from theater. Spine J. 2013 Dec;13(12):1801-8.

MacDonald C, Johnson A, Cooper D, Malone T, Sorrell J, Shimony J, Parsons M, Snyder A, Raichle M, Fang R, Flaherty S, Russell M, Brody D. Cerebellar white matter abnormalities following primary blast injury in US military personnel. PLoS ONE. 2013 Feb;8(2):e55823(1-8).

Menaker J, Kufera, JA, Glaser J, Stein DM, Scalea TM. Admission ASIA Motor Score Predicting The Need For Tracheostomy After Cervical Spinal Cord Injury.  J Trauma Acute Care Surg (Accepted) 

Millin MG, Galvagno SM, Khandker SR, Malki A, Bulger EM.  Withholding and termination of resuscitation of adult cardiopulmonary arrest secondary to trauma - resource document to the joint NAEMSP, ACS-COT position statements. J Trauma Acute Care Surg 2013; 75(3): 459-467.

Nguyen CT, Saksobhavivat N, Shanmuganathan K, Steenburg SD, Moeslein FM, Inaba K, Menaker J, Branco BC, Gooch J, Okoye OT, Herrold J, Scalea TM, DuBose, J, Demetriades D.  A prospective multicenter comparison of levetiracetam versus phenytoin for early posttraumatic seizure prophylaxis.  Journal of Trauma.  74:766-773, 2013.

Owens K, Park JH, Schuh R, Kristian T.  Mitochondrial dysfunction and NAD(+) metabolism alterations in the pathophysiology of acute brain injury. Transl Stroke Res. 2013 Dec;4(6):618-34. doi: 10.1007/s12975-013-0278-x. Epub 2013 Aug 10. PMID: 24323416 [PubMed - in process]

Owens K, Park JH, Kristian T. Utilizing commercial microwave for rapid and effective immunostaining. J Neurosci Methods. 2013 Sep 30;219(1):20-6. doi: 10.1016/j.jneumeth.2013.07.002. Epub 2013 Jul 12. PMID: 23856210 [PubMed - indexed for MEDLINE]

O’Connor JV, Chi A, Joshi M, DuBose J, Scalea TM.  Post-traumatic empyema:  Aetiology, surgery and outcome in 125 consecutive patients.  Injury. 44:1153-1158, 2013.

Odonkor P, Grigore A. Ischemic heart disease  Med Clin N AM. 2013; 97(6).

Park H, Kent J,Joshi M, Zhu S, Bochicchio GV, Henry S, Scalea T.  Percutaneous versus open tracheostomy:  comparison of procedures and surgical site infections.  Surgical Infections.  14:21-23, 2013. 

Piao CS, Stoica BA, Wu J, Sabirzhanov B, Zhao Z, Cabatbat R, Loane DJ, Faden AI (2013). Late exercise reduces neuroinflammation and cognitive dysfunction after traumatic brain injury. Neurobiology of Disease, 54:252-263. PMID: 23313314. doi: 10.1016/j.nbd.2012.12.017

Polster, B.M. (2013) AIF, reactive oxygen species, and neurodegeneration:  a “complex” problem.  Neurochem Int 62: 695-702. (Part of a special issue entitled "Oxidative Stress and Neurodegeneration")

Reynolds JC, Abraham MK, Barrueto FF Jr, Lemkin DL, Hirshon JM. Propofol for Procedural Sedation and Analgesia Reduced Dedicated Emergency Nursing Time While Maintaining Safety in a Community Emergency Department. J Emerg Nurs. 2013 May 6. [Epub ahead of print]

Robertson, C.L., Saraswati, M., Scafidi, S., Fiskum, G., Casey, P., and McKenna, M.C., Glucose metabolism in an immature rat model of pediatric traumatic brain injury. J Neurotrauma 30:2066-2072 (2013) (PMID: 24032394)

Roman P, Battafarano, RJ, Grigore AM. Anesthesia for Tracheal Reconstruction and Transplantation. Current Opinion in Anesthesiology. 2013 Feb; 26(1):1-5.

Ryb GE, Dischinger PC, Kleinberger M, McGwin G, Griffin RL. Aortic injuries in newer vehicles. Accid Anal Prev. 2013;59C:253-259.

Ryb GE, Dischinger P, Cooper C, Kufera JA. Does helicopter transport improve outcomes independently of emergency medical system time?J Trauma Acute Care Surg. 2013;74(1):149-54; discussion 154-6.

Ryb GE, Dischinger PC, Ho S. Causation and outcomes of diaphragmatic injuries in vehicular crashes. J Trauma Acute Care Surg. 2013;74(3):835-838.

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Stein DM, Jessie EM, Crane S, Kufera JA, Timmons T, Rodriguez CJ, Menaker J, Scalea TM.  Hyperacute adrenal insufficiency after hemorrhagic shock exists and is associated with poor outcomes.  Journal of Trauma.  74:363-370, 2013.

Stansbury LG, Hess AS, Thompson K, Kramer B, Scalea TM, Hess JR.  The clinical significance of platelet counts in the first 24 hours after severe injury.  Transfusion.  53:783-789,2013.

Sheth KN, Stein DM, Aarabi B, Hu P, Kufera JA, Scalea TM, Hanley DF.  Intracranial pressure does and outcome in traumatic brain injury.  NeuroCritical Care.  18:26-32, 2013.

Salah Eldin W, Hirshon JM, Smith GS, Kamal AA, Abou-El-Fetouh A, El-Setouhy M. Health-related quality of life after serious occupational injury in Egyptian workers: a cross-sectional study. BMJ Open. 2012;2(6).

Scalea JR, Menaker J, Meeks AK, Kramer M, Bartlett ST, Coopert M, Scalea TM.  Trauma patients with prior organ transplants-outcomes are better than expected:  a retrospective analysis.  Journal of Trauma.  74:1498-1503, 2013. 

Sheth KN, Stein DM, Aarabi B, Hu P, Kufera JA, Scalea TM, Hanley DF. Intracranial Pressure Dose and Outcome in Traumatic Brain Injury. Neurocrit Care. 2013 Feb;18(1):26-32. PMID:23055087

Silberholz J, Anderson D, Golden B, Harrington, M, Hirshon JM. The Impact of the Residency Teaching Model on the Efficiency of the Emergency Department at an Academic Center. Socio-Economic Planning Sciences.  47(3):183-189. Sep 2013

Stein D, Brenner M,  Hu P, Yang S, Hall E, Stansbury L, Menaker J,  Scalea T,   Timing of Intracranial Hypertension following Severe Traumatic Brain Injury.  Neurocrit Care. 2013 Jun;18(3):332-40. doi: 10.1007/s12028-013-9832-3.PMID:23494545

Stein DM, Jessie EM, Crane S, Kufera JA, Timmons T, Rodriguez CJ, Menaker J, Scalea TM.  Hyperacute adrenal insufficiency (HAI) after hemorrhagic shock exists and is associated with poor outcomes.  J Trauma Acute Care Surg. 2013;74(2):363-70

Stauffer C, Josiah AF, Fortes M, Menaker J, Cole JW. Lemierre Syndrome Secondary to Community-Acquired Methicillin-Resistant Staphylococcus Aureus Infection Associated with Cavernous Sinus Thromboses. J Emerg Med. 2013;44:e177-e182

Taylor JA, Lacovara AV, Smith GS, Pandian R, Lehto M. Near-miss narratives from the fire service: a Bayesian analysis. Accid Anal Prev. 2014 Jan;62:119-29.

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Wu J, Renn CL, Faden AI, Dorsey SG. TrkB.T1 contributes to neuropathic pain following spinal cord injury through regulation of cell cycle pathways. Journal of Neuroscience, 24 July 2013, 33(30):12447-12463; doi:10.1523/JNEUROSCI.0846-13.2013

Wu J, Raver C, Piao C, Keller A, Faden AI.  Cell Cycle Activation Contributes to Increased Neuronal Activity in the Posterior Thalamic Nucleus and Associated Chronic Hyperesthesia after Rat Spinal Cord Contusion.  Neurotherapeutics. 2013 Jul;10(3):520-38. doi: 10.1007/s13311-013-0198-1.

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Xue, F.; Stoica, B. A.; Hanscom, M.; Kabadi, S. V.; FADEN A.I.  Positive Allosteric Modulators (PAMs) of Metabotropic Glutamate Receptor 5 (mGluR5) Attenuate Microglial Activation. CNS & Neurol. Disord. Drug Targets 2013, in press.

Yeatts DJ, Dutton RP, Hu PF, Chang Y, Brown CH, Chen H, Grissom TE, Kufera JA, Scalea TM.  Effect of video laryngoscopy on trauma patient survival:  A randomized controlled trial.  J Trauma Acute Care Surg.  75:212-219, 2013.

Zhao, Z., Faden, A., Loane, D., Lipinski, M., Sabirzhanov, B. and Stoica, B. (2013) Neuroprotective effects of geranylgeranylacetone in experimental traumatic brain injury. J Cereb Blood Flow Metab, 33:1897-908

Zhu M, Zhao S, Coben JH, Smith GS. Why more male pedestrians die in vehicle-pedestrian collisions than female pedestrians: a decompositional analysis. Inj Prev. 2013 Aug;19(4):227-31.

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Zarour AM, El-Menyar A, Al-Thani H, Scalea TM, Chiu WC.  Presentations and Outcomes in Patients with Traumatic Diaphragmatic Injury:  A 15-Year Experience.  The Journal of Trauma and Acute Care Surgery.  June, 2013; 74 (6): 1392-1398.